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Journal Abstract Search

155 related items for PubMed ID: 22148880

  • 1. Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin.
    Perić M, Fajdetić A, Rupčić R, Alihodžić S, Ziher D, Bukvić Krajačić M, Smith KS, Ivezić-Schönfeld Z, Padovan J, Landek G, Jelić D, Hutinec A, Mesić M, Ager A, Ellis WY, Milhous WK, Ohrt C, Spaventi R.
    J Med Chem; 2012 Feb 09; 55(3):1389-401. PubMed ID: 22148880
    [Abstract] [Full Text] [Related]

  • 2. Novel hybrid molecules based on 15-membered azalide as potential antimalarial agents.
    Starčević K, Pešić D, Toplak A, Landek G, Alihodžić S, Herreros E, Ferrer S, Spaventi R, Perić M.
    Eur J Med Chem; 2012 Mar 09; 49():365-78. PubMed ID: 22321992
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides.
    Pešić D, Starčević K, Toplak A, Herreros E, Vidal J, Almela MJ, Jelić D, Alihodžić S, Spaventi R, Perić M.
    J Med Chem; 2012 Apr 12; 55(7):3216-27. PubMed ID: 22380766
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, structure-activity relationship, and antimalarial activity of ureas and thioureas of 15-membered azalides.
    Bukvić Krajačić M, Perić M, Smith KS, Schönfeld ZI, Žiher D, Fajdetić A, Kujundžić N, Schönfeld W, Landek G, Padovan J, Jelić D, Ager A, Milhous WK, Ellis W, Spaventi R, Ohrt C.
    J Med Chem; 2011 May 26; 54(10):3595-605. PubMed ID: 21476508
    [Abstract] [Full Text] [Related]

  • 5. Chemobiosynthesis of new antimalarial macrolides.
    Goodman CD, Useglio M, Peirú S, Labadie GR, McFadden GI, Rodríguez E, Gramajo H.
    Antimicrob Agents Chemother; 2013 Feb 26; 57(2):907-13. PubMed ID: 23208707
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
    O'Neill PM, Shone AE, Stanford D, Nixon G, Asadollahy E, Park BK, Maggs JL, Roberts P, Stocks PA, Biagini G, Bray PG, Davies J, Berry N, Hall C, Rimmer K, Winstanley PA, Hindley S, Bambal RB, Davis CB, Bates M, Gresham SL, Brigandi RA, Gomez-de-Las-Heras FM, Gargallo DV, Parapini S, Vivas L, Lander H, Taramelli D, Ward SA.
    J Med Chem; 2009 Apr 09; 52(7):1828-44. PubMed ID: 19284751
    [Abstract] [Full Text] [Related]

  • 7. Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives.
    Shiraki H, Kozar MP, Melendez V, Hudson TH, Ohrt C, Magill AJ, Lin AJ.
    J Med Chem; 2011 Jan 13; 54(1):131-42. PubMed ID: 21141892
    [Abstract] [Full Text] [Related]

  • 8. Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
    Gemma S, Camodeca C, Sanna Coccone S, Joshi BP, Bernetti M, Moretti V, Brogi S, Bonache de Marcos MC, Savini L, Taramelli D, Basilico N, Parapini S, Rottmann M, Brun R, Lamponi S, Caccia S, Guiso G, Summers RL, Martin RE, Saponara S, Gorelli B, Novellino E, Campiani G, Butini S.
    J Med Chem; 2012 Aug 09; 55(15):6948-67. PubMed ID: 22783984
    [Abstract] [Full Text] [Related]

  • 9. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro.
    Nakornchai S, Konthiang P.
    Acta Trop; 2006 Dec 09; 100(3):185-91. PubMed ID: 17126280
    [Abstract] [Full Text] [Related]

