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Journal Abstract Search

204 related items for PubMed ID: 22113921

  • 1.
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  • 2. Inhibition of cathepsin K increases modeling-based bone formation, and improves cortical dimension and strength in adult ovariectomized monkeys.
    Pennypacker BL, Chen CM, Zheng H, Shih MS, Belfast M, Samadfam R, Duong LT.
    J Bone Miner Res; 2014 Aug; 29(8):1847-58. PubMed ID: 24591096
    [Abstract] [Full Text] [Related]

  • 3. Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys.
    Masarachia PJ, Pennypacker BL, Pickarski M, Scott KR, Wesolowski GA, Smith SY, Samadfam R, Goetzmann JE, Scott BB, Kimmel DB, Duong LT.
    J Bone Miner Res; 2012 Mar; 27(3):509-23. PubMed ID: 22113859
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  • 4. Effects of long term treatment with high doses of odanacatib on bone mass, bone strength, and remodeling/modeling in newly ovariectomized monkeys.
    Duong LT, Pickarski M, Cusick T, Chen CM, Zhuo Y, Scott K, Samadfam R, Smith SY, Pennypacker BL.
    Bone; 2016 Jul; 88():113-124. PubMed ID: 27126999
    [Abstract] [Full Text] [Related]

  • 5. Odanacatib, effects of 16-month treatment and discontinuation of therapy on bone mass, turnover and strength in the ovariectomized rabbit model of osteopenia.
    Duong LT, Crawford R, Scott K, Winkelmann CT, Wu G, Szczerba P, Gentile MA.
    Bone; 2016 Dec; 93():86-96. PubMed ID: 27639811
    [Abstract] [Full Text] [Related]

  • 6. Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: a head-to-head comparison with alendronate.
    Williams DS, McCracken PJ, Purcell M, Pickarski M, Mathers PD, Savitz AT, Szumiloski J, Jayakar RY, Somayajula S, Krause S, Brown K, Winkelmann CT, Scott BB, Cook L, Motzel SL, Hargreaves R, Evelhoch JL, Cabal A, Dardzinski BJ, Hangartner TN, Duong LT.
    Bone; 2013 Oct; 56(2):489-96. PubMed ID: 23806798
    [Abstract] [Full Text] [Related]

  • 7. Effects of Odanacatib on bone mineralization density distribution in thoracic spine and femora of ovariectomized adult rhesus monkeys: a quantitative backscattered electron imaging study.
    Fratzl-Zelman N, Roschger P, Fisher JE, Duong LT, Klaushofer K.
    Calcif Tissue Int; 2013 Mar; 92(3):261-9. PubMed ID: 23179105
    [Abstract] [Full Text] [Related]

  • 8. Effects of 16-month treatment with the cathepsin K inhibitor ONO-5334 on bone markers, mineral density, strength and histomorphometry in ovariectomized cynomolgus monkeys.
    Yamada H, Ochi Y, Mori H, Nishikawa S, Hashimoto Y, Nakanishi Y, Tanaka M, Bruce M, Deacon S, Kawabata K.
    Bone; 2016 May; 86():43-52. PubMed ID: 26921823
    [Abstract] [Full Text] [Related]

  • 9. Potential role of odanacatib in the treatment of osteoporosis.
    Ng KW.
    Clin Interv Aging; 2012 May; 7():235-47. PubMed ID: 22866001
    [Abstract] [Full Text] [Related]

  • 10. Differing Effects of Parathyroid Hormone, Alendronate, and Odanacatib on Bone Formation and on the Mineralization Process in Intracortical and Endocortical Bone of Ovariectomized Rabbits.
    Vrahnas C, Buenzli PR, Pearson TA, Pennypacker BL, Tobin MJ, Bambery KR, Duong LT, Sims NA.
    Calcif Tissue Int; 2018 Dec; 103(6):625-637. PubMed ID: 30019315
    [Abstract] [Full Text] [Related]

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  • 13. Effects of odanacatib on the radius and tibia of postmenopausal women: improvements in bone geometry, microarchitecture, and estimated bone strength.
    Cheung AM, Majumdar S, Brixen K, Chapurlat R, Fuerst T, Engelke K, Dardzinski B, Cabal A, Verbruggen N, Ather S, Rosenberg E, de Papp AE.
    J Bone Miner Res; 2014 Aug; 29(8):1786-94. PubMed ID: 24643905
    [Abstract] [Full Text] [Related]

  • 14. Effects of Long-Term Odanacatib Treatment on Bone Gene Expression in Ovariectomized Adult Rhesus Monkeys: Differentiation From Alendronate.
    Muise ES, Podtelezhnikov AA, Pickarski M, Loboda A, Tan Y, Hu G, Thomspon JR, Duong le T.
    J Bone Miner Res; 2016 Apr; 31(4):839-51. PubMed ID: 26587671
    [Abstract] [Full Text] [Related]

  • 15. Effects of treatment of ovariectomized adult rhesus monkeys with parathyroid hormone 1-84 for 16 months on trabecular and cortical bone structure and biomechanical properties of the proximal femur.
    Fox J, Miller MA, Recker RR, Turner CH, Smith SY.
    Calcif Tissue Int; 2007 Jul; 81(1):53-63. PubMed ID: 17551766
    [Abstract] [Full Text] [Related]

  • 16. Effects of daily treatment with parathyroid hormone 1-84 for 16 months on density, architecture and biomechanical properties of cortical bone in adult ovariectomized rhesus monkeys.
    Fox J, Miller MA, Newman MK, Recker RR, Turner CH, Smith SY.
    Bone; 2007 Sep; 41(3):321-30. PubMed ID: 17573250
    [Abstract] [Full Text] [Related]

  • 17. Treatment of skeletally mature ovariectomized rhesus monkeys with PTH(1-84) for 16 months increases bone formation and density and improves trabecular architecture and biomechanical properties at the lumbar spine.
    Fox J, Miller MA, Newman MK, Turner CH, Recker RR, Smith SY.
    J Bone Miner Res; 2007 Feb; 22(2):260-73. PubMed ID: 17087625
    [Abstract] [Full Text] [Related]

  • 18. Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys.
    Jerome C, Missbach M, Gamse R.
    Osteoporos Int; 2012 Jan; 23(1):339-49. PubMed ID: 21380636
    [Abstract] [Full Text] [Related]

  • 19. Progressive increases in bone mass and bone strength in an ovariectomized rat model of osteoporosis after 26 weeks of treatment with a sclerostin antibody.
    Li X, Niu QT, Warmington KS, Asuncion FJ, Dwyer D, Grisanti M, Han CY, Stolina M, Eschenberg MJ, Kostenuik PJ, Simonet WS, Ominsky MS, Ke HZ.
    Endocrinology; 2014 Dec; 155(12):4785-97. PubMed ID: 25259718
    [Abstract] [Full Text] [Related]

  • 20. Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys.
    Jerome C, Missbach M, Gamse R.
    Osteoporos Int; 2011 Dec; 22(12):3001-11. PubMed ID: 21308366
    [Abstract] [Full Text] [Related]

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