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115 related items for PubMed ID: 22086658

  • 1. Pemetrexed induces both intrinsic and extrinsic apoptosis through ataxia telangiectasia mutated/p53-dependent and -independent signaling pathways.
    Yang TY, Chang GC, Chen KC, Hung HW, Hsu KH, Wu CH, Sheu GT, Hsu SL.
    Mol Carcinog; 2013 Mar; 52(3):183-94. PubMed ID: 22086658
    [Abstract] [Full Text] [Related]

  • 2. ATM/ATR and SMAD3 pathways contribute to 3-indole-induced G₁ arrest in cancer cells and xenograft models.
    Huang SM, Lu KT, Wang YC.
    Anticancer Res; 2011 Jan; 31(1):203-8. PubMed ID: 21273599
    [Abstract] [Full Text] [Related]

  • 3. Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells.
    Yang TY, Chang GC, Chen KC, Hung HW, Hsu KH, Sheu GT, Hsu SL.
    Eur J Pharmacol; 2011 Aug 01; 663(1-3):17-26. PubMed ID: 21575631
    [Abstract] [Full Text] [Related]

  • 4. Gallic acid induces apoptosis of lung fibroblasts via a reactive oxygen species-dependent ataxia telangiectasia mutated-p53 activation pathway.
    Chuang CY, Liu HC, Wu LC, Chen CY, Chang JT, Hsu SL.
    J Agric Food Chem; 2010 Mar 10; 58(5):2943-51. PubMed ID: 20151649
    [Abstract] [Full Text] [Related]

  • 5. Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells.
    Lai JM, Chang JT, Wen CL, Hsu SL.
    Eur J Pharmacol; 2009 Nov 25; 623(1-3):1-9. PubMed ID: 19744477
    [Abstract] [Full Text] [Related]

  • 6. Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells.
    Su L, Liu G, Hao X, Zhong N, Zhong D, Liu X, Singhal S.
    Eur J Cancer; 2011 Nov 25; 47(16):2471-8. PubMed ID: 21726997
    [Abstract] [Full Text] [Related]

  • 7. Chromium-mediated apoptosis: involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes.
    Hill R, Leidal AM, Madureira PA, Gillis LD, Waisman DM, Chiu A, Lee PW.
    DNA Repair (Amst); 2008 Sep 01; 7(9):1484-99. PubMed ID: 18602874
    [Abstract] [Full Text] [Related]

  • 8. miR-181a and miR-630 regulate cisplatin-induced cancer cell death.
    Galluzzi L, Morselli E, Vitale I, Kepp O, Senovilla L, Criollo A, Servant N, Paccard C, Hupé P, Robert T, Ripoche H, Lazar V, Harel-Bellan A, Dessen P, Barillot E, Kroemer G.
    Cancer Res; 2010 Mar 01; 70(5):1793-803. PubMed ID: 20145152
    [Abstract] [Full Text] [Related]

  • 9. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner.
    Amantini C, Ballarini P, Caprodossi S, Nabissi M, Morelli MB, Lucciarini R, Cardarelli MA, Mammana G, Santoni G.
    Carcinogenesis; 2009 Aug 01; 30(8):1320-9. PubMed ID: 19502594
    [Abstract] [Full Text] [Related]

  • 10. Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.
    Chiu YJ, Hour MJ, Lu CC, Chung JG, Kuo SC, Huang WW, Chen HJ, Jin YA, Yang JS.
    J Orthop Res; 2011 Sep 01; 29(9):1448-56. PubMed ID: 21425328
    [Abstract] [Full Text] [Related]

  • 11. Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells.
    Yim H, Hwang IS, Choi JS, Chun KH, Jin YH, Ham YM, Lee KY, Lee SK.
    J Cell Biol; 2006 Jul 03; 174(1):77-88. PubMed ID: 16801388
    [Abstract] [Full Text] [Related]

  • 12. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling.
    Biton S, Ashkenazi A.
    Cell; 2011 Apr 01; 145(1):92-103. PubMed ID: 21458669
    [Abstract] [Full Text] [Related]

  • 13. Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53.
    Wang J, Pabla N, Wang CY, Wang W, Schoenlein PV, Dong Z.
    Am J Physiol Renal Physiol; 2006 Dec 01; 291(6):F1300-7. PubMed ID: 16849690
    [Abstract] [Full Text] [Related]

  • 14. Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM.
    Luciani MG, Campregher C, Gasche C.
    Carcinogenesis; 2007 Oct 01; 28(10):2207-17. PubMed ID: 17510082
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of beta-carotene-induced apoptosis of gastric cancer cells: involvement of ataxia-telangiectasia-mutated.
    Jang SH, Lim JW, Kim H.
    Ann N Y Acad Sci; 2009 Aug 01; 1171():156-62. PubMed ID: 19723050
    [Abstract] [Full Text] [Related]

  • 16. Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated Modulator of Apoptosis.
    Li W, Du B, Wang T, Wang S, Zhang J.
    Chem Biol Interact; 2009 Jan 27; 177(2):121-7. PubMed ID: 19028473
    [Abstract] [Full Text] [Related]

  • 17. Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells.
    Buqué A, Muhialdin JSh, Muñoz A, Calvo B, Carrera S, Aresti U, Sancho A, Rubio I, López-Vivanco G.
    Mol Cancer; 2012 Apr 26; 11():25. PubMed ID: 22537194
    [Abstract] [Full Text] [Related]

  • 18. Expression profiling-based subtyping identifies novel non-small cell lung cancer subgroups and implicates putative resistance to pemetrexed therapy.
    Hou J, Lambers M, den Hamer B, den Bakker MA, Hoogsteden HC, Grosveld F, Hegmans J, Aerts J, Philipsen S.
    J Thorac Oncol; 2012 Jan 26; 7(1):105-14. PubMed ID: 22134068
    [Abstract] [Full Text] [Related]

  • 19. Defects in apoptotic signal transduction in cisplatin-resistant non-small cell lung cancer cells.
    Ikuta K, Takemura K, Kihara M, Naito S, Lee E, Shimizu E, Yamauchi A.
    Oncol Rep; 2005 Jun 26; 13(6):1229-34. PubMed ID: 15870947
    [Abstract] [Full Text] [Related]

  • 20. The role of Pemetrexed (Alimta , LY231514) in lung cancer therapy.
    Molina JR, Adjei AA.
    Clin Lung Cancer; 2003 Jul 26; 5(1):21-7. PubMed ID: 14596699
    [Abstract] [Full Text] [Related]

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