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143 related items for PubMed ID: 22245562

  • 1. Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP.
    Kroker KS, Rast G, Giovannini R, Marti A, Dorner-Ciossek C, Rosenbrock H.
    Neuropharmacology; 2012 Apr; 62(5-6):1964-74. PubMed ID: 22245562
    [Abstract] [Full Text] [Related]

  • 2. Restoring long-term potentiation impaired by amyloid-beta oligomers: comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists.
    Kroker KS, Moreth J, Kussmaul L, Rast G, Rosenbrock H.
    Brain Res Bull; 2013 Jul; 96():28-38. PubMed ID: 23639920
    [Abstract] [Full Text] [Related]

  • 3. The Novel Phosphodiesterase 9A Inhibitor BI 409306 Increases Cyclic Guanosine Monophosphate Levels in the Brain, Promotes Synaptic Plasticity, and Enhances Memory Function in Rodents.
    Rosenbrock H, Giovannini R, Schänzle G, Koros E, Runge F, Fuchs H, Marti A, Reymann KG, Schröder UH, Fedele E, Dorner-Ciossek C.
    J Pharmacol Exp Ther; 2019 Dec; 371(3):633-641. PubMed ID: 31578258
    [Abstract] [Full Text] [Related]

  • 4. The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents.
    van der Staay FJ, Rutten K, Bärfacker L, Devry J, Erb C, Heckroth H, Karthaus D, Tersteegen A, van Kampen M, Blokland A, Prickaerts J, Reymann KG, Schröder UH, Hendrix M.
    Neuropharmacology; 2008 Oct; 55(5):908-18. PubMed ID: 18674549
    [Abstract] [Full Text] [Related]

  • 5. PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition.
    Kroker KS, Mathis C, Marti A, Cassel JC, Rosenbrock H, Dorner-Ciossek C.
    Neurobiol Aging; 2014 Sep; 35(9):2072-8. PubMed ID: 24746365
    [Abstract] [Full Text] [Related]

  • 6. The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents.
    Hutson PH, Finger EN, Magliaro BC, Smith SM, Converso A, Sanderson PE, Mullins D, Hyde LA, Eschle BK, Turnbull Z, Sloan H, Guzzi M, Zhang X, Wang A, Rindgen D, Mazzola R, Vivian JA, Eddins D, Uslaner JM, Bednar R, Gambone C, Le-Mair W, Marino MJ, Sachs N, Xu G, Parmentier-Batteur S.
    Neuropharmacology; 2011 Sep; 61(4):665-76. PubMed ID: 21619887
    [Abstract] [Full Text] [Related]

  • 7. Repetitive induction of late-phase LTP produces long-lasting synaptic enhancement accompanied by synaptogenesis in cultured hippocampal slices.
    Tominaga-Yoshino K, Urakubo T, Okada M, Matsuda H, Ogura A.
    Hippocampus; 2008 Sep; 18(3):281-93. PubMed ID: 18058822
    [Abstract] [Full Text] [Related]

  • 8. Alterations in the balance of protein kinase and phosphatase activities and age-related impairments of synaptic transmission and long-term potentiation.
    Hsu KS, Huang CC, Liang YC, Wu HM, Chen YL, Lo SW, Ho WC.
    Hippocampus; 2002 Sep; 12(6):787-802. PubMed ID: 12542230
    [Abstract] [Full Text] [Related]

  • 9. Phosphodiesterase 4B (PDE4B) and cAMP-level regulation within different tissue fractions of rat hippocampal slices during long-term potentiation in vitro.
    Ahmed T, Frey JU.
    Brain Res; 2005 Apr 18; 1041(2):212-22. PubMed ID: 15829230
    [Abstract] [Full Text] [Related]

  • 10. Prolonged treatment with donepezil increases acetylcholinesterase expression in the central nervous system.
    Zivin M, Pregelj P.
    Psychiatr Danub; 2008 Jun 18; 20(2):168-73. PubMed ID: 18587286
    [Abstract] [Full Text] [Related]

