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Journal Abstract Search

371 related items for PubMed ID: 22075993

  • 1. Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.
    Wollenick K, Hu J, Kristiansen G, Schraml P, Rehrauer H, Berchner-Pfannschmidt U, Fandrey J, Wenger RH, Stiehl DP.
    Nucleic Acids Res; 2012 Mar; 40(5):1928-43. PubMed ID: 22075993
    [Abstract] [Full Text] [Related]

  • 2. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.
    Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.
    PLoS One; 2010 Jun 21; 5(6):e11241. PubMed ID: 20574527
    [Abstract] [Full Text] [Related]

  • 3. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia.
    Fujita N, Markova D, Anderson DG, Chiba K, Toyama Y, Shapiro IM, Risbud MV.
    J Biol Chem; 2012 May 11; 287(20):16975-86. PubMed ID: 22451659
    [Abstract] [Full Text] [Related]

  • 4. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
    Lim CS, Kiriakidis S, Paleolog EM, Davies AH.
    J Vasc Surg; 2012 May 11; 55(5):1427-39. PubMed ID: 22277691
    [Abstract] [Full Text] [Related]

  • 5. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E.
    Biochem J; 2004 Aug 01; 381(Pt 3):761-7. PubMed ID: 15104534
    [Abstract] [Full Text] [Related]

  • 6. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O, Chandramouli GV, Wood M, Vasselli JR, Riss J, Maranchie JK, Linehan WM, Barrett JC.
    J Cell Biochem; 2004 Jun 01; 92(3):491-501. PubMed ID: 15156561
    [Abstract] [Full Text] [Related]

  • 7. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
    Chintala S, Najrana T, Toth K, Cao S, Durrani FA, Pili R, Rustum YM.
    BMC Cancer; 2012 Jul 17; 12():293. PubMed ID: 22804960
    [Abstract] [Full Text] [Related]

  • 8. Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors.
    Henze AT, Riedel J, Diem T, Wenner J, Flamme I, Pouyseggur J, Plate KH, Acker T.
    Cancer Res; 2010 Jan 01; 70(1):357-66. PubMed ID: 20028863
    [Abstract] [Full Text] [Related]

  • 9. Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
    Pientka FK, Hu J, Schindler SG, Brix B, Thiel A, Jöhren O, Fandrey J, Berchner-Pfannschmidt U, Depping R.
    J Cell Sci; 2012 Nov 01; 125(Pt 21):5168-76. PubMed ID: 22946054
    [Abstract] [Full Text] [Related]

  • 10. Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia.
    Kunze R, Zhou W, Veltkamp R, Wielockx B, Breier G, Marti HH.
    Stroke; 2012 Oct 01; 43(10):2748-56. PubMed ID: 22933585
    [Abstract] [Full Text] [Related]

  • 11. The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
    Barth S, Nesper J, Hasgall PA, Wirthner R, Nytko KJ, Edlich F, Katschinski DM, Stiehl DP, Wenger RH, Camenisch G.
    Mol Cell Biol; 2007 May 01; 27(10):3758-68. PubMed ID: 17353276
    [Abstract] [Full Text] [Related]

  • 12. Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.
    Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L.
    J Biol Chem; 2010 Jan 22; 285(4):2601-9. PubMed ID: 19880525
    [Abstract] [Full Text] [Related]

  • 13. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
    Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM.
    J Biol Chem; 2004 Sep 10; 279(37):38458-65. PubMed ID: 15247232
    [Abstract] [Full Text] [Related]

  • 14. Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
    Schoepflin ZR, Shapiro IM, Risbud MV.
    J Bone Miner Res; 2016 Jun 10; 31(6):1287-99. PubMed ID: 26765925
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1.
    Rajendran G, Schonfeld MP, Tiwari R, Huang S, Torosyan R, Fields T, Park J, Susztak K, Kapitsinou PP.
    J Am Soc Nephrol; 2020 Mar 10; 31(3):501-516. PubMed ID: 31996410
    [Abstract] [Full Text] [Related]

  • 16. Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.
    Aprelikova O, Wood M, Tackett S, Chandramouli GV, Barrett JC.
    Cancer Res; 2006 Jun 01; 66(11):5641-7. PubMed ID: 16740701
    [Abstract] [Full Text] [Related]

  • 17. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
    Li J, Yuan W, Jiang S, Ye W, Yang H, Shapiro IM, Risbud MV.
    J Biol Chem; 2015 Mar 13; 290(11):7195-207. PubMed ID: 25635047
    [Abstract] [Full Text] [Related]

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  • 19. Hypoxia-inducible factor prolyl-hydroxylase 2 senses high-salt intake to increase hypoxia inducible factor 1alpha levels in the renal medulla.
    Wang Z, Zhu Q, Xia M, Li PL, Hinton SJ, Li N.
    Hypertension; 2010 May 13; 55(5):1129-36. PubMed ID: 20308610
    [Abstract] [Full Text] [Related]

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