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Journal Abstract Search

186 related items for PubMed ID: 2224866

  • 1. Pharmacokinetic analysis of immunotoxin uptake in solid tumors: role of plasma kinetics, capillary permeability, and binding.
    Sung C, Youle RJ, Dedrick RL.
    Cancer Res; 1990 Nov 15; 50(22):7382-92. PubMed ID: 2224866
    [Abstract] [Full Text] [Related]

  • 2. The spatial distribution of immunotoxins in solid tumors: assessment by quantitative autoradiography.
    Sung C, Dedrick RL, Hall WA, Johnson PA, Youle RJ.
    Cancer Res; 1993 May 01; 53(9):2092-9. PubMed ID: 8481911
    [Abstract] [Full Text] [Related]

  • 3. A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels.
    Shockley TR, Lin K, Sung C, Nagy JA, Tompkins RG, Dedrick RL, Dvorak HF, Yarmush ML.
    Cancer Res; 1992 Jan 15; 52(2):357-66. PubMed ID: 1728407
    [Abstract] [Full Text] [Related]

  • 4. Coupled cellular trafficking and diffusional limitations in delivery of immunotoxins to multicell tumor spheroids.
    Wenning LA, Murphy RM.
    Biotechnol Bioeng; 1999 Mar 05; 62(5):562-75. PubMed ID: 10099565
    [Abstract] [Full Text] [Related]

  • 5. Predicted and observed effects of antibody affinity and antigen density on monoclonal antibody uptake in solid tumors.
    Sung C, Shockley TR, Morrison PF, Dvorak HF, Yarmush ML, Dedrick RL.
    Cancer Res; 1992 Jan 15; 52(2):377-84. PubMed ID: 1728409
    [Abstract] [Full Text] [Related]

  • 6. Recombinant immunotoxins directed against the c-erb-2/HER2/neu oncogene product: in vitro cytotoxicity, pharmacokinetics, and in vivo efficacy studies in xenograft models.
    Rosenblum MG, Shawver LK, Marks JW, Brink J, Cheung L, Langton-Webster B.
    Clin Cancer Res; 1999 Apr 15; 5(4):865-74. PubMed ID: 10213223
    [Abstract] [Full Text] [Related]

  • 7. Cytotoxicity against human tumor cells mediated by the conjugate of anti-epidermal growth factor receptor monoclonal antibody to recombinant ricin A chain.
    Masui H, Kamrath H, Apell G, Houston LL, Mendelsohn J.
    Cancer Res; 1989 Jul 01; 49(13):3482-8. PubMed ID: 2786451
    [Abstract] [Full Text] [Related]

  • 8. Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: permeability and receptor dependence.
    Aloj L, Jogoda E, Lang L, Caracò C, Neumann RD, Sung C, Eckelman WC.
    J Nucl Med; 1999 Sep 01; 40(9):1547-55. PubMed ID: 10492378
    [Abstract] [Full Text] [Related]

  • 9. An immunotoxin composed of a monoclonal antitransferrin receptor antibody linked by a disulfide bond to the ribosome-inactivating protein gelonin: potent in vitro and in vivo effects against human tumors.
    Scott CF, Goldmacher VS, Lambert JM, Jackson JV, McIntyre GD.
    J Natl Cancer Inst; 1987 Nov 01; 79(5):1163-72. PubMed ID: 3500356
    [Abstract] [Full Text] [Related]

  • 10. Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice.
    Baxter LT, Zhu H, Mackensen DG, Jain RK.
    Cancer Res; 1994 Mar 15; 54(6):1517-28. PubMed ID: 8137258
    [Abstract] [Full Text] [Related]

  • 11. Comparison of the pharmacokinetics and hepatotoxic effects of saporin and ricin A-chain immunotoxins on murine liver parenchymal cells.
    Blakey DC, Skilleter DN, Price RJ, Watson GJ, Hart LI, Newell DR, Thorpe PE.
    Cancer Res; 1988 Dec 15; 48(24 Pt 1):7072-8. PubMed ID: 3263899
    [Abstract] [Full Text] [Related]

  • 12. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.
    Jain RK, Baxter LT.
    Cancer Res; 1988 Dec 15; 48(24 Pt 1):7022-32. PubMed ID: 3191477
    [Abstract] [Full Text] [Related]

  • 13. Tumor-secreted vascular permeability factor/vascular endothelial growth factor influences photosensitizer uptake.
    Roberts WG, Hasan T.
    Cancer Res; 1993 Jan 01; 53(1):153-7. PubMed ID: 8416739
    [Abstract] [Full Text] [Related]

  • 14. Improved pharmacokinetics and tumor localization of immunotoxins constructed with the Mr 30,000 form of ricin A chain.
    Trown PW, Reardan DT, Carroll SF, Stoudemire JB, Kawahata RT.
    Cancer Res; 1991 Aug 15; 51(16):4219-25. PubMed ID: 1868442
    [Abstract] [Full Text] [Related]

  • 15. Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice.
    Spearman ME, Goodwin RM, Apelgren LD, Bumol TF.
    J Pharmacol Exp Ther; 1987 May 15; 241(2):695-703. PubMed ID: 3494841
    [Abstract] [Full Text] [Related]

  • 16. Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel.
    Bradley MO, Webb NL, Anthony FH, Devanesan P, Witman PA, Hemamalini S, Chander MC, Baker SD, He L, Horwitz SB, Swindell CS.
    Clin Cancer Res; 2001 Oct 15; 7(10):3229-38. PubMed ID: 11595719
    [Abstract] [Full Text] [Related]

  • 17. Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model.
    Marecos E, Weissleder R, Bogdanov A.
    Bioconjug Chem; 1998 Oct 15; 9(2):184-91. PubMed ID: 9548533
    [Abstract] [Full Text] [Related]

  • 18. Diphtheria toxin effects on brain-tumor xenografts. Implications for protein-based brain-tumor chemotherapy.
    Wrobel CJ, Wright DC, Dedrick RL, Youle RJ.
    J Neurosurg; 1990 Jun 15; 72(6):946-50. PubMed ID: 2159988
    [Abstract] [Full Text] [Related]

  • 19. A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma.
    Vallera DA, Todhunter DA, Kuroki DW, Shu Y, Sicheneder A, Chen H.
    Clin Cancer Res; 2005 May 15; 11(10):3879-88. PubMed ID: 15897589
    [Abstract] [Full Text] [Related]

  • 20. A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity.
    Dell'Arciprete L, Colombatti M, Rappuoli R, Tridente G.
    J Immunol; 1988 Apr 01; 140(7):2466-71. PubMed ID: 2965187
    [Abstract] [Full Text] [Related]

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