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192 related items for PubMed ID: 22094461

  • 1. Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of action.
    Di Fulvio M, Frondorf K, Henkels KM, Grunwald WC, Cool D, Gomez-Cambronero J.
    J Biol Chem; 2012 Jan 02; 287(1):393-407. PubMed ID: 22094461
    [Abstract] [Full Text] [Related]

  • 2. Mammalian target of rapamycin (mTOR) and S6 kinase down-regulate phospholipase D2 basal expression and function.
    Tabatabaian F, Dougherty K, Di Fulvio M, Gomez-Cambronero J.
    J Biol Chem; 2010 Jun 18; 285(25):18991-9001. PubMed ID: 20410302
    [Abstract] [Full Text] [Related]

  • 3. Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR.
    Lehman N, Ledford B, Di Fulvio M, Frondorf K, McPhail LC, Gomez-Cambronero J.
    FASEB J; 2007 Apr 18; 21(4):1075-87. PubMed ID: 17242159
    [Abstract] [Full Text] [Related]

  • 4. A new signaling pathway (JAK-Fes-phospholipase D) that is enhanced in highly proliferative breast cancer cells.
    Ye Q, Kantonen S, Henkels KM, Gomez-Cambronero J.
    J Biol Chem; 2013 Apr 05; 288(14):9881-9891. PubMed ID: 23404507
    [Abstract] [Full Text] [Related]

  • 5. New concepts in phospholipase D signaling in inflammation and cancer.
    Gomez-Cambronero J.
    ScientificWorldJournal; 2010 Jul 07; 10():1356-69. PubMed ID: 20623096
    [Abstract] [Full Text] [Related]

  • 6. Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling.
    Frondorf K, Henkels KM, Frohman MA, Gomez-Cambronero J.
    J Biol Chem; 2010 May 21; 285(21):15837-47. PubMed ID: 20304930
    [Abstract] [Full Text] [Related]

  • 7. The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).
    Gomez-Cambronero J.
    Cell Signal; 2011 Dec 21; 23(12):1885-95. PubMed ID: 21740967
    [Abstract] [Full Text] [Related]

  • 8. The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts.
    Knapek K, Frondorf K, Post J, Short S, Cox D, Gomez-Cambronero J.
    Mol Cell Biol; 2010 Sep 21; 30(18):4492-506. PubMed ID: 20647543
    [Abstract] [Full Text] [Related]

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  • 13. PLD2 forms a functional complex with mTOR/raptor to transduce mitogenic signals.
    Ha SH, Kim DH, Kim IS, Kim JH, Lee MN, Lee HJ, Kim JH, Jang SK, Suh PG, Ryu SH.
    Cell Signal; 2006 Dec 21; 18(12):2283-91. PubMed ID: 16837165
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  • 15. Sustained PKCβII activity confers oncogenic properties in a phospholipase D- and mTOR-dependent manner.
    El Osta M, Liu M, Adada M, Senkal CE, Idkowiak-Baldys J, Obeid LM, Clarke CJ, Hannun YA.
    FASEB J; 2014 Jan 21; 28(1):495-505. PubMed ID: 24121461
    [Abstract] [Full Text] [Related]

  • 16. Expression and regulation of phospholipase D isoforms in mammalian cell lines.
    Gibbs TC, Meier KE.
    J Cell Physiol; 2000 Jan 21; 182(1):77-87. PubMed ID: 10567919
    [Abstract] [Full Text] [Related]

  • 17. Src homology 2 domain substitution modulates the kinase and transforming activities of the Fes protein-tyrosine kinase.
    Rogers JA, Cheng HY, Smithgall TE.
    Cell Growth Differ; 2000 Nov 21; 11(11):581-92. PubMed ID: 11095247
    [Abstract] [Full Text] [Related]

  • 18. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
    Toschi A, Lee E, Xu L, Garcia A, Gadir N, Foster DA.
    Mol Cell Biol; 2009 Mar 21; 29(6):1411-20. PubMed ID: 19114562
    [Abstract] [Full Text] [Related]

  • 19. Elevated expression of the c-fes proto-oncogene in adult human myeloid leukemia cells in the absence of gene amplification.
    Smithgall TE, Johnston JB, Bustin M, Glazer RI.
    J Natl Cancer Inst; 1991 Jan 02; 83(1):42-6. PubMed ID: 1984516
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  • 20. Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells.
    Kharbanda S, Saleem A, Emoto Y, Stone R, Rapp U, Kufe D.
    J Biol Chem; 1994 Jan 14; 269(2):872-8. PubMed ID: 8288641
    [Abstract] [Full Text] [Related]

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