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238 related items for PubMed ID: 22249359

  • 1. Further characterization of the prototypical nociceptin/orphanin FQ peptide receptor agonist Ro 64-6198 in rodent models of conflict anxiety and despair.
    Goeldner C, Spooren W, Wichmann J, Prinssen EP.
    Psychopharmacology (Berl); 2012 Jul; 222(2):203-14. PubMed ID: 22249359
    [Abstract] [Full Text] [Related]

  • 2. The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.
    Witkin JM, Statnick MA, Rorick-Kehn LM, Pintar JE, Ansonoff M, Chen Y, Tucker RC, Ciccocioppo R.
    Pharmacol Ther; 2014 Mar; 141(3):283-99. PubMed ID: 24189487
    [Abstract] [Full Text] [Related]

  • 3. A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.
    Jenck F, Wichmann J, Dautzenberg FM, Moreau JL, Ouagazzal AM, Martin JR, Lundstrom K, Cesura AM, Poli SM, Roever S, Kolczewski S, Adam G, Kilpatrick G.
    Proc Natl Acad Sci U S A; 2000 Apr 25; 97(9):4938-43. PubMed ID: 10758169
    [Abstract] [Full Text] [Related]

  • 4. The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys.
    Podlesnik CA, Ko MC, Winger G, Wichmann J, Prinssen EP, Woods JH.
    Psychopharmacology (Berl); 2011 Jan 25; 213(1):53-60. PubMed ID: 20852848
    [Abstract] [Full Text] [Related]

  • 5. Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands.
    Asth L, Ruzza C, Malfacini D, Medeiros I, Guerrini R, Zaveri NT, Gavioli EC, Calo' G.
    Neuropharmacology; 2016 Jun 25; 105():434-442. PubMed ID: 26867504
    [Abstract] [Full Text] [Related]

  • 6. The orphanin receptor agonist RO 64-6198 does not induce place conditioning in rats.
    Le Pen G, Wichmann J, Moreau JL, Jenck F.
    Neuroreport; 2002 Mar 25; 13(4):451-4. PubMed ID: 11930159
    [Abstract] [Full Text] [Related]

  • 7. Modulation of the NOP receptor signaling affects resilience to acute stress.
    Holanda VAD, Pacifico S, Azevedo Neto J, Finetti L, Lobão-Soares B, Calo G, Gavioli EC, Ruzza C.
    J Psychopharmacol; 2019 Dec 25; 33(12):1540-1549. PubMed ID: 31337258
    [Abstract] [Full Text] [Related]

  • 8. Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys.
    Ko MC, Woods JH, Fantegrossi WE, Galuska CM, Wichmann J, Prinssen EP.
    Neuropsychopharmacology; 2009 Aug 25; 34(9):2088-96. PubMed ID: 19279568
    [Abstract] [Full Text] [Related]

  • 9. Effects of Ro 64-6198 in nociceptin/orphanin FQ-sensitive isolated tissues.
    Rizzi D, Bigoni R, Rizzi A, Jenck F, Wichmann J, Guerrini R, Regoli D, Calo G.
    Naunyn Schmiedebergs Arch Pharmacol; 2001 May 25; 363(5):551-5. PubMed ID: 11383716
    [Abstract] [Full Text] [Related]

  • 10. Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent.
    Hirao A, Imai A, Sugie Y, Yamada Y, Hayashi S, Toide K.
    J Pharmacol Sci; 2008 Mar 25; 106(3):361-8. PubMed ID: 18319566
    [Abstract] [Full Text] [Related]

  • 11. The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
    Varty GB, Lu SX, Morgan CA, Cohen-Williams ME, Hodgson RA, Smith-Torhan A, Zhang H, Fawzi AB, Graziano MP, Ho GD, Matasi J, Tulshian D, Coffin VL, Carey GJ.
    J Pharmacol Exp Ther; 2008 Aug 25; 326(2):672-82. PubMed ID: 18492950
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  • 14. Blockade of NOP receptor modulates anxiety-related behaviors in mice exposed to inescapable stress.
    Silva AI, Holanda VAD, Azevedo Neto JG, Silva Junior ED, Soares-Rachetti VP, Calo G, Ruzza C, Gavioli EC.
    Psychopharmacology (Berl); 2020 Jun 25; 237(6):1633-1642. PubMed ID: 32095915
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological characterization of the nociceptin/orphanin FQ receptor on ethanol-mediated motivational effects in infant and adolescent rats.
    Miranda-Morales RS, Pautassi RM.
    Behav Brain Res; 2016 Feb 01; 298(Pt A):88-96. PubMed ID: 25907741
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  • 17. Pharmacological properties of a novel nociceptin/orphanin FQ receptor agonist, 2-(3,5-dimethylpiperazin-1-yl)-1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazole, with anxiolytic potential.
    Hirao A, Imai A, Sugie Y, Tamura T, Shimokawa H, Toide K.
    Eur J Pharmacol; 2008 Jan 28; 579(1-3):189-95. PubMed ID: 18001707
    [Abstract] [Full Text] [Related]

  • 18. A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory.
    Higgins GA, Kew JN, Richards JG, Takeshima H, Jenck F, Adam G, Wichmann J, Kemp JA, Grottick AJ.
    Eur J Neurosci; 2002 Mar 28; 15(5):911-22. PubMed ID: 11906533
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  • 20. Effects of nociceptin/orphanin FQ receptor (NOP) agonist, Ro64-6198, on reactivity to acute pain in mice: comparison to morphine.
    Reiss D, Wichmann J, Tekeshima H, Kieffer BL, Ouagazzal AM.
    Eur J Pharmacol; 2008 Jan 28; 579(1-3):141-8. PubMed ID: 18031727
    [Abstract] [Full Text] [Related]

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