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Journal Abstract Search


640 related items for PubMed ID: 22065587

  • 1. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB.
    J Biol Chem; 2012 Jan 02; 287(1):245-256. PubMed ID: 22065587
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  • 2. Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.
    Harikumar KB, Kunnumakkara AB, Ahn KS, Anand P, Krishnan S, Guha S, Aggarwal BB.
    Blood; 2009 Feb 26; 113(9):2003-13. PubMed ID: 18952893
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  • 3. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B, Pandey MK, Aggarwal BB.
    Mol Pharmacol; 2007 Jun 26; 71(6):1703-14. PubMed ID: 17387141
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  • 4. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB.
    Cancer Res; 2008 Jul 01; 68(13):5370-9. PubMed ID: 18593939
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  • 5. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun 01; 7(6):1604-14. PubMed ID: 18566231
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  • 6. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
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  • 8. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G, Ahn KS, Aggarwal BB.
    Mol Cancer Res; 2008 Jun 29; 6(6):1059-70. PubMed ID: 18567808
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  • 9. Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis.
    Jin HR, Jin SZ, Cai XF, Li D, Wu X, Nan JX, Lee JJ, Jin X.
    PLoS One; 2012 Jun 29; 7(6):e40355. PubMed ID: 22768286
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  • 10. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1.
    Shishodia S, Majumdar S, Banerjee S, Aggarwal BB.
    Cancer Res; 2003 Aug 01; 63(15):4375-83. PubMed ID: 12907607
    [Abstract] [Full Text] [Related]

  • 11. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB.
    Clin Cancer Res; 2006 Mar 15; 12(6):1828-38. PubMed ID: 16551868
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  • 13. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB.
    Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421
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  • 15. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S, Gupta S.
    Clin Cancer Res; 2004 May 01; 10(9):3169-78. PubMed ID: 15131058
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  • 19. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
    Takada Y, Khuri FR, Aggarwal BB.
    J Biol Chem; 2004 Jun 18; 279(25):26287-99. PubMed ID: 15090542
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  • 20. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB, Ichikawa H, Anand P, Mohankumar CJ, Hema PS, Nair MS, Aggarwal BB.
    Mol Cancer Ther; 2008 Oct 18; 7(10):3306-17. PubMed ID: 18852134
    [Abstract] [Full Text] [Related]


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