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107 related items for PubMed ID: 22248271

  • 1. Effects of pantoprazole as a HIF-1α inhibitor on human gastric adenocarcinoma sgc-7901 cells.
    Shen Y, Wu Y, Chen M, Shen W, Huang S, Zhang L, Zou X.
    Neoplasma; 2012; 59(2):142-9. PubMed ID: 22248271
    [Abstract] [Full Text] [Related]

  • 2. Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo.
    Chen M, Huang SL, Zhang XQ, Zhang B, Zhu H, Yang VW, Zou XP.
    J Cell Biochem; 2012 Jul; 113(7):2474-87. PubMed ID: 22396185
    [Abstract] [Full Text] [Related]

  • 3. Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer.
    Sun XP, Dong X, Lin L, Jiang X, Wei Z, Zhai B, Sun B, Zhang Q, Wang X, Jiang H, Krissansen GW, Qiao H, Sun X.
    FEBS J; 2014 Jan; 281(1):115-28. PubMed ID: 24165223
    [Abstract] [Full Text] [Related]

  • 4. Effect of pantoprazole on human gastric adenocarcinoma SGC7901 cells through regulation of phospho‑LRP6 expression in Wnt/β-catenin signaling.
    Shen W, Zou X, Chen M, Shen Y, Huang S, Guo H, Zhang L, Liu P.
    Oncol Rep; 2013 Aug; 30(2):851-5. PubMed ID: 23754096
    [Abstract] [Full Text] [Related]

  • 5. Selective induction of apoptosis with proton pump inhibitor in gastric cancer cells.
    Yeo M, Kim DK, Kim YB, Oh TY, Lee JE, Cho SW, Kim HC, Hahm KB.
    Clin Cancer Res; 2004 Dec 15; 10(24):8687-96. PubMed ID: 15623654
    [Abstract] [Full Text] [Related]

  • 6. HIF-1α is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer.
    Miyake S, Kitajima Y, Nakamura J, Kai K, Yanagihara K, Tanaka T, Hiraki M, Miyazaki K, Noshiro H.
    Int J Oncol; 2013 Nov 15; 43(5):1431-40. PubMed ID: 23970191
    [Abstract] [Full Text] [Related]

  • 7. Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.
    Lang SA, Gaumann A, Koehl GE, Seidel U, Bataille F, Klein D, Ellis LM, Bolder U, Hofstaedter F, Schlitt HJ, Geissler EK, Stoeltzing O.
    Int J Cancer; 2007 Apr 15; 120(8):1803-10. PubMed ID: 17230506
    [Abstract] [Full Text] [Related]

  • 8. Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial-mesenchymal transition.
    Zhang B, Yang Y, Shi X, Liao W, Chen M, Cheng AS, Yan H, Fang C, Zhang S, Xu G, Shen S, Huang S, Chen G, Lv Y, Ling T, Zhang X, Wang L, Zhuge Y, Zou X.
    Cancer Lett; 2015 Jan 28; 356(2 Pt B):704-12. PubMed ID: 25449432
    [Abstract] [Full Text] [Related]

  • 9. HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy.
    Nakamura J, Kitajima Y, Kai K, Hashiguchi K, Hiraki M, Noshiro H, Miyazaki K.
    Int J Cancer; 2010 Sep 01; 127(5):1158-71. PubMed ID: 20020496
    [Abstract] [Full Text] [Related]

  • 10. Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma.
    Kobayashi I, Semba S, Matsuda Y, Kuroda Y, Yokozaki H.
    Pathobiology; 2006 Sep 01; 73(1):8-17. PubMed ID: 16785763
    [Abstract] [Full Text] [Related]

  • 11. A possible involvement of Nrf2-mediated heme oxygenase-1 up-regulation in protective effect of the proton pump inhibitor pantoprazole against indomethacin-induced gastric damage in rats.
    Lee HJ, Han YM, Kim EH, Kim YJ, Hahm KB.
    BMC Gastroenterol; 2012 Oct 16; 12():143. PubMed ID: 23066659
    [Abstract] [Full Text] [Related]

  • 12. [Effect of RNA interference targeting HIF-1α gene on biological behavior of human esophageal squamous cell carcinoma and gastric adenocarcinoma cells in vitro].
    Zeng KF, Jin HL, Zhang WF, Xiao B, Zhu H, Hao B, Shi RH.
    Zhonghua Zhong Liu Za Zhi; 2011 Apr 16; 33(4):260-4. PubMed ID: 21575495
    [Abstract] [Full Text] [Related]

  • 13. HIF-1α siRNA and cisplatin in combination suppress tumor growth in a nude mice model of esophageal squamous cell carcinoma.
    Liao HY, Wang GP, Gu LJ, Huang SH, Chen XL, Li Y, Cai SW.
    Asian Pac J Cancer Prev; 2012 Apr 16; 13(2):473-7. PubMed ID: 22524809
    [Abstract] [Full Text] [Related]

  • 14. Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways.
    Wang JY, Wang Z, Li MY, Zhang Z, Mi C, Zuo HX, Xing Y, Wu YL, Lian LH, Xu GH, Piao LX, Ma J, Jin X.
    Chem Biol Interact; 2018 Dec 25; 296():134-144. PubMed ID: 30266538
    [Abstract] [Full Text] [Related]

  • 15. The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions.
    Tanaka T, Kitajima Y, Miyake S, Yanagihara K, Hara H, Nishijima-Matsunobu A, Baba K, Shida M, Wakiyama K, Nakamura J, Noshiro H.
    PLoS One; 2015 Dec 25; 10(9):e0137257. PubMed ID: 26339797
    [Abstract] [Full Text] [Related]

  • 16. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway.
    Wang H, Zhao L, Zhu LT, Wang Y, Pan D, Yao J, You QD, Guo QL.
    Mol Carcinog; 2014 Feb 25; 53 Suppl 1():E107-18. PubMed ID: 23761018
    [Abstract] [Full Text] [Related]

  • 17. Pharmacologic ascorbate (P-AscH-) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma.
    Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ.
    Clin Exp Metastasis; 2018 Feb 25; 35(1-2):37-51. PubMed ID: 29396728
    [Abstract] [Full Text] [Related]

  • 18. Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response.
    Guo D, Wang C, Wang Q, Qiao Z, Tang H.
    Oncotarget; 2017 Jun 13; 8(24):39640-39648. PubMed ID: 28489606
    [Abstract] [Full Text] [Related]

  • 19. MiR-338-3p inhibits hepatocarcinoma cells and sensitizes these cells to sorafenib by targeting hypoxia-induced factor 1α.
    Xu H, Zhao L, Fang Q, Sun J, Zhang S, Zhan C, Liu S, Zhang Y.
    PLoS One; 2014 Jun 13; 9(12):e115565. PubMed ID: 25531114
    [Abstract] [Full Text] [Related]

  • 20. Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinoma.
    Ezzeddini R, Taghikhani M, Somi MH, Samadi N, Rasaee MJ.
    Life Sci; 2019 May 01; 224():169-176. PubMed ID: 30914315
    [Abstract] [Full Text] [Related]

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