  • 10. Trioxaferroquines as new hybrid antimalarial drugs.
    Bellot F, Coslédan F, Vendier L, Brocard J, Meunier B, Robert A.
    J Med Chem; 2010 May 27; 53(10):4103-9. PubMed ID: 20443628
    [Abstract] [Full Text] [Related]

  • 11. An automated, polymer-assisted strategy for the preparation of urea and thiourea derivatives of 15-membered azalides as potential antimalarial chemotherapeutics.
    Hutinec A, Rupčić R, Ziher D, Smith KS, Milhous W, Ellis W, Ohrt C, Schönfeld ZI.
    Bioorg Med Chem; 2011 Mar 01; 19(5):1692-701. PubMed ID: 21316974
    [Abstract] [Full Text] [Related]

  • 12. Antimalarial pyrido[1,2-a]benzimidazoles.
    Ndakala AJ, Gessner RK, Gitari PW, October N, White KL, Hudson A, Fakorede F, Shackleford DM, Kaiser M, Yeates C, Charman SA, Chibale K.
    J Med Chem; 2011 Jul 14; 54(13):4581-9. PubMed ID: 21644541
    [Abstract] [Full Text] [Related]

  • 13. Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials.
    O'Neill PM, Mukhtar A, Stocks PA, Randle LE, Hindley S, Ward SA, Storr RC, Bickley JF, O'Neil IA, Maggs JL, Hughes RH, Winstanley PA, Bray PG, Park BK.
    J Med Chem; 2003 Nov 06; 46(23):4933-45. PubMed ID: 14584944
    [Abstract] [Full Text] [Related]

  • 14. Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline.
    Sparatore A, Basilico N, Casagrande M, Parapini S, Taramelli D, Brun R, Wittlin S, Sparatore F.
    Bioorg Med Chem Lett; 2008 Jul 01; 18(13):3737-40. PubMed ID: 18538567
    [Abstract] [Full Text] [Related]

  • 15. Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
    O'Neill PM, Park BK, Shone AE, Maggs JL, Roberts P, Stocks PA, Biagini GA, Bray PG, Gibbons P, Berry N, Winstanley PA, Mukhtar A, Bonar-Law R, Hindley S, Bambal RB, Davis CB, Bates M, Hart TK, Gresham SL, Lawrence RM, Brigandi RA, Gomez-delas-Heras FM, Gargallo DV, Ward SA.
    J Med Chem; 2009 Mar 12; 52(5):1408-15. PubMed ID: 19222165
    [Abstract] [Full Text] [Related]

  • 16. In-vitro antimalarial activity of azithromycin against chloroquine sensitive and chloroquine resistant Plasmodium falciparum.
    Biswas S.
    J Postgrad Med; 2001 Mar 12; 47(4):240-3. PubMed ID: 11832638
    [Abstract] [Full Text] [Related]

  • 17. Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.
    Friebolin W, Jannack B, Wenzel N, Furrer J, Oeser T, Sanchez CP, Lanzer M, Yardley V, Becker K, Davioud-Charvet E.
    J Med Chem; 2008 Mar 13; 51(5):1260-77. PubMed ID: 18260613
    [Abstract] [Full Text] [Related]

  • 18. Novel orally active antimalarial thiazoles.
    González Cabrera D, Douelle F, Feng TS, Nchinda AT, Younis Y, White KL, Wu Q, Ryan E, Burrows JN, Waterson D, Witty MJ, Wittlin S, Charman SA, Chibale K.
    J Med Chem; 2011 Nov 10; 54(21):7713-9. PubMed ID: 21966980
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities.
    Madrid PB, Sherrill J, Liou AP, Weisman JL, Derisi JL, Guy RK.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1015-8. PubMed ID: 15686903
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and antimalarial activity of side chain modified 4-aminoquinoline derivatives.
    Solomon VR, Haq W, Srivastava K, Puri SK, Katti SB.
    J Med Chem; 2007 Jan 25; 50(2):394-8. PubMed ID: 17228883
    [Abstract] [Full Text] [Related]

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