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261 related items for PubMed ID: 22075556

  • 1. AKT inhibition by triciribine alone or as combination therapy for growth control of gastroenteropancreatic neuroendocrine tumors.
    Gloesenkamp CR, Nitzsche B, Ocker M, Di Fazio P, Quint K, Hoffmann B, Scherübl H, Höpfner M.
    Int J Oncol; 2012 Mar; 40(3):876-88. PubMed ID: 22075556
    [Abstract] [Full Text] [Related]

  • 2. Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors.
    Gloesenkamp C, Nitzsche B, Lim AR, Normant E, Vosburgh E, Schrader M, Ocker M, Scherübl H, Höpfner M.
    Int J Oncol; 2012 May; 40(5):1659-67. PubMed ID: 22246317
    [Abstract] [Full Text] [Related]

  • 3. mTOR Pathway in Gastroenteropancreatic Neuroendocrine Tumor (GEP-NETs).
    Zanini S, Renzi S, Giovinazzo F, Bermano G.
    Front Endocrinol (Lausanne); 2020 May; 11():562505. PubMed ID: 33304317
    [Abstract] [Full Text] [Related]

  • 4. IFN-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro.
    Vitale G, de Herder WW, van Koetsveld PM, Waaijers M, Schoordijk W, Croze E, Colao A, Lamberts SW, Hofland LJ.
    Cancer Res; 2006 Jan 01; 66(1):554-62. PubMed ID: 16397272
    [Abstract] [Full Text] [Related]

  • 5. JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer.
    Qiu H, Li J, Clark LH, Jackson AL, Zhang L, Guo H, Kilgore JE, Gehrig PA, Zhou C, Bae-Jump VL.
    Oncotarget; 2016 Oct 11; 7(41):66809-66821. PubMed ID: 27572308
    [Abstract] [Full Text] [Related]

  • 6. 1,25-dihydroxyvitamin D(3) and PI3K/AKT inhibitors synergistically inhibit growth and induce senescence in prostate cancer cells.
    Axanova LS, Chen YQ, McCoy T, Sui G, Cramer SD.
    Prostate; 2010 Nov 01; 70(15):1658-71. PubMed ID: 20583132
    [Abstract] [Full Text] [Related]

  • 7. Amiloride sensitizes human pancreatic cancer cells to erlotinib in vitro through inhibition of the PI3K/AKT signaling pathway.
    Zheng YT, Yang HY, Li T, Zhao B, Shao TF, Xiang XQ, Cai WM.
    Acta Pharmacol Sin; 2015 May 01; 36(5):614-26. PubMed ID: 25864651
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of phosphatidylinositol 3-kinase/Akt signaling suppresses tumor cell proliferation and neuroendocrine marker expression in GI carcinoid tumors.
    Pitt SC, Chen H, Kunnimalaiyaan M.
    Ann Surg Oncol; 2009 Oct 01; 16(10):2936-42. PubMed ID: 19588205
    [Abstract] [Full Text] [Related]

  • 9. Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.
    Fraedrich K, Schrader J, Ittrich H, Keller G, Gontarewicz A, Matzat V, Kromminga A, Pace A, Moll J, Bläker M, Lohse AW, Hörsch D, Brümmendorf TH, Benten D.
    Clin Cancer Res; 2012 Sep 01; 18(17):4621-32. PubMed ID: 22753592
    [Abstract] [Full Text] [Related]

  • 10. A novel approach in the treatment of neuroendocrine gastrointestinal tumors: additive antiproliferative effects of interferon-gamma and meta-iodobenzylguanidine.
    Höpfner M, Sutter AP, Huether A, Ahnert-Hilger G, Scherübl H.
    BMC Cancer; 2004 May 21; 4():23. PubMed ID: 15154969
    [Abstract] [Full Text] [Related]

  • 11. Advances in the systemic treatment of neuroendocrine tumors in the era of molecular therapy.
    Leung R, Lang B, Wong H, Chiu J, Yat WK, Shek T, Cho WY, Yau LC, Yau T.
    Anticancer Agents Med Chem; 2013 Mar 21; 13(3):382-8. PubMed ID: 23092266
    [Abstract] [Full Text] [Related]

  • 12. Molecular markers associated with response to chemotherapy in gastro-entero-pancreatic neuroendocrine tumors.
    O'Toole D, Couvelard A, Rebours V, Zappa M, Hentic O, Hammel P, Levy P, Bedossa P, Raymond E, Ruszniewski P.
    Endocr Relat Cancer; 2010 Dec 21; 17(4):847-56. PubMed ID: 20570957
    [Abstract] [Full Text] [Related]

  • 13. Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.
    Mueller A, Bachmann E, Linnig M, Khillimberger K, Schimanski CC, Galle PR, Moehler M.
    Cancer Chemother Pharmacol; 2012 Jun 21; 69(6):1601-15. PubMed ID: 22543857
    [Abstract] [Full Text] [Related]

  • 14. IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells.
    Ma J, Sawai H, Matsuo Y, Ochi N, Yasuda A, Takahashi H, Wakasugi T, Funahashi H, Sato M, Takeyama H.
    J Surg Res; 2010 May 01; 160(1):90-101. PubMed ID: 19560785
    [Abstract] [Full Text] [Related]

  • 15. Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN-regulated PI3K/Akt signaling pathway.
    Jing X, Cheng W, Wang S, Li P, He L.
    Oncol Rep; 2016 Jan 01; 35(1):472-8. PubMed ID: 26530632
    [Abstract] [Full Text] [Related]

  • 16. Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway.
    Huang KF, Zhang GD, Huang YQ, Diao Y.
    Int Immunopharmacol; 2012 Feb 01; 12(2):334-41. PubMed ID: 22182776
    [Abstract] [Full Text] [Related]

  • 17. Perifosine-mediated Akt inhibition in neuroendocrine tumor cells: role of specific Akt isoforms.
    Zitzmann K, Vlotides G, Brand S, Lahm H, Spöttl G, Göke B, Auernhammer CJ.
    Endocr Relat Cancer; 2012 Jun 01; 19(3):423-34. PubMed ID: 22499437
    [Abstract] [Full Text] [Related]

  • 18. PTEN Inhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERT Pathway in Lung Adenocarcinoma A549 Cells.
    Lu XX, Cao LY, Chen X, Xiao J, Zou Y, Chen Q.
    Biomed Res Int; 2016 Jun 01; 2016():2476842. PubMed ID: 27822469
    [Abstract] [Full Text] [Related]

  • 19. PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells.
    Ma J, Sawai H, Ochi N, Matsuo Y, Xu D, Yasuda A, Takahashi H, Wakasugi T, Takeyama H.
    Mol Cell Biochem; 2009 Nov 01; 331(1-2):161-71. PubMed ID: 19437103
    [Abstract] [Full Text] [Related]

  • 20. Triciribine Phosphate Monohydrate, an AKT Inhibitor, Enhances Gemcitabine Activity in Pancreatic Cancer Cells.
    Kim R, Yamauchi T, Husain K, Sebti S, Malafa M.
    Anticancer Res; 2015 Sep 01; 35(9):4599-604. PubMed ID: 26254348
    [Abstract] [Full Text] [Related]


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