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Journal Abstract Search

253 related items for PubMed ID: 22147709

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  • 6. Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
    Coopman K, Wallis R, Robb G, Brown AJ, Wilkinson GF, Timms D, Willars GB.
    Mol Endocrinol; 2011 Oct; 25(10):1804-18. PubMed ID: 21868452
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  • 7. Comparative effects of the endogenous agonist glucagon-like peptide-1 (GLP-1)-(7-36) amide and the small-molecule ago-allosteric agent "compound 2" at the GLP-1 receptor.
    Coopman K, Huang Y, Johnston N, Bradley SJ, Wilkinson GF, Willars GB.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):795-808. PubMed ID: 20507928
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  • 8. Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.
    Baggio LL, Huang Q, Brown TJ, Drucker DJ.
    Gastroenterology; 2004 Aug 01; 127(2):546-58. PubMed ID: 15300587
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  • 9. The major determinant of exendin-4/glucagon-like peptide 1 differential affinity at the rat glucagon-like peptide 1 receptor N-terminal domain is a hydrogen bond from SER-32 of exendin-4.
    Mann RJ, Nasr NE, Sinfield JK, Paci E, Donnelly D.
    Br J Pharmacol; 2010 Aug 01; 160(8):1973-84. PubMed ID: 20649595
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  • 10. Allosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptor.
    Li N, Lu J, Willars GB.
    PLoS One; 2012 Aug 01; 7(10):e47936. PubMed ID: 23094100
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  • 11. Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket.
    Mann RJ, Al-Sabah S, de Maturana RL, Sinfield JK, Donnelly D.
    Peptides; 2010 Dec 01; 31(12):2289-93. PubMed ID: 20869417
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  • 12. Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery.
    Harikumar KG, Wootten D, Pinon DI, Koole C, Ball AM, Furness SG, Graham B, Dong M, Christopoulos A, Miller LJ, Sexton PM.
    Proc Natl Acad Sci U S A; 2012 Nov 06; 109(45):18607-12. PubMed ID: 23091034
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  • 13. Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain.
    Runge S, Thøgersen H, Madsen K, Lau J, Rudolph R.
    J Biol Chem; 2008 Apr 25; 283(17):11340-7. PubMed ID: 18287102
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  • 14. Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain.
    West GM, Willard FS, Sloop KW, Showalter AD, Pascal BD, Griffin PR.
    PLoS One; 2014 Apr 25; 9(9):e105683. PubMed ID: 25180755
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  • 15. A small molecule ligand of the glucagon-like peptide 1 receptor targets its amino-terminal hormone binding domain.
    Tibaduiza EC, Chen C, Beinborn M.
    J Biol Chem; 2001 Oct 12; 276(41):37787-93. PubMed ID: 11498540
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  • 16. Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP.
    Chepurny OG, Matsoukas MT, Liapakis G, Leech CA, Milliken BT, Doyle RP, Holz GG.
    J Biol Chem; 2019 Mar 08; 294(10):3514-3531. PubMed ID: 30622136
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  • 17. Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors.
    Yuliantie E, Darbalaei S, Dai A, Zhao P, Yang D, Sexton PM, Wang MW, Wootten D.
    Biochem Pharmacol; 2020 Jul 08; 177():114001. PubMed ID: 32360365
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