These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

539 related items for PubMed ID: 22158865

  • 1. Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.
    Patel AG, Flatten KS, Schneider PA, Dai NT, McDonald JS, Poirier GG, Kaufmann SH.
    J Biol Chem; 2012 Feb 03; 287(6):4198-210. PubMed ID: 22158865
    [Abstract] [Full Text] [Related]

  • 2.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 3. Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells.
    Zhang YW, Regairaz M, Seiler JA, Agama KK, Doroshow JH, Pommier Y.
    Nucleic Acids Res; 2011 May 03; 39(9):3607-20. PubMed ID: 21227924
    [Abstract] [Full Text] [Related]

  • 4. Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors.
    LoRusso PM, Li J, Burger A, Heilbrun LK, Sausville EA, Boerner SA, Smith D, Pilat MJ, Zhang J, Tolaney SM, Cleary JM, Chen AP, Rubinstein L, Boerner JL, Bowditch A, Cai D, Bell T, Wolanski A, Marrero AM, Zhang Y, Ji J, Ferry-Galow K, Kinders RJ, Parchment RE, Shapiro GI.
    Clin Cancer Res; 2016 Jul 01; 22(13):3227-37. PubMed ID: 26842236
    [Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.
    Smith LM, Willmore E, Austin CA, Curtin NJ.
    Clin Cancer Res; 2005 Dec 01; 11(23):8449-57. PubMed ID: 16322308
    [Abstract] [Full Text] [Related]

  • 7.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 8. Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.
    Ghosh R, Roy S, Kamyab J, Danzter F, Franco S.
    DNA Repair (Amst); 2016 Sep 01; 45():56-62. PubMed ID: 27373144
    [Abstract] [Full Text] [Related]

  • 9. Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent.
    Nguyen D, Zajac-Kaye M, Rubinstein L, Voeller D, Tomaszewski JE, Kummar S, Chen AP, Pommier Y, Doroshow JH, Yang SX.
    Cell Cycle; 2011 Dec 01; 10(23):4074-82. PubMed ID: 22101337
    [Abstract] [Full Text] [Related]

  • 10. Effect of p53 activity on the sensitivity of human glioblastoma cells to PARP-1 inhibitor in combination with topoisomerase I inhibitor or radiation.
    Sabbatino F, Fusciello C, Somma D, Pacelli R, Poudel R, Pepin D, Leonardi A, Carlomagno C, Della Vittoria Scarpati G, Ferrone S, Pepe S.
    Cytometry A; 2014 Nov 01; 85(11):953-61. PubMed ID: 25182801
    [Abstract] [Full Text] [Related]

  • 11. Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
    Velagapudi UK, Rouleau-Turcotte É, Billur R, Shao X, Patil M, Black BE, Pascal JM, Talele TT.
    Biochem J; 2024 Mar 20; 481(6):437-460. PubMed ID: 38372302
    [Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15. E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.
    McGonigle S, Chen Z, Wu J, Chang P, Kolber-Simonds D, Ackermann K, Twine NC, Shie JL, Miu JT, Huang KC, Moniz GA, Nomoto K.
    Oncotarget; 2015 Dec 01; 6(38):41307-23. PubMed ID: 26513298
    [Abstract] [Full Text] [Related]

  • 16. Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.
    Meyer-Ficca ML, Lonchar JD, Ihara M, Meistrich ML, Austin CA, Meyer RG.
    Biol Reprod; 2011 May 01; 84(5):900-9. PubMed ID: 21228215
    [Abstract] [Full Text] [Related]

  • 17. Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma.
    Chornenkyy Y, Agnihotri S, Yu M, Buczkowicz P, Rakopoulos P, Golbourn B, Garzia L, Siddaway R, Leung S, Rutka JT, Taylor MD, Dirks PB, Hawkins C.
    Mol Cancer Ther; 2015 Nov 01; 14(11):2560-8. PubMed ID: 26351319
    [Abstract] [Full Text] [Related]

  • 18. ATP modulates poly(ADP-ribose) polymerase-1-facilitated topoisomerase I-linked DNA religation in the presence of camptothecin.
    Park SY, Leung CH, Cheng YC.
    Mol Pharmacol; 2008 Jun 01; 73(6):1829-37. PubMed ID: 18349103
    [Abstract] [Full Text] [Related]

  • 19. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
    Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, Kyle S, Meuth M, Curtin NJ, Helleday T.
    Nature; 2005 Apr 14; 434(7035):913-7. PubMed ID: 15829966
    [Abstract] [Full Text] [Related]

  • 20. Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors.
    Hopkins TA, Shi Y, Rodriguez LE, Solomon LR, Donawho CK, DiGiammarino EL, Panchal SC, Wilsbacher JL, Gao W, Olson AM, Stolarik DF, Osterling DJ, Johnson EF, Maag D.
    Mol Cancer Res; 2015 Nov 14; 13(11):1465-77. PubMed ID: 26217019
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 27.