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232 related items for PubMed ID: 22090143

  • 1. Binding of anti-membrane-proximal gp41 monoclonal antibodies to CD4-liganded and -unliganded human immunodeficiency virus type 1 and simian immunodeficiency virus virions.
    Rathinakumar R, Dutta M, Zhu P, Johnson WE, Roux KH.
    J Virol; 2012 Feb; 86(3):1820-31. PubMed ID: 22090143
    [Abstract] [Full Text] [Related]

  • 2. The broadly neutralizing anti-human immunodeficiency virus type 1 4E10 monoclonal antibody is better adapted to membrane-bound epitope recognition and blocking than 2F5.
    Huarte N, Lorizate M, Maeso R, Kunert R, Arranz R, Valpuesta JM, Nieva JL.
    J Virol; 2008 Sep; 82(18):8986-96. PubMed ID: 18596094
    [Abstract] [Full Text] [Related]

  • 3. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10.
    Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, Wang M, Hessell A, Wilson IA, Binley JM, Dawson PE, Burton DR, Zwick MB.
    J Virol; 2007 Apr; 81(8):4033-43. PubMed ID: 17287272
    [Abstract] [Full Text] [Related]

  • 4. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L.
    Hessell AJ, Rakasz EG, Tehrani DM, Huber M, Weisgrau KL, Landucci G, Forthal DN, Koff WC, Poignard P, Watkins DI, Burton DR.
    J Virol; 2010 Feb; 84(3):1302-13. PubMed ID: 19906907
    [Abstract] [Full Text] [Related]

  • 5. Stable docking of neutralizing human immunodeficiency virus type 1 gp41 membrane-proximal external region monoclonal antibodies 2F5 and 4E10 is dependent on the membrane immersion depth of their epitope regions.
    Dennison SM, Stewart SM, Stempel KC, Liao HX, Haynes BF, Alam SM.
    J Virol; 2009 Oct; 83(19):10211-23. PubMed ID: 19640992
    [Abstract] [Full Text] [Related]

  • 6. The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.
    Alam SM, McAdams M, Boren D, Rak M, Scearce RM, Gao F, Camacho ZT, Gewirth D, Kelsoe G, Chen P, Haynes BF.
    J Immunol; 2007 Apr 01; 178(7):4424-35. PubMed ID: 17372000
    [Abstract] [Full Text] [Related]

  • 7. Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.
    Lai RP, Yan J, Heeney J, McClure MO, Göttlinger H, Luban J, Pizzato M.
    PLoS Pathog; 2011 Dec 01; 7(12):e1002442. PubMed ID: 22194689
    [Abstract] [Full Text] [Related]

  • 8. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma.
    Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE.
    J Virol; 2006 Mar 01; 80(6):3030-41. PubMed ID: 16501112
    [Abstract] [Full Text] [Related]

  • 9. In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1.
    Leaman DP, Kinkead H, Zwick MB.
    J Virol; 2010 Apr 01; 84(7):3382-95. PubMed ID: 20089658
    [Abstract] [Full Text] [Related]

  • 10. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.
    Zwick MB, Jensen R, Church S, Wang M, Stiegler G, Kunert R, Katinger H, Burton DR.
    J Virol; 2005 Jan 01; 79(2):1252-61. PubMed ID: 15613352
    [Abstract] [Full Text] [Related]

  • 11. Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane.
    Montero M, Gulzar N, Klaric KA, Donald JE, Lepik C, Wu S, Tsai S, Julien JP, Hessell AJ, Wang S, Lu S, Burton DR, Pai EF, Degrado WF, Scott JK.
    J Virol; 2012 Mar 01; 86(6):2930-41. PubMed ID: 22238313
    [Abstract] [Full Text] [Related]

  • 12. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.
    Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, Moore JP, Stiegler G, Katinger H, Burton DR, Parren PW.
    J Virol; 2001 Nov 01; 75(22):10892-905. PubMed ID: 11602729
    [Abstract] [Full Text] [Related]

  • 13. Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid epitopes.
    Matyas GR, Wieczorek L, Beck Z, Ochsenbauer-Jambor C, Kappes JC, Michael NL, Polonis VR, Alving CR.
    AIDS; 2009 Oct 23; 23(16):2069-77. PubMed ID: 19710597
    [Abstract] [Full Text] [Related]

  • 14. Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution.
    Shen X, Dennison SM, Liu P, Gao F, Jaeger F, Montefiori DC, Verkoczy L, Haynes BF, Alam SM, Tomaras GD.
    Proc Natl Acad Sci U S A; 2010 Mar 30; 107(13):5972-7. PubMed ID: 20231447
    [Abstract] [Full Text] [Related]

  • 15. Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.
    Zhang MY, Vu BK, Choudhary A, Lu H, Humbert M, Ong H, Alam M, Ruprecht RM, Quinnan G, Jiang S, Montefiori DC, Mascola JR, Broder CC, Haynes BF, Dimitrov DS.
    J Virol; 2008 Jul 30; 82(14):6869-79. PubMed ID: 18480433
    [Abstract] [Full Text] [Related]

  • 16. In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth.
    Shen X, Parks RJ, Montefiori DC, Kirchherr JL, Keele BF, Decker JM, Blattner WA, Gao F, Weinhold KJ, Hicks CB, Greenberg ML, Hahn BH, Shaw GM, Haynes BF, Tomaras GD.
    J Virol; 2009 Apr 30; 83(8):3617-25. PubMed ID: 19193787
    [Abstract] [Full Text] [Related]

  • 17. Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles.
    Phogat S, Svehla K, Tang M, Spadaccini A, Muller J, Mascola J, Berkower I, Wyatt R.
    Virology; 2008 Mar 30; 373(1):72-84. PubMed ID: 18155743
    [Abstract] [Full Text] [Related]

  • 18. Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10.
    Klein JS, Gnanapragasam PN, Galimidi RP, Foglesong CP, West AP, Bjorkman PJ.
    Proc Natl Acad Sci U S A; 2009 May 05; 106(18):7385-90. PubMed ID: 19372381
    [Abstract] [Full Text] [Related]

  • 19. Anti-HIV-1 antibodies 2F5 and 4E10 interact differently with lipids to bind their epitopes.
    Franquelim HG, Chiantia S, Veiga AS, Santos NC, Schwille P, Castanho MA.
    AIDS; 2011 Feb 20; 25(4):419-28. PubMed ID: 21245727
    [Abstract] [Full Text] [Related]

  • 20. Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.
    Alam SM, Scearce RM, Parks RJ, Plonk K, Plonk SG, Sutherland LL, Gorny MK, Zolla-Pazner S, Vanleeuwen S, Moody MA, Xia SM, Montefiori DC, Tomaras GD, Weinhold KJ, Karim SA, Hicks CB, Liao HX, Robinson J, Shaw GM, Haynes BF.
    J Virol; 2008 Jan 20; 82(1):115-25. PubMed ID: 17942537
    [Abstract] [Full Text] [Related]

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