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269 related items for PubMed ID: 22142144
1. The third extracellular loop of the human calcitonin receptor-like receptor is crucial for the activation of adrenomedullin signalling. Kuwasako K, Hay DL, Nagata S, Hikosaka T, Kitamura K, Kato J. Br J Pharmacol; 2012 May; 166(1):137-50. PubMed ID: 22142144 [Abstract] [Full Text] [Related]
2. Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology. Watkins HA, Walker CS, Ly KN, Bailey RJ, Barwell J, Poyner DR, Hay DL. Br J Pharmacol; 2014 Feb; 171(3):772-88. PubMed ID: 24199627 [Abstract] [Full Text] [Related]
3. Cardiovascular effects of exogenous adrenomedullin and CGRP in Ramp and Calcrl deficient mice. Pawlak JB, Wetzel-Strong SE, Dunn MK, Caron KM. Peptides; 2017 Feb; 88():1-7. PubMed ID: 27940069 [Abstract] [Full Text] [Related]
4. Structure-function analyses reveal a triple β-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design. Roehrkasse AM, Booe JM, Lee SM, Warner ML, Pioszak AA. J Biol Chem; 2018 Oct 12; 293(41):15840-15854. PubMed ID: 30139742 [Abstract] [Full Text] [Related]
5. Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties. Watkins HA, Chakravarthy M, Abhayawardana RS, Gingell JJ, Garelja M, Pardamwar M, McElhinney JM, Lathbridge A, Constantine A, Harris PW, Yuen TY, Brimble MA, Barwell J, Poyner DR, Woolley MJ, Conner AC, Pioszak AA, Reynolds CA, Hay DL. J Biol Chem; 2016 May 27; 291(22):11657-75. PubMed ID: 27013657 [Abstract] [Full Text] [Related]
6. Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists. Booe JM, Warner ML, Roehrkasse AM, Hay DL, Pioszak AA. Mol Pharmacol; 2018 Apr 27; 93(4):355-367. PubMed ID: 29363552 [Abstract] [Full Text] [Related]
7. Ligand-induced internalization, recycling, and resensitization of adrenomedullin receptors depend not on CLR or RAMP alone but on the receptor complex as a whole. Nag K, Sultana N, Kato A, Dranik A, Nakamura N, Kutsuzawa K, Hirose S, Akaike T. Gen Comp Endocrinol; 2015 Feb 01; 212():156-62. PubMed ID: 24815888 [Abstract] [Full Text] [Related]
8. Structure-function analysis of amino acid 74 of human RAMP1 and RAMP3 and its role in peptide interactions with adrenomedullin and calcitonin gene-related peptide receptors. Qi T, Ly K, Poyner DR, Christopoulos G, Sexton PM, Hay DL. Peptides; 2011 May 01; 32(5):1060-7. PubMed ID: 21402116 [Abstract] [Full Text] [Related]
9. Shared and separate functions of the RAMP-based adrenomedullin receptors. Kuwasako K, Kitamura K, Nagata S, Hikosaka T, Takei Y, Kato J. Peptides; 2011 Jul 01; 32(7):1540-50. PubMed ID: 21645567 [Abstract] [Full Text] [Related]
10. Characterization of the single transmembrane domain of human receptor activity-modifying protein 3 in adrenomedullin receptor internalization. Kuwasako K, Kitamura K, Nagata S, Nozaki N, Kato J. Biochem Biophys Res Commun; 2012 Apr 13; 420(3):582-7. PubMed ID: 22445753 [Abstract] [Full Text] [Related]
11. Functions of third extracellular loop and helix 8 of Family B GPCRs complexed with RAMPs and characteristics of their receptor trafficking. Kuwasako K, Hay DL, Nagata S, Murakami M, Kitamura K, Kato J. Curr Protein Pept Sci; 2013 Aug 13; 14(5):416-28. PubMed ID: 23745705 [Abstract] [Full Text] [Related]
12. Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins. Moad HE, Pioszak AA. Protein Sci; 2013 Dec 13; 22(12):1775-85. PubMed ID: 24115156 [Abstract] [Full Text] [Related]
13. Differential expression of components of the CGRP-receptor family in human coronary and human middle meningeal arteries: functional implications. de Vries T, Schutter D, van den Bogaerdt A, Vincent A, Dammers R, Danser AHJ, MaassenVanDenBrink A. J Headache Pain; 2024 Oct 10; 25(1):176. PubMed ID: 39390360 [Abstract] [Full Text] [Related]
15. Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin2 G protein-coupled receptor. Babin KM, Karim JA, Gordon PH, Lennon J, Dickson A, Pioszak AA. J Biol Chem; 2023 Jun 10; 299(6):104785. PubMed ID: 37146967 [Abstract] [Full Text] [Related]
19. Regulation of cardiovascular development and homeostasis by the adrenomedullin-RAMP system. Shindo T, Tanaka M, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Sakurai T. Peptides; 2019 Jan 18; 111():55-61. PubMed ID: 29689347 [Abstract] [Full Text] [Related]