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Journal Abstract Search

149 related items for PubMed ID: 22190695

  • 1. In vivo biliary clearance should be predicted by intrinsic biliary clearance in sandwich-cultured hepatocytes.
    Nakakariya M, Ono M, Amano N, Moriwaki T, Maeda K, Sugiyama Y.
    Drug Metab Dispos; 2012 Mar; 40(3):602-9. PubMed ID: 22190695
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  • 2. Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes.
    Fukuda H, Ohashi R, Tsuda-Tsukimoto M, Tamai I.
    Drug Metab Dispos; 2008 Jul; 36(7):1275-82. PubMed ID: 18388177
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  • 3. Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.
    Kotani N, Maeda K, Watanabe T, Hiramatsu M, Gong LK, Bi YA, Takezawa T, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2011 Sep; 39(9):1503-10. PubMed ID: 21673128
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  • 4. In vitro biliary clearance of angiotensin II receptor blockers and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in sandwich-cultured rat hepatocytes: comparison with in vivo biliary clearance.
    Abe K, Bridges AS, Yue W, Brouwer KL.
    J Pharmacol Exp Ther; 2008 Sep; 326(3):983-90. PubMed ID: 18574002
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  • 8. Improved extrapolation of hepatobiliary clearance from in vitro sandwich cultured rat hepatocytes through absolute quantification of hepatobiliary transporters.
    Li N, Singh P, Mandrell KM, Lai Y.
    Mol Pharm; 2010 Jun 07; 7(3):630-41. PubMed ID: 20438085
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  • 9. Estimation of transporters involved in the hepatobiliary transport of TA-0201CA using sandwich-cultured rat hepatocytes from normal and multidrug resistance-associated protein 2-deficient rats.
    Fukuda H, Ohashi R, Ohashi N, Yabuuchi H, Tamai I.
    Drug Metab Dispos; 2010 Sep 07; 38(9):1505-13. PubMed ID: 20538722
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  • 10. Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates.
    Chatterjee S, Bijsmans IT, van Mil SW, Augustijns P, Annaert P.
    Toxicol In Vitro; 2014 Mar 07; 28(2):218-30. PubMed ID: 24211540
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  • 12. Prediction of the hepatic and renal clearance of transporter substrates in rats using in vitro uptake experiments.
    Watanabe T, Maeda K, Kondo T, Nakayama H, Horita S, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2009 Jul 07; 37(7):1471-9. PubMed ID: 19364828
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  • 13. A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes.
    Riley RJ, McGinnity DF, Austin RP.
    Drug Metab Dispos; 2005 Sep 07; 33(9):1304-11. PubMed ID: 15932954
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  • 17. Assessment of biliary clearance in early drug discovery using sandwich-cultured hepatocyte model.
    Pan G, Boiselle C, Wang J.
    J Pharm Sci; 2012 May 07; 101(5):1898-908. PubMed ID: 22323123
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  • 19. Comparison of fresh and cryopreserved rat hepatocyte suspensions for the prediction of in vitro intrinsic clearance.
    Griffin SJ, Houston JB.
    Drug Metab Dispos; 2004 May 07; 32(5):552-8. PubMed ID: 15100178
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  • 20. Inhibition of biliary excretion of methotrexate by probenecid in rats: quantitative prediction of interaction from in vitro data.
    Ueda K, Kato Y, Komatsu K, Sugiyama Y.
    J Pharmacol Exp Ther; 2001 Jun 07; 297(3):1036-43. PubMed ID: 11356926
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