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1052 related items for PubMed ID: 22142471

  • 1. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
    Rojo AI, Medina-Campos ON, Rada P, Zúñiga-Toalá A, López-Gazcón A, Espada S, Pedraza-Chaverri J, Cuadrado A.
    Free Radic Biol Med; 2012 Jan 15; 52(2):473-87. PubMed ID: 22142471
    [Abstract] [Full Text] [Related]

  • 2. Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3.
    Hayes JD, Chowdhry S, Dinkova-Kostova AT, Sutherland C.
    Biochem Soc Trans; 2015 Aug 15; 43(4):611-20. PubMed ID: 26551701
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  • 6. Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.
    Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ.
    Arch Biochem Biophys; 2010 Sep 01; 501(1):142-50. PubMed ID: 20558128
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  • 7. The antioxidative potential of farrerol occurs via the activation of Nrf2 mediated HO-1 signaling in RAW 264.7 cells.
    Ci X, Lv H, Wang L, Wang X, Peng L, Qin FX, Cheng G.
    Chem Biol Interact; 2015 Sep 05; 239():192-9. PubMed ID: 26111761
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  • 8. The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation.
    Xing HY, Cai YQ, Wang XF, Wang LL, Li P, Wang GY, Chen JH.
    PLoS One; 2015 Sep 05; 10(12):e0145183. PubMed ID: 26674355
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  • 9. Functional dissection of Nrf2-dependent phase II genes in vascular inflammation and endotoxic injury using Keap1 siRNA.
    Kim JH, Choi YK, Lee KS, Cho DH, Baek YY, Lee DK, Ha KS, Choe J, Won MH, Jeoung D, Lee H, Kwon YG, Kim YM.
    Free Radic Biol Med; 2012 Aug 01; 53(3):629-40. PubMed ID: 22609006
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  • 10. Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP.
    Cuadrado A.
    Free Radic Biol Med; 2015 Nov 01; 88(Pt B):147-157. PubMed ID: 25937177
    [Abstract] [Full Text] [Related]

  • 11. Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling.
    Li L, Dong H, Song E, Xu X, Liu L, Song Y.
    Chem Biol Interact; 2014 Feb 25; 209():56-67. PubMed ID: 24361488
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  • 12. GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress.
    Rojo AI, Sagarra MR, Cuadrado A.
    J Neurochem; 2008 Apr 25; 105(1):192-202. PubMed ID: 18005231
    [Abstract] [Full Text] [Related]

  • 13. Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress.
    Guzmán-Beltrán S, Espada S, Orozco-Ibarra M, Pedraza-Chaverri J, Cuadrado A.
    Neurosci Lett; 2008 Dec 12; 447(2-3):167-71. PubMed ID: 18852027
    [Abstract] [Full Text] [Related]

  • 14. Auranofin, a gold(I)-containing antirheumatic compound, activates Keap1/Nrf2 signaling via Rac1/iNOS signal and mitogen-activated protein kinase activation.
    Kim NH, Oh MK, Park HJ, Kim IS.
    J Pharmacol Sci; 2010 Dec 12; 113(3):246-54. PubMed ID: 20647686
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  • 15. Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2.
    Salazar M, Rojo AI, Velasco D, de Sagarra RM, Cuadrado A.
    J Biol Chem; 2006 May 26; 281(21):14841-51. PubMed ID: 16551619
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
    Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN.
    Mol Cancer Ther; 2006 Aug 26; 5(8):1918-26. PubMed ID: 16928811
    [Abstract] [Full Text] [Related]

  • 17. Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.
    Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T.
    J Pharmacol Exp Ther; 2009 Oct 26; 331(1):255-64. PubMed ID: 19628634
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  • 18. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia.
    Chiou YS, Huang Q, Ho CT, Wang YJ, Pan MH.
    Free Radic Biol Med; 2016 May 26; 94():1-16. PubMed ID: 26878775
    [Abstract] [Full Text] [Related]

  • 19. Isoflavone biochanin A, a novel nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element activator, protects against oxidative damage in HepG2 cells.
    Liang F, Cao W, Huang Y, Fang Y, Cheng Y, Pan S, Xu X.
    Biofactors; 2019 Jul 26; 45(4):563-574. PubMed ID: 31131946
    [Abstract] [Full Text] [Related]

  • 20. Activation of Nrf2 in defense against cadmium-induced oxidative stress.
    He X, Chen MG, Ma Q.
    Chem Res Toxicol; 2008 Jul 26; 21(7):1375-83. PubMed ID: 18512965
    [Abstract] [Full Text] [Related]

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