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140 related items for PubMed ID: 22127878

  • 1. Probing the intestinal α-glucosidase enzyme specificities of starch-digesting maltase-glucoamylase and sucrase-isomaltase: synthesis and inhibitory properties of 3'- and 5'-maltose-extended de-O-sulfonated ponkoranol.
    Eskandari R, Jones K, Reddy KR, Jayakanthan K, Chaudet M, Rose DR, Pinto BM.
    Chemistry; 2011 Dec 23; 17(52):14817-25. PubMed ID: 22127878
    [Abstract] [Full Text] [Related]

  • 2. Naturally occurring sulfonium-ion glucosidase inhibitors and their derivatives: a promising class of potential antidiabetic agents.
    Mohan S, Eskandari R, Pinto BM.
    Acc Chem Res; 2014 Jan 21; 47(1):211-25. PubMed ID: 23964564
    [Abstract] [Full Text] [Related]

  • 3. The effect of heteroatom substitution of sulfur for selenium in glucosidase inhibitors on intestinal α-glucosidase activities.
    Eskandari R, Jones K, Rose DR, Pinto BM.
    Chem Commun (Camb); 2011 Aug 28; 47(32):9134-6. PubMed ID: 21750824
    [Abstract] [Full Text] [Related]

  • 4. Probing the active-site requirements of human intestinal N-terminal maltase glucoamylase: the effect of replacing the sulfate moiety by a methyl ether in ponkoranol, a naturally occurring α-glucosidase inhibitor.
    Eskandari R, Jones K, Rose DR, Pinto BM.
    Bioorg Med Chem Lett; 2010 Oct 01; 20(19):5686-9. PubMed ID: 20801033
    [Abstract] [Full Text] [Related]

  • 5. Studies directed toward the stereochemical structure determination of the naturally occurring glucosidase inhibitor, kotalanol: synthesis and inhibitory activities against human maltase glucoamylase of seven-carbon, chain-extended homologues of salacinol.
    Nasi R, Patrick BO, Sim L, Rose DR, Pinto BM.
    J Org Chem; 2008 Aug 15; 73(16):6172-81. PubMed ID: 18651773
    [Abstract] [Full Text] [Related]

  • 6. Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase.
    Jones K, Sim L, Mohan S, Kumarasamy J, Liu H, Avery S, Naim HY, Quezada-Calvillo R, Nichols BL, Pinto BM, Rose DR.
    Bioorg Med Chem; 2011 Jul 01; 19(13):3929-34. PubMed ID: 21669536
    [Abstract] [Full Text] [Related]

  • 7. Selectivity of 3'-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelae.
    Eskandari R, Jones K, Rose DR, Pinto BM.
    Bioorg Med Chem Lett; 2011 Nov 01; 21(21):6491-4. PubMed ID: 21924903
    [Abstract] [Full Text] [Related]

  • 8. Potent glucosidase inhibitors: de-O-sulfonated ponkoranol and its stereoisomer.
    Eskandari R, Kuntz DA, Rose DR, Pinto BM.
    Org Lett; 2010 Apr 02; 12(7):1632-5. PubMed ID: 20218632
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of S-alkylated sulfonium-ions and their glucosidase inhibitory activities against recombinant human maltase glucoamylase.
    Mohan S, Sim L, Rose DR, Pinto BM.
    Carbohydr Res; 2007 May 21; 342(7):901-12. PubMed ID: 17316580
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of analogues of salacinol containing a carboxylate inner salt and their inhibitory activities against human maltase glucoamylase.
    Chen W, Sim L, Rose DR, Pinto BM.
    Carbohydr Res; 2007 Sep 03; 342(12-13):1661-7. PubMed ID: 17597595
    [Abstract] [Full Text] [Related]

  • 11. New chain-extended analogues of salacinol and blintol and their glycosidase inhibitory activities. Mapping the active-site requirements of human maltase glucoamylase.
    Nasi R, Sim L, Rose DR, Pinto BM.
    J Org Chem; 2007 Jan 05; 72(1):180-6. PubMed ID: 17194097
    [Abstract] [Full Text] [Related]

  • 12. Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.
    Mohan S, Sim L, Rose DR, Pinto BM.
    Bioorg Med Chem; 2010 Nov 15; 18(22):7794-8. PubMed ID: 20970346
    [Abstract] [Full Text] [Related]

  • 13. New synthetic routes to chain-extended selenium, sulfur, and nitrogen analogues of the naturally occurring glucosidase inhibitor salacinol and their inhibitory activities against recombinant human maltase glucoamylase.
    Liu H, Nasi R, Jayakanthan K, Sim L, Heipel H, Rose DR, Pinto BM.
    J Org Chem; 2007 Aug 17; 72(17):6562-72. PubMed ID: 17658854
    [Abstract] [Full Text] [Related]

  • 14. The membrane-bound intestinal enzymes of waxwings and thrushes: adaptive and functional implications of patterns of enzyme activity.
    Witmer MC, Martínez del Rio C.
    Physiol Biochem Zool; 2001 Aug 17; 74(4):584-93. PubMed ID: 11436143
    [Abstract] [Full Text] [Related]

  • 15. Investigations of the structures and inhibitory properties of intestinal maltase glucoamylase and sucrase isomaltase.
    Jones K, Eskandari R, Naim HY, Pinto BM, Rose DR.
    J Pediatr Gastroenterol Nutr; 2012 Nov 17; 55 Suppl 2():S20-4. PubMed ID: 23103645
    [No Abstract] [Full Text] [Related]

  • 16. Mammalian maltase-glucoamylase and sucrase-isomaltase inhibitory effects of Artocarpus heterophyllus: An in vitro and in silico approach.
    Abdulhaniff P, Sakayanathan P, Loganathan C, Iruthayaraj A, Thiyagarajan R, Thayumanavan P.
    Comput Biol Chem; 2024 Jun 17; 110():108052. PubMed ID: 38492557
    [Abstract] [Full Text] [Related]

  • 17. New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
    Sim L, Jayakanthan K, Mohan S, Nasi R, Johnston BD, Pinto BM, Rose DR.
    Biochemistry; 2010 Jan 26; 49(3):443-51. PubMed ID: 20039683
    [Abstract] [Full Text] [Related]

  • 18. Structure proof and synthesis of kotalanol and de-O-sulfonated kotalanol, glycosidase inhibitors isolated from an herbal remedy for the treatment of type-2 diabetes.
    Jayakanthan K, Mohan S, Pinto BM.
    J Am Chem Soc; 2009 Apr 22; 131(15):5621-6. PubMed ID: 19331410
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of a biologically active isomer of kotalanol, a naturally occurring glucosidase inhibitor.
    Eskandari R, Jayakanthan K, Kuntz DA, Rose DR, Pinto BM.
    Bioorg Med Chem; 2010 Apr 15; 18(8):2829-35. PubMed ID: 20363144
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of heteroanalogues of kotalanol and de-O-sulfonated kotalanol.
    Mohan S, Jayakanthan K, Nasi R, Kuntz DA, Rose DR, Pinto BM.
    Org Lett; 2010 Mar 05; 12(5):1088-91. PubMed ID: 20143790
    [Abstract] [Full Text] [Related]

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