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Journal Abstract Search

189 related items for PubMed ID: 22185476

  • 1. Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure.
    Yamazaki Y, Tanaka K, Nicholson B, Deyanat-Yazdi G, Potts B, Yoshida T, Oda A, Kitagawa T, Orikasa S, Kiso Y, Yasui H, Akamatsu M, Chinen T, Usui T, Shinozaki Y, Yakushiji F, Miller BR, Neuteboom S, Palladino M, Kanoh K, Lloyd GK, Hayashi Y.
    J Med Chem; 2012 Feb 09; 55(3):1056-71. PubMed ID: 22185476
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents.
    Yamazaki Y, Sumikura M, Masuda Y, Hayashi Y, Yasui H, Kiso Y, Chinen T, Usui T, Yakushiji F, Potts B, Neuteboom S, Palladino M, Lloyd GK, Hayashi Y.
    Bioorg Med Chem; 2012 Jul 15; 20(14):4279-89. PubMed ID: 22727370
    [Abstract] [Full Text] [Related]

  • 3. Medicinal chemistry and chemical biology of diketopiperazine-type antimicrotubule and vascular-disrupting agents.
    Hayashi Y, Yamazaki-Nakamura Y, Yakushiji F.
    Chem Pharm Bull (Tokyo); 2013 Jul 15; 61(9):889-901. PubMed ID: 23995353
    [Abstract] [Full Text] [Related]

  • 4. Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.
    Yamazaki Y, Kohno K, Yasui H, Kiso Y, Akamatsu M, Nicholson B, Deyanat-Yazdi G, Neuteboom S, Potts B, Lloyd GK, Hayashi Y.
    Chembiochem; 2008 Dec 15; 9(18):3074-81. PubMed ID: 19012291
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.
    Jiang J, Sun B, Wang YY, Cui M, Zhang L, Cui CZ, Wang YF, Liu XG, Lou HX.
    Bioorg Med Chem; 2012 Apr 01; 20(7):2382-91. PubMed ID: 22365913
    [Abstract] [Full Text] [Related]

  • 6. Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure.
    Ding Z, Ma M, Zhong C, Wang S, Fu Z, Hou Y, Liu Y, Zhong L, Chu Y, Li F, Song C, Wang Y, Yang J, Li W.
    Bioorg Med Chem; 2020 Jan 01; 28(1):115186. PubMed ID: 31759826
    [Abstract] [Full Text] [Related]

  • 7. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
    Lee HY, Chang JY, Nien CY, Kuo CC, Shih KH, Wu CH, Chang CY, Lai WY, Liou JP.
    J Med Chem; 2011 Dec 22; 54(24):8517-25. PubMed ID: 22060033
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 9. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 10. Spiro[(dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)]-based cytotoxic agents: structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain.
    Gomez-Monterrey I, Campiglia P, Carotenuto A, Stiuso P, Bertamino A, Sala M, Aquino C, Grieco P, Morello S, Pinto A, Ianelli P, Novellino E.
    J Med Chem; 2008 May 22; 51(10):2924-32. PubMed ID: 18429610
    [Abstract] [Full Text] [Related]

  • 11. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 12. Design and Synthesis of Novel Phenylahistin Derivatives Based on Co-Crystal Structures as Potent Microtubule Inhibitors for Anti-Cancer Therapy.
    Ding Z, Li F, Xie L, Gu M, Li C, Liu C, Peng C, Li W.
    Mar Drugs; 2022 Nov 29; 20(12):. PubMed ID: 36547899
    [Abstract] [Full Text] [Related]

  • 13. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 14. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
    Leese MP, Jourdan FL, Gaukroger K, Mahon MF, Newman SP, Foster PA, Stengel C, Regis-Lydi S, Ferrandis E, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV.
    J Med Chem; 2008 Mar 13; 51(5):1295-308. PubMed ID: 18260615
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure.
    Fu Z, Hou Y, Ji C, Ma M, Tian Z, Deng M, Zhong L, Chu Y, Li W.
    Bioorg Med Chem; 2018 May 01; 26(8):2061-2072. PubMed ID: 29571653
    [Abstract] [Full Text] [Related]

  • 16. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer.
    Ding Z, Li F, Zhong C, Li F, Liu Y, Wang S, Zhao J, Li W.
    Bioorg Med Chem; 2020 May 15; 28(10):115435. PubMed ID: 32278711
    [Abstract] [Full Text] [Related]

  • 17. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2007 Nov 29; 50(24):6059-66. PubMed ID: 17973361
    [Abstract] [Full Text] [Related]

  • 18. Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents.
    Kim ND, Park ES, Kim YH, Moon SK, Lee SS, Ahn SK, Yu DY, No KT, Kim KH.
    Bioorg Med Chem; 2010 Oct 01; 18(19):7092-100. PubMed ID: 20810285
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.
    Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):147-52. PubMed ID: 23200248
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

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