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160 related items for PubMed ID: 22157618

  • 1. Early microglial activation precedes neuronal loss in the brain of the Cstb-/- mouse model of progressive myoclonus epilepsy, EPM1.
    Tegelberg S, Kopra O, Joensuu T, Cooper JD, Lehesjoki AE.
    J Neuropathol Exp Neurol; 2012 Jan; 71(1):40-53. PubMed ID: 22157618
    [Abstract] [Full Text] [Related]

  • 2. Abnormal microglial activation in the Cstb(-/-) mouse, a model for progressive myoclonus epilepsy, EPM1.
    Okuneva O, Körber I, Li Z, Tian L, Joensuu T, Kopra O, Lehesjoki AE.
    Glia; 2015 Mar; 63(3):400-11. PubMed ID: 25327891
    [Abstract] [Full Text] [Related]

  • 3. Altered tryptophan metabolism in the brain of cystatin B-deficient mice: a model system for progressive myoclonus epilepsy.
    Vaarmann A, Kaasik A, Zharkovsky A.
    Epilepsia; 2006 Oct; 47(10):1650-4. PubMed ID: 17054687
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  • 4. White matter degeneration with Unverricht-Lundborg progressive myoclonus epilepsy: a translational diffusion-tensor imaging study in patients and cystatin B-deficient mice.
    Manninen O, Koskenkorva P, Lehtimäki KK, Hyppönen J, Könönen M, Laitinen T, Kalimo H, Kopra O, Kälviäinen R, Gröhn O, Lehesjoki AE, Vanninen R.
    Radiology; 2013 Oct; 269(1):232-9. PubMed ID: 23788720
    [Abstract] [Full Text] [Related]

  • 5. Molecular background of EPM1-Unverricht-Lundborg disease.
    Joensuu T, Lehesjoki AE, Kopra O.
    Epilepsia; 2008 Apr; 49(4):557-63. PubMed ID: 18028412
    [Abstract] [Full Text] [Related]

  • 6. Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy.
    Sierra-Torre V, Plaza-Zabala A, Bonifazi P, Abiega O, Díaz-Aparicio I, Tegelberg S, Lehesjoki AE, Valero J, Sierra A.
    Epilepsia; 2020 Nov; 61(11):2593-2608. PubMed ID: 32940364
    [Abstract] [Full Text] [Related]

  • 7. Gene-Expression Profiling Suggests Impaired Signaling via the Interferon Pathway in Cstb-/- Microglia.
    Körber I, Katayama S, Einarsdottir E, Krjutškov K, Hakala P, Kere J, Lehesjoki AE, Joensuu T.
    PLoS One; 2016 Nov; 11(6):e0158195. PubMed ID: 27355630
    [Abstract] [Full Text] [Related]

  • 8. A pathogenetic hypothesis of Unverricht-Lundborg disease onset and progression.
    Franceschetti S, Sancini G, Buzzi A, Zucchini S, Paradiso B, Magnaghi G, Frassoni C, Chikhladze M, Avanzini G, Simonato M.
    Neurobiol Dis; 2007 Mar; 25(3):675-85. PubMed ID: 17188503
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  • 10. Progressive volume loss and white matter degeneration in cstb-deficient mice: a diffusion tensor and longitudinal volumetry MRI study.
    Manninen O, Laitinen T, Lehtimäki KK, Tegelberg S, Lehesjoki AE, Gröhn O, Kopra O.
    PLoS One; 2014 Mar; 9(6):e90709. PubMed ID: 24603771
    [Abstract] [Full Text] [Related]

  • 11. Cystatin B: mutation detection, alternative splicing and expression in progressive myclonus epilepsy of Unverricht-Lundborg type (EPM1) patients.
    Joensuu T, Kuronen M, Alakurtti K, Tegelberg S, Hakala P, Aalto A, Huopaniemi L, Aula N, Michellucci R, Eriksson K, Lehesjoki AE.
    Eur J Hum Genet; 2007 Feb; 15(2):185-93. PubMed ID: 17003839
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  • 12. Unverricht-Lundborg disease.
    Crespel A, Ferlazzo E, Franceschetti S, Genton P, Gouider R, Kälviäinen R, Korja M, Lehtinen MK, Mervaala E, Simonato M, Vaarmann A.
    Epileptic Disord; 2016 Sep 01; 18(S2):28-37. PubMed ID: 27582036
    [Abstract] [Full Text] [Related]

  • 13. Severer phenotype in Unverricht-Lundborg disease (EPM1) patients compound heterozygous for the dodecamer repeat expansion and the c.202C>T mutation in the CSTB gene.
    Koskenkorva P, Hyppönen J, Aikiä M, Mervaala E, Kiviranta T, Eriksson K, Lehesjoki AE, Vanninen R, Kälviäinen R.
    Neurodegener Dis; 2011 Sep 01; 8(6):515-22. PubMed ID: 21757863
    [Abstract] [Full Text] [Related]

  • 14. Selective spatiotemporal patterns of glial activation and neuron loss in the sensory thalamocortical pathways of neuronal ceroid lipofuscinosis 8 mice.
    Kuronen M, Lehesjoki AE, Jalanko A, Cooper JD, Kopra O.
    Neurobiol Dis; 2012 Sep 01; 47(3):444-57. PubMed ID: 22569358
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  • 16. Loss of cortical GABA terminals in Unverricht-Lundborg disease.
    Buzzi A, Chikhladze M, Falcicchia C, Paradiso B, Lanza G, Soukupova M, Marti M, Morari M, Franceschetti S, Simonato M.
    Neurobiol Dis; 2012 Aug 01; 47(2):216-24. PubMed ID: 22538221
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  • 17. Neuropathological changes in a mouse model of progressive myoclonus epilepsy: cystatin B deficiency and Unverricht-Lundborg disease.
    Shannon P, Pennacchio LA, Houseweart MK, Minassian BA, Myers RM.
    J Neuropathol Exp Neurol; 2002 Dec 01; 61(12):1085-91. PubMed ID: 12484571
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  • 18. Thickened skull, scoliosis and other skeletal findings in Unverricht-Lundborg disease link cystatin B function to bone metabolism.
    Suoranta S, Manninen H, Koskenkorva P, Könönen M, Laitinen R, Lehesjoki AE, Kälviäinen R, Vanninen R.
    Bone; 2012 Dec 01; 51(6):1016-24. PubMed ID: 23010349
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  • 19. Refining the phenotype of Unverricht-Lundborg disease (EPM1): a population-wide Finnish study.
    Hyppönen J, Äikiä M, Joensuu T, Julkunen P, Danner N, Koskenkorva P, Vanninen R, Lehesjoki AE, Mervaala E, Kälviäinen R.
    Neurology; 2015 Apr 14; 84(15):1529-36. PubMed ID: 25770194
    [Abstract] [Full Text] [Related]

  • 20. Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation.
    Joensuu T, Tegelberg S, Reinmaa E, Segerstråle M, Hakala P, Pehkonen H, Korpi ER, Tyynelä J, Taira T, Hovatta I, Kopra O, Lehesjoki AE.
    PLoS One; 2014 Apr 14; 9(2):e89321. PubMed ID: 24586687
    [Abstract] [Full Text] [Related]

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