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Journal Abstract Search

286 related items for PubMed ID: 22140443

  • 1. Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.
    Alvino CL, Ong SC, McNeil KA, Delaine C, Booker GW, Wallace JC, Forbes BE.
    PLoS One; 2011; 6(11):e27488. PubMed ID: 22140443
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  • 6. An investigation of the ligand binding properties and negative cooperativity of soluble insulin-like growth factor receptors.
    Surinya KH, Forbes BE, Occhiodoro F, Booker GW, Francis GL, Siddle K, Wallace JC, Cosgrove LJ.
    J Biol Chem; 2008 Feb 29; 283(9):5355-63. PubMed ID: 18056713
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  • 7. Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
    Macháčková K, Mlčochová K, Potalitsyn P, Hanková K, Socha O, Buděšínský M, Muždalo A, Lepšík M, Černeková M, Radosavljević J, Fábry M, Mitrová K, Chrudinová M, Lin J, Yurenko Y, Hobza P, Selicharová I, Žáková L, Jiráček J.
    J Biol Chem; 2019 Nov 15; 294(46):17371-17382. PubMed ID: 31558604
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  • 8. Determinants of IGF-II influencing stability, receptor binding and activation.
    Blyth A, Ortiz M, Merriman A, Delaine C, Forbes B.
    Sci Rep; 2022 Mar 18; 12(1):4695. PubMed ID: 35304516
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  • 9. Insulin-Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity.
    Křížková K, Chrudinová M, Povalová A, Selicharová I, Collinsová M, Vaněk V, Brzozowski AM, Jiráček J, Žáková L.
    Biochemistry; 2016 May 31; 55(21):2903-13. PubMed ID: 27171135
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  • 10. Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.
    Denley A, Bonython ER, Booker GW, Cosgrove LJ, Forbes BE, Ward CW, Wallace JC.
    Mol Endocrinol; 2004 Oct 31; 18(10):2502-12. PubMed ID: 15205474
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  • 12. Elucidating the Activation Mechanism of the Insulin-Family Proteins with Molecular Dynamics Simulations.
    Papaioannou A, Kuyucak S, Kuncic Z.
    PLoS One; 2016 Oct 31; 11(8):e0161459. PubMed ID: 27548502
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  • 13. Insulin-like growth factor type 1 receptor and insulin receptor isoform expression and signaling in mammary epithelial cells.
    Rowzee AM, Ludwig DL, Wood TL.
    Endocrinology; 2009 Aug 31; 150(8):3611-9. PubMed ID: 19406949
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  • 14. Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.
    Gauguin L, Klaproth B, Sajid W, Andersen AS, McNeil KA, Forbes BE, De Meyts P.
    J Biol Chem; 2008 Feb 01; 283(5):2604-13. PubMed ID: 18048361
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  • 15. Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A.
    Sacco A, Morcavallo A, Pandini G, Vigneri R, Belfiore A.
    Endocrinology; 2009 Aug 01; 150(8):3594-602. PubMed ID: 19443570
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  • 20. Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
    Whitten AE, Smith BJ, Menting JG, Margetts MB, McKern NM, Lovrecz GO, Adams TE, Richards K, Bentley JD, Trewhella J, Ward CW, Lawrence MC.
    J Mol Biol; 2009 Dec 18; 394(5):878-92. PubMed ID: 19835884
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