226 related items for PubMed ID: 22170725
1. Increased activation of the alternative "backdoor" pathway in patients with 21-hydroxylase deficiency: evidence from urinary steroid hormone analysis.
Kamrath C, Hochberg Z, Hartmann MF, Remer T, Wudy SA.
J Clin Endocrinol Metab; 2012 Mar; 97(3):E367-75. PubMed ID: 22170725
[Abstract] [Full Text] [Related]
2. The activities of 5α-reductase and 17,20-lyase determine the direction through androgen synthesis pathways in patients with 21-hydroxylase deficiency.
Kamrath C, Hartmann MF, Remer T, Wudy SA.
Steroids; 2012 Nov; 77(13):1391-7. PubMed ID: 22951291
[Abstract] [Full Text] [Related]
3. Urine steroid hormone profile analysis in cytochrome P450 oxidoreductase deficiency: implication for the backdoor pathway to dihydrotestosterone.
Homma K, Hasegawa T, Nagai T, Adachi M, Horikawa R, Fujiwara I, Tajima T, Takeda R, Fukami M, Ogata T.
J Clin Endocrinol Metab; 2006 Jul; 91(7):2643-9. PubMed ID: 16608896
[Abstract] [Full Text] [Related]
4. Androgen synthesis in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Kamrath C, Hartmann MF, Wudy SA.
Horm Metab Res; 2013 Feb; 45(2):86-91. PubMed ID: 23345132
[Abstract] [Full Text] [Related]
5. CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway.
van Rooyen D, Yadav R, Scott EE, Swart AC.
J Steroid Biochem Mol Biol; 2020 May; 199():105614. PubMed ID: 32007561
[Abstract] [Full Text] [Related]
6. Androgen biosynthesis during minipuberty favors the backdoor pathway over the classic pathway: Insights into enzyme activities and steroid fluxes in healthy infants during the first year of life from the urinary steroid metabolome.
Dhayat NA, Dick B, Frey BM, d'Uscio CH, Vogt B, Flück CE.
J Steroid Biochem Mol Biol; 2017 Jan; 165(Pt B):312-322. PubMed ID: 27471148
[Abstract] [Full Text] [Related]
7. Non-Classic Disorder of Adrenal Steroidogenesis and Clinical Dilemmas in 21-Hydroxylase Deficiency Combined with Backdoor Androgen Pathway. Mini-Review and Case Report.
Sumińska M, Bogusz-Górna K, Wegner D, Fichna M.
Int J Mol Sci; 2020 Jun 29; 21(13):. PubMed ID: 32610579
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8. Assessment of steroidogenesis and steroidogenic enzyme functions.
Luu-The V.
J Steroid Biochem Mol Biol; 2013 Sep 29; 137():176-82. PubMed ID: 23770321
[Abstract] [Full Text] [Related]
9. The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway.
van Rooyen D, Gent R, Barnard L, Swart AC.
J Steroid Biochem Mol Biol; 2018 Apr 29; 178():203-212. PubMed ID: 29277707
[Abstract] [Full Text] [Related]
10. The urinary steroidome of treated children with classic 21-hydroxylase deficiency.
Kamrath C, Wettstaedt L, Boettcher C, Hartmann MF, Wudy SA.
J Steroid Biochem Mol Biol; 2017 Jan 29; 165(Pt B):396-406. PubMed ID: 27544322
[Abstract] [Full Text] [Related]
11. The role of gonadotropins in testicular and adrenal androgen biosynthesis pathways-Insights from males with congenital hypogonadotropic hypogonadism on hCG/rFSH and on testosterone replacement.
Rohayem J, Zitzmann M, Laurentino S, Kliesch S, Nieschlag E, Holterhus PM, Kulle A.
Clin Endocrinol (Oxf); 2021 Jan 29; 94(1):90-101. PubMed ID: 32871622
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12. C19 and C21 5 beta/5 alpha metabolite ratios in subjects treated with the 5 alpha-reductase inhibitor finasteride: comparison of male pseudohermaphrodites with inherited 5 alpha-reductase deficiency.
Imperato-McGinley J, Shackleton C, Orlic S, Stoner E.
J Clin Endocrinol Metab; 1990 Mar 29; 70(3):777-82. PubMed ID: 1689740
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13. The 11β-hydroxyandrostenedione pathway and C11-oxy C21 backdoor pathway are active in benign prostatic hyperplasia yielding 11keto-testosterone and 11keto-progesterone.
du Toit T, Swart AC.
J Steroid Biochem Mol Biol; 2020 Feb 29; 196():105497. PubMed ID: 31626910
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14. Backdoor pathway for dihydrotestosterone biosynthesis: implications for normal and abnormal human sex development.
Fukami M, Homma K, Hasegawa T, Ogata T.
Dev Dyn; 2013 Apr 29; 242(4):320-9. PubMed ID: 23073980
[Abstract] [Full Text] [Related]
15. Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.
Jones CM, Mallappa A, Reisch N, Nikolaou N, Krone N, Hughes BA, O'Neil DM, Whitaker MJ, Tomlinson JW, Storbeck KH, Merke DP, Ross RJ, Arlt W.
J Clin Endocrinol Metab; 2017 Jun 01; 102(6):1797-1806. PubMed ID: 27845856
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16. Drug testing data from the 2007 Pan American Games: delta13C values of urinary androsterone, etiocholanolone and androstanediols determined by GC/C/IRMS.
Aguilera R, Chapman TE, Pereira H, Oliveira GC, Illanes RP, Fernandes TF, Azevedo DA, Neto FA.
J Steroid Biochem Mol Biol; 2009 Jul 01; 115(3-5):107-14. PubMed ID: 19428237
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17. Longitudinal serum and urine steroid metabolite profiling in a 46,XY infant with prenatally identified POR deficiency.
Ono H, Numakura C, Homma K, Hasegawa T, Tsutsumi S, Kato F, Fujisawa Y, Fukami M, Ogata T.
J Steroid Biochem Mol Biol; 2018 Apr 01; 178():177-184. PubMed ID: 29289577
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18. Limited value of serum steroid measurements in identification of mild form of 21-hydroxylase deficiency.
Török D, Halász Z, Garami M, Homoki J, Fekete G, Sólyom J.
Exp Clin Endocrinol Diabetes; 2003 Feb 01; 111(1):27-32. PubMed ID: 12605347
[Abstract] [Full Text] [Related]
19. Alternative (backdoor) androgen production and masculinization in the human fetus.
O'Shaughnessy PJ, Antignac JP, Le Bizec B, Morvan ML, Svechnikov K, Söder O, Savchuk I, Monteiro A, Soffientini U, Johnston ZC, Bellingham M, Hough D, Walker N, Filis P, Fowler PA.
PLoS Biol; 2019 Feb 01; 17(2):e3000002. PubMed ID: 30763313
[Abstract] [Full Text] [Related]
20. Metabolism of orally administered androstenedione in young men.
Leder BZ, Catlin DH, Longcope C, Ahrens B, Schoenfeld DA, Finkelstein JS.
J Clin Endocrinol Metab; 2001 Aug 01; 86(8):3654-8. PubMed ID: 11502792
[Abstract] [Full Text] [Related]
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