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1618 related items for PubMed ID: 22080879

  • 21. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May; 31(5):673-82. PubMed ID: 17007924
    [Abstract] [Full Text] [Related]

  • 22. Inhibition of phosphatidylinositol-3-kinase causes cell death through a protein kinase B (PKB)-dependent mechanism and growth arrest through a PKB-independent mechanism.
    Gottschalk AR, Doan A, Nakamura JL, Haas-Kogan DA, Stokoe D.
    Int J Radiat Oncol Biol Phys; 2005 Mar 15; 61(4):1183-8. PubMed ID: 15752900
    [Abstract] [Full Text] [Related]

  • 23. LY294002 induces G0/G1 cell cycle arrest and apoptosis of cancer stem-like cells from human osteosarcoma via down-regulation of PI3K activity.
    Gong C, Liao H, Wang J, Lin Y, Qi J, Qin L, Tian LQ, Guo FJ.
    Asian Pac J Cancer Prev; 2012 Mar 15; 13(7):3103-7. PubMed ID: 22994717
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  • 24. Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002.
    Kunnimalaiyaan M, Ndiaye M, Chen H.
    Surgery; 2006 Dec 15; 140(6):1009-14; discussion 1014-5. PubMed ID: 17188151
    [Abstract] [Full Text] [Related]

  • 25. Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.
    Xie X, Tang B, Zhou J, Gao Q, Zhang P.
    Oncol Rep; 2013 Aug 15; 30(2):773-82. PubMed ID: 23743572
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  • 26. Inhibition of Prostate Cancer DU-145 Cells Proliferation by Anthopleura anjunae Oligopeptide (YVPGP) via PI3K/AKT/mTOR Signaling Pathway.
    Li X, Tang Y, Yu F, Sun Y, Huang F, Chen Y, Yang Z, Ding G.
    Mar Drugs; 2018 Sep 11; 16(9):. PubMed ID: 30208576
    [Abstract] [Full Text] [Related]

  • 27. Zedoarondiol Inhibits Platelet-Derived Growth Factor-Induced Vascular Smooth Muscle Cells Proliferation via Regulating AMP-Activated Protein Kinase Signaling Pathway.
    Mao H, Tao T, Song D, Liu M, Wang X, Liu X, Shi D.
    Cell Physiol Biochem; 2016 Sep 11; 40(6):1506-1520. PubMed ID: 27997894
    [Abstract] [Full Text] [Related]

  • 28. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Sep 11; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 29. Synergistic Antitumor Effect of BKM120 with Prima-1Met Via Inhibiting PI3K/AKT/mTOR and CPSF4/hTERT Signaling and Reactivating Mutant P53.
    Li Z, Xu X, Li Y, Zou K, Zhang Z, Xu X, Liao Y, Zhao X, Jiang W, Yu W, Guo W, Chen Y, Li Y, Chen M, Deng WG, Li L, Zou L.
    Cell Physiol Biochem; 2018 Sep 11; 45(5):1772-1786. PubMed ID: 29495002
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  • 30. Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer.
    Furuya F, Lu C, Willingham MC, Cheng SY.
    Carcinogenesis; 2007 Dec 11; 28(12):2451-8. PubMed ID: 17660507
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  • 31. [Cyr61 expression influences cancer cell proliferation and apoptosis via PI3K pathway in human ovarian carcinoma cells].
    Xiao L, He C, Li X, Chen Y, Zhou JD.
    Zhonghua Fu Chan Ke Za Zhi; 2012 Aug 11; 47(8):616-20. PubMed ID: 23141184
    [Abstract] [Full Text] [Related]

  • 32. Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor.
    Du L, Smolewski P, Bedner E, Traganos F, Darzynkiewicz Z.
    Int J Oncol; 2001 Oct 11; 19(4):811-9. PubMed ID: 11562760
    [Abstract] [Full Text] [Related]

  • 33. Metformin exerts an antitumor effect by inhibiting bladder cancer cell migration and growth, and promoting apoptosis through the PI3K/AKT/mTOR pathway.
    Shen Z, Xue D, Wang K, Zhang F, Shi J, Jia B, Yang D, Zhang Q, Zhang S, Jiang H, Luo D, Li X, Zhong Q, Zhang J, Peng Z, Han Y, Sima C, He X, Hao L.
    BMC Urol; 2022 May 24; 22(1):79. PubMed ID: 35610639
    [Abstract] [Full Text] [Related]

  • 34. The O-methylated isoflavone, formononetin, inhibits human ovarian cancer cell proliferation by sub G0/G1 cell phase arrest through PI3K/AKT and ERK1/2 inactivation.
    Park S, Bazer FW, Lim W, Song G.
    J Cell Biochem; 2018 Sep 24; 119(9):7377-7387. PubMed ID: 29761845
    [Abstract] [Full Text] [Related]

  • 35. Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway.
    Yang ZP, Zhao Y, Huang F, Chen J, Yao YH, Li J, Wu XN.
    World J Gastroenterol; 2015 Sep 28; 21(36):10385-99. PubMed ID: 26420965
    [Abstract] [Full Text] [Related]

  • 36. Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity.
    Gaelzer MM, Coelho BP, de Quadros AH, Hoppe JB, Terra SR, Guerra MC, Usach V, Guma FC, Gonçalves CA, Setton-Avruj P, Battastini AM, Salbego CG.
    PLoS One; 2016 Sep 28; 11(4):e0154612. PubMed ID: 27123999
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  • 37. LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells.
    Liu JJ, Duan RD.
    Anticancer Res; 2009 Aug 28; 29(8):2987-91. PubMed ID: 19661305
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  • 38. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT.
    Int J Oncol; 2010 Oct 28; 37(4):1023-30. PubMed ID: 20811725
    [Abstract] [Full Text] [Related]

  • 39. Probing the PI3K/Akt/mTor pathway using 31P-NMR spectroscopy: routes to glycogen synthase kinase 3.
    Phyu SM, Tseng CC, Fleming IN, Smith TA.
    Sci Rep; 2016 Nov 04; 6():36544. PubMed ID: 27811956
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  • 40. Activation of phosphatidylinositol-3'-kinase/AKT signaling is essential in hepatoblastoma survival.
    Hartmann W, Küchler J, Koch A, Friedrichs N, Waha A, Endl E, Czerwitzki J, Metzger D, Steiner S, Wurst P, Leuschner I, von Schweinitz D, Buettner R, Pietsch T.
    Clin Cancer Res; 2009 Jul 15; 15(14):4538-45. PubMed ID: 19584164
    [Abstract] [Full Text] [Related]

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