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Journal Abstract Search

138 related items for PubMed ID: 2208122

  • 1. Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker.
    Greenfield RS, Kaneko T, Daues A, Edson MA, Fitzgerald KA, Olech LJ, Grattan JA, Spitalny GL, Braslawsky GR.
    Cancer Res; 1990 Oct 15; 50(20):6600-7. PubMed ID: 2208122
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  • 2. Antitumor activity of adriamycin (hydrazone-linked) immunoconjugates compared with free adriamycin and specificity of tumor cell killing.
    Braslawsky GR, Edson MA, Pearce W, Kaneko T, Greenfield RS.
    Cancer Res; 1990 Oct 15; 50(20):6608-14. PubMed ID: 2208123
    [Abstract] [Full Text] [Related]

  • 3. Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.
    King HD, Yurgaitis D, Willner D, Firestone RA, Yang MB, Lasch SJ, Hellström KE, Trail PA.
    Bioconjug Chem; 1999 Oct 15; 10(2):279-88. PubMed ID: 10077478
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  • 4. Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates.
    Trail PA, Willner D, Knipe J, Henderson AJ, Lasch SJ, Zoeckler ME, TrailSmith MD, Doyle TW, King HD, Casazza AM, Braslawsky GR, Brown J, Hofstead SJ, Greenfield RS, Firestone RA, Mosure K, Kadow KF, Yang MB, Hellström KE, Hellström I.
    Cancer Res; 1997 Jan 01; 57(1):100-5. PubMed ID: 8988048
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  • 5. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate.
    Sanderson RJ, Hering MA, James SF, Sun MM, Doronina SO, Siadak AW, Senter PD, Wahl AF.
    Clin Cancer Res; 2005 Jan 15; 11(2 Pt 1):843-52. PubMed ID: 15701875
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  • 6. Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity.
    Braslawsky GR, Kadow K, Knipe J, McGoff K, Edson M, Kaneko T, Greenfield RS.
    Cancer Immunol Immunother; 1991 Jan 15; 33(6):367-74. PubMed ID: 1878890
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  • 12. In vitro and in vivo antitumor activity of immunoconjugates prepared by linking 5-fluorouridine to antiadenocarcinoma monoclonal antibody.
    Brusa P, Dosio F, Coppo S, Pacchioni D, Arpicco S, Crosasso P, Cattel L.
    Farmaco; 1997 Feb 15; 52(2):71-81. PubMed ID: 9181686
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  • 13. New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.
    Thorpe PE, Wallace PM, Knowles PP, Relf MG, Brown AN, Watson GJ, Knyba RE, Wawrzynczak EJ, Blakey DC.
    Cancer Res; 1987 Nov 15; 47(22):5924-31. PubMed ID: 3499221
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  • 14. Development of potent monoclonal antibody auristatin conjugates for cancer therapy.
    Doronina SO, Toki BE, Torgov MY, Mendelsohn BA, Cerveny CG, Chace DF, DeBlanc RL, Gearing RP, Bovee TD, Siegall CB, Francisco JA, Wahl AF, Meyer DL, Senter PD.
    Nat Biotechnol; 2003 Jul 15; 21(7):778-84. PubMed ID: 12778055
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  • 15. New hydrazone derivatives of adriamycin and their immunoconjugates--a correlation between acid stability and cytotoxicity.
    Kaneko T, Willner D, Monkovíc I, Knipe JO, Braslawsky GR, Greenfield RS, Vyas DM.
    Bioconjug Chem; 1991 Jul 15; 2(3):133-41. PubMed ID: 1932212
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