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Journal Abstract Search

555 related items for PubMed ID: 22138155

  • 1. FLZ protects dopaminergic neuron through activating protein kinase B/mammalian target of rapamycin pathway and inhibiting RTP801 expression in Parkinson's disease models.
    Bao XQ, Kong XC, Qian C, Zhang D.
    Neuroscience; 2012 Jan 27; 202():396-404. PubMed ID: 22138155
    [Abstract] [Full Text] [Related]

  • 2. Squamosamide derivative FLZ protected dopaminergic neuron by activating Akt signaling pathway in 6-OHDA-induced in vivo and in vitro Parkinson's disease models.
    Bao XQ, Kong XC, Kong LB, Wu LY, Sun H, Zhang D.
    Brain Res; 2014 Feb 14; 1547():49-57. PubMed ID: 24384139
    [Abstract] [Full Text] [Related]

  • 3. Squamosamide derivative FLZ protected tyrosine hydroxylase function in a chronic MPTP/probenecid mouse model of Parkinson's disease.
    Bao XQ, Wu LY, Wang XL, Sun H, Zhang D.
    Naunyn Schmiedebergs Arch Pharmacol; 2015 May 14; 388(5):549-56. PubMed ID: 25678053
    [Abstract] [Full Text] [Related]

  • 4. Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways.
    Chen WF, Wu L, Du ZR, Chen L, Xu AL, Chen XH, Teng JJ, Wong MS.
    Phytomedicine; 2017 Feb 15; 25():93-99. PubMed ID: 28190476
    [Abstract] [Full Text] [Related]

  • 5. Neuroprotection by Paeoniflorin in the MPTP mouse model of Parkinson's disease.
    Zheng M, Liu C, Fan Y, Yan P, Shi D, Zhang Y.
    Neuropharmacology; 2017 Apr 15; 116():412-420. PubMed ID: 28093210
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of Src tyrosine kinase activity by squamosamide derivative FLZ attenuates neuroinflammation in both in vivo and in vitro Parkinson's disease models.
    Tai W, Ye X, Bao X, Zhao B, Wang X, Zhang D.
    Neuropharmacology; 2013 Dec 15; 75():201-12. PubMed ID: 23916477
    [Abstract] [Full Text] [Related]

  • 7. Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease.
    Zhang L, Huang L, Chen L, Hao D, Chen J.
    Toxicol Lett; 2013 Oct 24; 222(2):155-63. PubMed ID: 23911879
    [Abstract] [Full Text] [Related]

  • 8. Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.
    Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.
    J Neuroinflammation; 2008 May 28; 5():21. PubMed ID: 18507839
    [Abstract] [Full Text] [Related]

  • 9. Neuroprotective Effects of the DPP4 Inhibitor Vildagliptin in In Vivo and In Vitro Models of Parkinson's Disease.
    Pariyar R, Bastola T, Lee DH, Seo J.
    Int J Mol Sci; 2022 Feb 21; 23(4):. PubMed ID: 35216503
    [Abstract] [Full Text] [Related]

  • 10. IGF-1 inhibits MPTP/MPP+-induced autophagy on dopaminergic neurons through the IGF-1R/PI3K-Akt-mTOR pathway and GPER.
    Wang XW, Yuan LJ, Yang Y, Zhang M, Chen WF.
    Am J Physiol Endocrinol Metab; 2020 Oct 01; 319(4):E734-E743. PubMed ID: 32865008
    [Abstract] [Full Text] [Related]

  • 11. Role of the Akt/GSK-3β/CRMP-2 pathway in axon degeneration of dopaminergic neurons resulting from MPP+ toxicity.
    Fang W, Gao G, Zhao H, Xia Y, Guo X, Li N, Li Y, Yang Y, Chen L, Wang Q, Li L.
    Brain Res; 2015 Mar 30; 1602():9-19. PubMed ID: 25150591
    [Abstract] [Full Text] [Related]

  • 12. Metformin lowers α-synuclein phosphorylation and upregulates neurotrophic factor in the MPTP mouse model of Parkinson's disease.
    Katila N, Bhurtel S, Shadfar S, Srivastav S, Neupane S, Ojha U, Jeong GS, Choi DY.
    Neuropharmacology; 2017 Oct 30; 125():396-407. PubMed ID: 28807678
    [Abstract] [Full Text] [Related]

  • 13. Amentoflavone protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through PI3K/Akt and ERK signaling pathways.
    Cao Q, Qin L, Huang F, Wang X, Yang L, Shi H, Wu H, Zhang B, Chen Z, Wu X.
    Toxicol Appl Pharmacol; 2017 Mar 15; 319():80-90. PubMed ID: 28185818
    [Abstract] [Full Text] [Related]

  • 14. Phosphatidylinositol 3-kinase/Akt signaling pathway mediates acupuncture-induced dopaminergic neuron protection and motor function improvement in a mouse model of Parkinson's disease.
    Kim SN, Kim ST, Doo AR, Park JY, Moon W, Chae Y, Yin CS, Lee H, Park HJ.
    Int J Neurosci; 2011 Oct 15; 121(10):562-9. PubMed ID: 21770712
    [Abstract] [Full Text] [Related]

  • 15. Total glucosides of paeony (TGP) extracted from Radix Paeoniae Alba exerts neuroprotective effects in MPTP-induced experimental parkinsonism by regulating the cAMP/PKA/CREB signaling pathway.
    Zheng M, Liu C, Fan Y, Shi D, Jian W.
    J Ethnopharmacol; 2019 Dec 05; 245():112182. PubMed ID: 31445131
    [Abstract] [Full Text] [Related]

  • 16. Harpagoside attenuates MPTP/MPP⁺ induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor.
    Sun X, Xiong Z, Zhang Y, Meng Y, Xu G, Xia Z, Li J, Zhang R, Ke Z, Xia Z, Hu Y.
    J Neurochem; 2012 Mar 05; 120(6):1072-83. PubMed ID: 22192054
    [Abstract] [Full Text] [Related]

  • 17. RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.
    Malagelada C, Ryu EJ, Biswas SC, Jackson-Lewis V, Greene LA.
    J Neurosci; 2006 Sep 27; 26(39):9996-10005. PubMed ID: 17005863
    [Abstract] [Full Text] [Related]

  • 18. Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease through PI3K/Akt signaling pathway.
    Hu M, Li F, Wang W.
    Drug Des Devel Ther; 2018 Sep 27; 12():565-573. PubMed ID: 29588573
    [Abstract] [Full Text] [Related]

  • 19. Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway.
    Liu Y, Geng L, Zhang J, Wang J, Zhang Q, Duan D, Zhang Q.
    Mar Drugs; 2018 Mar 06; 16(3):. PubMed ID: 29509717
    [Abstract] [Full Text] [Related]

  • 20. Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice.
    Guo C, Hao LJ, Yang ZH, Chai R, Zhang S, Gu Y, Gao HL, Zhong ML, Wang T, Li JY, Wang ZY.
    Exp Neurol; 2016 Jun 06; 280():13-23. PubMed ID: 26996132
    [Abstract] [Full Text] [Related]

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