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1924 related items for PubMed ID: 22246241

  • 1. Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.
    Shin H, Kim JH, Lee YS, Lee YC.
    Int J Oncol; 2012 May; 40(5):1533-42. PubMed ID: 22246241
    [Abstract] [Full Text] [Related]

  • 2. Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.
    Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y.
    Oncogene; 2007 Jul 12; 26(32):4699-713. PubMed ID: 17297461
    [Abstract] [Full Text] [Related]

  • 3. Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.
    Cheng YY, Yu J, Wong YP, Man EP, To KF, Jin VX, Li J, Tao Q, Sung JJ, Chan FK, Leung WK.
    Br J Cancer; 2007 Oct 08; 97(7):895-901. PubMed ID: 17848950
    [Abstract] [Full Text] [Related]

  • 4. Hepatitis C virus core protein epigenetically silences SFRP1 and enhances HCC aggressiveness by inducing epithelial-mesenchymal transition.
    Quan H, Zhou F, Nie D, Chen Q, Cai X, Shan X, Zhou Z, Chen K, Huang A, Li S, Tang N.
    Oncogene; 2014 May 29; 33(22):2826-35. PubMed ID: 23770846
    [Abstract] [Full Text] [Related]

  • 5. Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.
    Urakami S, Shiina H, Enokida H, Kawakami T, Tokizane T, Ogishima T, Tanaka Y, Li LC, Ribeiro-Filho LA, Terashima M, Kikuno N, Adachi H, Yoneda T, Kishi H, Shigeno K, Konety BR, Igawa M, Dahiya R.
    Clin Cancer Res; 2006 Jan 15; 12(2):383-91. PubMed ID: 16428476
    [Abstract] [Full Text] [Related]

  • 6. Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.
    Lee SH, Kim J, Kim WH, Lee YM.
    Oncogene; 2009 Jan 15; 28(2):184-94. PubMed ID: 18850007
    [Abstract] [Full Text] [Related]

  • 7. SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.
    Chung MT, Lai HC, Sytwu HK, Yan MD, Shih YL, Chang CC, Yu MH, Liu HS, Chu DW, Lin YW.
    Gynecol Oncol; 2009 Mar 15; 112(3):646-53. PubMed ID: 19095296
    [Abstract] [Full Text] [Related]

  • 8. Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
    Chen W, Gao N, Shen Y, Cen JN.
    J Gastroenterol Hepatol; 2010 Apr 15; 25(4):823-31. PubMed ID: 20492341
    [Abstract] [Full Text] [Related]

  • 9. Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer.
    Aguilera O, Fraga MF, Ballestar E, Paz MF, Herranz M, Espada J, García JM, Muñoz A, Esteller M, González-Sancho JM.
    Oncogene; 2006 Jul 06; 25(29):4116-21. PubMed ID: 16491118
    [Abstract] [Full Text] [Related]

  • 10. Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma.
    Shih YL, Shyu RY, Hsieh CB, Lai HC, Liu KY, Chu TY, Lin YW.
    Cancer; 2006 Aug 01; 107(3):579-90. PubMed ID: 16795071
    [Abstract] [Full Text] [Related]

  • 11. Epigenetic inactivation of the canonical Wnt antagonist secreted frizzled-related protein 1 in hepatocellular carcinoma cells.
    Wu Y, Li J, Sun CY, Zhou Y, Zhao YF, Zhang SJ.
    Neoplasma; 2012 Aug 01; 59(3):326-32. PubMed ID: 22296502
    [Abstract] [Full Text] [Related]

  • 12. Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway.
    Xie Q, Chen L, Shan X, Shan X, Tang J, Zhou F, Chen Q, Quan H, Nie D, Zhang W, Huang AL, Tang N.
    Int J Cancer; 2014 Aug 01; 135(3):635-46. PubMed ID: 24374650
    [Abstract] [Full Text] [Related]

  • 13. [Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor].
    Qi J, Zhu YQ, Luo J, Tao WH, Zhang JM.
    Zhonghua Zhong Liu Za Zhi; 2007 Nov 01; 29(11):842-5. PubMed ID: 18396643
    [Abstract] [Full Text] [Related]

  • 14. Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo.
    Ramachandran I, Thavathiru E, Ramalingam S, Natarajan G, Mills WK, Benbrook DM, Zuna R, Lightfoot S, Reis A, Anant S, Queimado L.
    Oncogene; 2012 May 31; 31(22):2725-37. PubMed ID: 22002305
    [Abstract] [Full Text] [Related]

  • 15. Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.
    Taniguchi H, Yamamoto H, Hirata T, Miyamoto N, Oki M, Nosho K, Adachi Y, Endo T, Imai K, Shinomura Y.
    Oncogene; 2005 Nov 24; 24(53):7946-52. PubMed ID: 16007117
    [Abstract] [Full Text] [Related]

  • 16. Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.
    Clément G, Braunschweig R, Pasquier N, Bosman FT, Benhattar J.
    Oncogene; 2006 May 18; 25(21):3084-92. PubMed ID: 16407829
    [Abstract] [Full Text] [Related]

  • 17. Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma.
    Chim CS, Pang R, Fung TK, Choi CL, Liang R.
    Leukemia; 2007 Dec 18; 21(12):2527-36. PubMed ID: 17882284
    [Abstract] [Full Text] [Related]

  • 18. Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion.
    Kim M, Lee KT, Jang HR, Kim JH, Noh SM, Song KS, Cho JS, Jeong HY, Kim SY, Yoo HS, Kim YS.
    Mol Cancer Res; 2008 Feb 18; 6(2):222-30. PubMed ID: 18314483
    [Abstract] [Full Text] [Related]

  • 19. The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis.
    Dees C, Schlottmann I, Funke R, Distler A, Palumbo-Zerr K, Zerr P, Lin NY, Beyer C, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun 18; 73(6):1232-9. PubMed ID: 23698475
    [Abstract] [Full Text] [Related]

  • 20. Epigenetic demethylation of sFRPs, with emphasis on sFRP4 activation, leading to Wnt signalling suppression and histone modifications in breast, prostate, and ovary cancer stem cells.
    Deshmukh A, Arfuso F, Newsholme P, Dharmarajan A.
    Int J Biochem Cell Biol; 2019 Apr 18; 109():23-32. PubMed ID: 30710752
    [Abstract] [Full Text] [Related]

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