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239 related items for PubMed ID: 22105074

  • 1. Evolutionarily conserved residues at glucagon-like peptide-1 (GLP-1) receptor core confer ligand-induced receptor activation.
    Moon MJ, Kim HY, Park S, Kim DK, Cho EB, Park CR, You DJ, Hwang JI, Kim K, Choe H, Seong JY.
    J Biol Chem; 2012 Feb 03; 287(6):3873-84. PubMed ID: 22105074
    [Abstract] [Full Text] [Related]

  • 2. Ligand binding pocket formed by evolutionarily conserved residues in the glucagon-like peptide-1 (GLP-1) receptor core domain.
    Moon MJ, Lee YN, Park S, Reyes-Alcaraz A, Hwang JI, Millar RP, Choe H, Seong JY.
    J Biol Chem; 2015 Feb 27; 290(9):5696-706. PubMed ID: 25561730
    [Abstract] [Full Text] [Related]

  • 3. Tyr1 and Ile7 of glucose-dependent insulinotropic polypeptide (GIP) confer differential ligand selectivity toward GIP and glucagon-like peptide-1 receptors.
    Moon MJ, Kim HY, Kim SG, Park J, Choi DS, Hwang JI, Seong JY.
    Mol Cells; 2010 Aug 27; 30(2):149-54. PubMed ID: 20799012
    [Abstract] [Full Text] [Related]

  • 4. Localization of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor.
    Gelling RW, Wheeler MB, Xue J, Gyomorey S, Nian C, Pederson RA, McIntosh CH.
    Endocrinology; 1997 Jun 27; 138(6):2640-3. PubMed ID: 9165060
    [Abstract] [Full Text] [Related]

  • 5. Structural basis for ligand recognition of incretin receptors.
    Underwood CR, Parthier C, Reedtz-Runge S.
    Vitam Horm; 2010 Jun 27; 84():251-78. PubMed ID: 21094903
    [Abstract] [Full Text] [Related]

  • 6. Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
    Coopman K, Wallis R, Robb G, Brown AJ, Wilkinson GF, Timms D, Willars GB.
    Mol Endocrinol; 2011 Oct 27; 25(10):1804-18. PubMed ID: 21868452
    [Abstract] [Full Text] [Related]

  • 7. Insights into the structure and activation mechanism of some class B1 GPCR family members.
    Aksu H, Demirbilek A, Uba AI.
    Mol Biol Rep; 2024 Sep 06; 51(1):966. PubMed ID: 39240462
    [Abstract] [Full Text] [Related]

  • 8. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation.
    Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM.
    J Biol Chem; 2012 Feb 03; 287(6):3642-58. PubMed ID: 22147710
    [Abstract] [Full Text] [Related]

  • 9. Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
    Jones B, McGlone ER, Fang Z, Pickford P, Corrêa IR, Oishi A, Jockers R, Inoue A, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Tomas A, Bloom SR.
    J Biol Chem; 2021 Feb 03; 296():100133. PubMed ID: 33268378
    [Abstract] [Full Text] [Related]

  • 10. Umami receptor activation increases duodenal bicarbonate secretion via glucagon-like peptide-2 release in rats.
    Wang JH, Inoue T, Higashiyama M, Guth PH, Engel E, Kaunitz JD, Akiba Y.
    J Pharmacol Exp Ther; 2011 Nov 03; 339(2):464-73. PubMed ID: 21846840
    [Abstract] [Full Text] [Related]

  • 11. The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively.
    Al-Sabah S, Al-Fulaij M, Shaaban G, Ahmed HA, Mann RJ, Donnelly D, Bünemann M, Krasel C.
    PLoS One; 2014 Nov 03; 9(9):e106890. PubMed ID: 25191754
    [Abstract] [Full Text] [Related]

  • 12. A comparative transcriptomic analysis of glucagon-like peptide-1 receptor- and glucose-dependent insulinotropic polypeptide receptor-expressing cells in the hypothalamus.
    Smith C, Patterson-Cross R, Woodward O, Lewis J, Chiarugi D, Merkle F, Gribble F, Reimann F, Adriaenssens A.
    Appetite; 2022 Jul 01; 174():106022. PubMed ID: 35430298
    [Abstract] [Full Text] [Related]

  • 13. Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors.
    Brubaker PL, Drucker DJ.
    Recept Channels; 2002 Jul 01; 8(3-4):179-88. PubMed ID: 12529935
    [Abstract] [Full Text] [Related]

  • 14. Expression of glucagon-like peptide-1 receptor and glucose‑dependent insulinotropic polypeptide receptor is regulated by the glucose concentration in mouse osteoblastic MC3T3-E1 cells.
    Aoyama E, Watari I, Podyma-Inoue KA, Yanagishita M, Ono T.
    Int J Mol Med; 2014 Aug 01; 34(2):475-82. PubMed ID: 24866833
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of the insulinotropic and glucose-lowering actions of zebrafish GIP in mammalian systems: Evidence for involvement of the GLP-1 receptor.
    Graham GV, Conlon JM, Abdel-Wahab YH, Gault VA, Flatt PR.
    Peptides; 2018 Feb 01; 100():182-189. PubMed ID: 29157578
    [Abstract] [Full Text] [Related]

  • 16. Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor.
    Underwood CR, Garibay P, Knudsen LB, Hastrup S, Peters GH, Rudolph R, Reedtz-Runge S.
    J Biol Chem; 2010 Jan 01; 285(1):723-30. PubMed ID: 19861722
    [Abstract] [Full Text] [Related]

  • 17. Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity.
    Runge S, Wulff BS, Madsen K, Bräuner-Osborne H, Knudsen LB.
    Br J Pharmacol; 2003 Mar 01; 138(5):787-94. PubMed ID: 12642379
    [Abstract] [Full Text] [Related]

  • 18. Glucagon-like peptides-1 from phylogenetically ancient fish show potent anti-diabetic activities by acting as dual GLP1R and GCGR agonists.
    Graham GV, Conlon JM, Abdel-Wahab YH, Flatt PR.
    Mol Cell Endocrinol; 2019 Jan 15; 480():54-64. PubMed ID: 30312651
    [Abstract] [Full Text] [Related]

  • 19. GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice.
    Hansotia T, Drucker DJ.
    Regul Pept; 2005 Jun 15; 128(2):125-34. PubMed ID: 15780432
    [Abstract] [Full Text] [Related]

  • 20. Characterization of glucagon-like peptide-1 receptor-binding determinants.
    Xiao Q, Jeng W, Wheeler MB.
    J Mol Endocrinol; 2000 Dec 15; 25(3):321-35. PubMed ID: 11116211
    [Abstract] [Full Text] [Related]

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