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332 related items for PubMed ID: 22250084

  • 1. Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88.
    Kato K, Lillehoj EP, Park YS, Umehara T, Hoffman NE, Madesh M, Kim KC.
    J Immunol; 2012 Feb 15; 188(4):2014-22. PubMed ID: 22250084
    [Abstract] [Full Text] [Related]

  • 2. Pseudomonas aeruginosa stimulates tyrosine phosphorylation of and TLR5 association with the MUC1 cytoplasmic tail through EGFR activation.
    Kato K, Lillehoj EP, Kim KC.
    Inflamm Res; 2016 Mar 15; 65(3):225-33. PubMed ID: 26645913
    [Abstract] [Full Text] [Related]

  • 3. MUC1 regulates epithelial inflammation and apoptosis by PolyI:C through inhibition of Toll/IL-1 receptor-domain-containing adapter-inducing IFN-β (TRIF) recruitment to Toll-like receptor 3.
    Kato K, Lillehoj EP, Kim KC.
    Am J Respir Cell Mol Biol; 2014 Sep 15; 51(3):446-54. PubMed ID: 24693944
    [Abstract] [Full Text] [Related]

  • 4. Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5.
    Zhang Z, Louboutin JP, Weiner DJ, Goldberg JB, Wilson JM.
    Infect Immun; 2005 Nov 15; 73(11):7151-60. PubMed ID: 16239509
    [Abstract] [Full Text] [Related]

  • 5. Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice.
    Lu W, Hisatsune A, Koga T, Kato K, Kuwahara I, Lillehoj EP, Chen W, Cross AS, Gendler SJ, Gewirtz AT, Kim KC.
    J Immunol; 2006 Apr 01; 176(7):3890-4. PubMed ID: 16547220
    [Abstract] [Full Text] [Related]

  • 6. Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism.
    Anas AA, van Lieshout MH, Claushuis TA, de Vos AF, Florquin S, de Boer OJ, Hou B, Van't Veer C, van der Poll T.
    Am J Physiol Lung Cell Mol Physiol; 2016 Aug 01; 311(2):L219-28. PubMed ID: 27288486
    [Abstract] [Full Text] [Related]

  • 7. TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells.
    Choi YJ, Im E, Chung HK, Pothoulakis C, Rhee SH.
    J Biol Chem; 2010 Nov 26; 285(48):37570-8. PubMed ID: 20855887
    [Abstract] [Full Text] [Related]

  • 8. A crucial role of Flagellin in the induction of airway mucus production by Pseudomonas aeruginosa.
    Ben Mohamed F, Garcia-Verdugo I, Medina M, Balloy V, Chignard M, Ramphal R, Touqui L.
    PLoS One; 2012 Nov 26; 7(7):e39888. PubMed ID: 22768318
    [Abstract] [Full Text] [Related]

  • 9. Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5.
    Adamo R, Sokol S, Soong G, Gomez MI, Prince A.
    Am J Respir Cell Mol Biol; 2004 May 26; 30(5):627-34. PubMed ID: 14607814
    [Abstract] [Full Text] [Related]

  • 10. The p38 mitogen-activated protein kinase signaling pathway is coupled to Toll-like receptor 5 to mediate gene regulation in response to Pseudomonas aeruginosa infection in human airway epithelial cells.
    Zhang Z, Reenstra W, Weiner DJ, Louboutin JP, Wilson JM.
    Infect Immun; 2007 Dec 26; 75(12):5985-92. PubMed ID: 17908812
    [Abstract] [Full Text] [Related]

  • 11. Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-kappa B and proinflammatory gene program activation in intestinal epithelial cells.
    Tallant T, Deb A, Kar N, Lupica J, de Veer MJ, DiDonato JA.
    BMC Microbiol; 2004 Aug 23; 4():33. PubMed ID: 15324458
    [Abstract] [Full Text] [Related]

  • 12. Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells.
    Rhee SH, Kim H, Moyer MP, Pothoulakis C.
    J Biol Chem; 2006 Jul 07; 281(27):18560-8. PubMed ID: 16644730
    [Abstract] [Full Text] [Related]

  • 13. MUC1 attenuates neutrophilic airway inflammation in asthma by reducing NLRP3 inflammasome-mediated pyroptosis through the inhibition of the TLR4/MyD88/NF-κB pathway.
    Liu L, Zhou L, Wang L, Mao Z, Zheng P, Zhang F, Zhang H, Liu H.
    Respir Res; 2023 Oct 25; 24(1):255. PubMed ID: 37880668
    [Abstract] [Full Text] [Related]

  • 14. NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.
    Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE.
    J Biol Chem; 2012 Mar 09; 287(11):8214-31. PubMed ID: 22247545
    [Abstract] [Full Text] [Related]

  • 15. Pseudomonas aeruginosa stimulates phosphorylation of the airway epithelial membrane glycoprotein Muc1 and activates MAP kinase.
    Lillehoj EP, Kim H, Chun EY, Kim KC.
    Am J Physiol Lung Cell Mol Physiol; 2004 Oct 09; 287(4):L809-15. PubMed ID: 15220114
    [Abstract] [Full Text] [Related]

  • 16. The TLR2 ligand FSL-1 and the TLR5 ligand Flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-κB-dependent signalling.
    Lim R, Barker G, Lappas M.
    Am J Reprod Immunol; 2014 May 09; 71(5):401-17. PubMed ID: 24635133
    [Abstract] [Full Text] [Related]

  • 17. TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism.
    Yu Y, Zeng H, Lyons S, Carlson A, Merlin D, Neish AS, Gewirtz AT.
    Am J Physiol Gastrointest Liver Physiol; 2003 Aug 09; 285(2):G282-90. PubMed ID: 12702497
    [Abstract] [Full Text] [Related]

  • 18. PPARγ inhibits airway epithelial cell inflammatory response through a MUC1-dependent mechanism.
    Park YS, Lillehoj EP, Kato K, Park CS, Kim KC.
    Am J Physiol Lung Cell Mol Physiol; 2012 Apr 01; 302(7):L679-87. PubMed ID: 22268120
    [Abstract] [Full Text] [Related]

  • 19. Phosphoinositide 3-kinase is activated by MUC1 but not responsible for MUC1-induced suppression of Toll-like receptor 5 signaling.
    Kato K, Lu W, Kai H, Kim KC.
    Am J Physiol Lung Cell Mol Physiol; 2007 Sep 01; 293(3):L686-92. PubMed ID: 17586693
    [Abstract] [Full Text] [Related]

  • 20. Involvement of epidermal growth factor receptor-linked signaling responses in Pseudomonas fluorescens-infected alveolar epithelial cells.
    Choi HJ, Seo CH, Park SH, Yang H, Do KH, Kim J, Kim HK, Chung DH, Ahn JH, Moon Y.
    Infect Immun; 2011 May 01; 79(5):1998-2005. PubMed ID: 21343351
    [Abstract] [Full Text] [Related]

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