These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

420 related items for PubMed ID: 22126990

  • 21. PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.
    Holmstock N, Gonzalez FJ, Baes M, Annaert P, Augustijns P.
    Mol Pharm; 2013 Mar 04; 10(3):1056-62. PubMed ID: 23360470
    [Abstract] [Full Text] [Related]

  • 22. Cytochrome P450 3A4 mRNA is a more reliable marker than CYP3A4 activity for detecting pregnane X receptor-activated induction of drug-metabolizing enzymes.
    Fahmi OA, Kish M, Boldt S, Obach RS.
    Drug Metab Dispos; 2010 Sep 04; 38(9):1605-11. PubMed ID: 20566695
    [Abstract] [Full Text] [Related]

  • 23. Hepatic early inflammation induces downregulation of hepatic cytochrome P450 expression and metabolic activity in the dextran sulfate sodium-induced murine colitis.
    Kusunoki Y, Ikarashi N, Hayakawa Y, Ishii M, Kon R, Ochiai W, Machida Y, Sugiyama K.
    Eur J Pharm Sci; 2014 Apr 11; 54():17-27. PubMed ID: 24413062
    [Abstract] [Full Text] [Related]

  • 24. Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia.
    Niemira M, Dastych J, Mazerska Z.
    Biochem Pharmacol; 2013 Jul 15; 86(2):231-41. PubMed ID: 23688499
    [Abstract] [Full Text] [Related]

  • 25.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 26.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 27. Drug-drug interactions and metabolism in cytochrome P450 2C knockout mice: application to troleandomycin and midazolam.
    Grimsley A, Gallagher R, Hutchison M, Pickup K, Wilson ID, Samuelsson K.
    Biochem Pharmacol; 2013 Aug 15; 86(4):529-38. PubMed ID: 23732297
    [Abstract] [Full Text] [Related]

  • 28. CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
    Inoue T, Nitta K, Sugihara K, Horie T, Kitamura S, Ohta S.
    Drug Metab Dispos; 2008 Dec 15; 36(12):2429-33. PubMed ID: 18784266
    [Abstract] [Full Text] [Related]

  • 29.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 30. SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells.
    Tan H, Xu C, Zeng H, Wang Y, Li Y, Fan X, Chen P, Jiang Y, Chen X, Huang M, Bi H.
    J Pharmacol Sci; 2016 Feb 15; 130(2):66-71. PubMed ID: 26782648
    [Abstract] [Full Text] [Related]

  • 31. Rifampin-Mediated Induction of Tamoxifen Metabolism in a Humanized PXR-CAR-CYP3A4/3A7-CYP2D6 Mouse Model.
    Chang JH, Chen J, Liu L, Messick K, Ly J.
    Drug Metab Dispos; 2016 Nov 15; 44(11):1736-1741. PubMed ID: 27538915
    [Abstract] [Full Text] [Related]

  • 32. Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
    Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Ohshita H, Tateno C, Horie T, Kitamura S, Ohta S.
    Drug Metab Dispos; 2012 Feb 15; 40(2):322-8. PubMed ID: 22048522
    [Abstract] [Full Text] [Related]

  • 33.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 34. CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver.
    Iwahori T, Matsuura T, Maehashi H, Sugo K, Saito M, Hosokawa M, Chiba K, Masaki T, Aizaki H, Ohkawa K, Suzuki T.
    Hepatology; 2003 Mar 15; 37(3):665-73. PubMed ID: 12601364
    [Abstract] [Full Text] [Related]

  • 35. The role of human CYP2C8 and CYP2C9 variants in pioglitazone metabolism in vitro.
    Muschler E, Lal J, Jetter A, Rattay A, Zanger U, Zadoyan G, Fuhr U, Kirchheiner J.
    Basic Clin Pharmacol Toxicol; 2009 Dec 15; 105(6):374-9. PubMed ID: 19614891
    [Abstract] [Full Text] [Related]

  • 36.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 37. Utility of CYP3A4 and PXR-CAR-CYP3A4/3A7 Transgenic Mouse Models To Assess the Magnitude of CYP3A4 Mediated Drug-Drug Interactions.
    Ly JQ, Messick K, Qin A, Takahashi RH, Choo EF.
    Mol Pharm; 2017 May 01; 14(5):1754-1759. PubMed ID: 28345929
    [Abstract] [Full Text] [Related]

  • 38.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 39.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 40.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

    Page: [Previous] [Next] [New Search]
    of 21.