  • 11. Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo.
    Kleiman RJ, Chapin DS, Christoffersen C, Freeman J, Fonseca KR, Geoghegan KF, Grimwood S, Guanowsky V, Hajós M, Harms JF, Helal CJ, Hoffmann WE, Kocan GP, Majchrzak MJ, McGinnis D, McLean S, Menniti FS, Nelson F, Roof R, Schmidt AW, Seymour PA, Stephenson DT, Tingley FD, Vanase-Frawley M, Verhoest PR, Schmidt CJ.
    J Pharmacol Exp Ther; 2012 May 18; 341(2):396-409. PubMed ID: 22328573
    [Abstract] [Full Text] [Related]

  • 12. The type IV-specific phosphodiesterase inhibitor rolipram and its effect on hippocampal long-term potentiation and synaptic tagging.
    Navakkode S, Sajikumar S, Frey JU.
    J Neurosci; 2004 Sep 01; 24(35):7740-4. PubMed ID: 15342741
    [Abstract] [Full Text] [Related]

  • 13. Plasticity-specific phosphorylation of CaMKII, MAP-kinases and CREB during late-LTP in rat hippocampal slices in vitro.
    Ahmed T, Frey JU.
    Neuropharmacology; 2005 Sep 01; 49(4):477-92. PubMed ID: 16005911
    [Abstract] [Full Text] [Related]

  • 14. Cholinergic modulation of hippocampal CA1 basal-dendritic long-term potentiation.
    Doralp S, Leung LS.
    Neurobiol Learn Mem; 2008 Sep 01; 90(2):382-8. PubMed ID: 18590828
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus.
    Fernández-Fernández D, Rosenbrock H, Kroker KS.
    Synapse; 2015 Oct 01; 69(10):484-96. PubMed ID: 26178667
    [Abstract] [Full Text] [Related]

  • 16. Protein kinase C mediates amyloid beta-protein fragment 31-35-induced suppression of hippocampal late-phase long-term potentiation in vivo.
    Zhang JF, Qi JS, Qiao JT.
    Neurobiol Learn Mem; 2009 Mar 01; 91(3):226-34. PubMed ID: 19061963
    [Abstract] [Full Text] [Related]

  • 17. Mitogen-activated protein kinase-mediated reinforcement of hippocampal early long-term depression by the type IV-specific phosphodiesterase inhibitor rolipram and its effect on synaptic tagging.
    Navakkode S, Sajikumar S, Frey JU.
    J Neurosci; 2005 Nov 16; 25(46):10664-70. PubMed ID: 16291939
    [Abstract] [Full Text] [Related]

  • 18. Augmentation of Endogenous Acetylcholine Uptake and Cholinergic Facilitation of Hippocampal Long-Term Potentiation by Acetylcholinesterase Inhibition.
    Masuoka T, Uwada J, Kudo M, Yoshiki H, Yamashita Y, Taniguchi T, Nishio M, Ishibashi T, Muramatsu I.
    Neuroscience; 2019 Apr 15; 404():39-47. PubMed ID: 30708046
    [Abstract] [Full Text] [Related]

  • 19. Sequential activation of soluble guanylate cyclase, protein kinase G and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in CA1 of hippocampus. Alterations in hyperammonemia.
    Monfort P, Muñoz MD, Kosenko E, Llansola M, Sánchez-Pérez A, Cauli O, Felipo V.
    Neurochem Int; 2004 Nov 15; 45(6):895-901. PubMed ID: 15312984
    [Abstract] [Full Text] [Related]

  • 20. Differential effects of subtype-specific nicotinic acetylcholine receptor agonists on early and late hippocampal LTP.
    Kroker KS, Rast G, Rosenbrock H.
    Eur J Pharmacol; 2011 Dec 05; 671(1-3):26-32. PubMed ID: 21968142
    [Abstract] [Full Text] [Related]

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