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Journal Abstract Search

253 related items for PubMed ID: 22258492

  • 1. Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis.
    Reich N, Tomcik M, Zerr P, Lang V, Dees C, Avouac J, Palumbo K, Horn A, Akhmetshina A, Beyer C, Xie W, Bennett BL, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2012 May; 71(5):737-45. PubMed ID: 22258492
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  • 3. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.
    Distler JH, Jüngel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, Michel BA, Hauser T, Schett G, Gay S, Distler O.
    Arthritis Rheum; 2007 Jan; 56(1):311-22. PubMed ID: 17195235
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  • 4. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J.
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
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  • 5. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 May; 74(5):936-43. PubMed ID: 24431397
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  • 6. JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.
    Dees C, Tomcik M, Palumbo-Zerr K, Distler A, Beyer C, Lang V, Horn A, Zerr P, Zwerina J, Gelse K, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2012 Sep; 64(9):3006-15. PubMed ID: 22549363
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  • 9. The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.
    Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2010 Jan; 62(1):280-90. PubMed ID: 20039427
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  • 10. The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis.
    Krönke G, Reich N, Scholtysek C, Akhmetshina A, Uderhardt S, Zerr P, Palumbo K, Lang V, Dees C, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2012 Jun; 71(6):1081-7. PubMed ID: 22267335
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  • 12. Poly(ADP-ribose) polymerase-1 regulates fibroblast activation in systemic sclerosis.
    Zhang Y, Pötter S, Chen CW, Liang R, Gelse K, Ludolph I, Horch RE, Distler O, Schett G, Distler JHW, Dees C.
    Ann Rheum Dis; 2018 May; 77(5):744-751. PubMed ID: 29431122
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  • 13. Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.
    Tomcik M, Zerr P, Pitkowski J, Palumbo-Zerr K, Avouac J, Distler O, Becvar R, Senolt L, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1215-22. PubMed ID: 23661493
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  • 14. Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis.
    Yoshizaki A, Yanaba K, Yoshizaki A, Iwata Y, Komura K, Ogawa F, Takenaka M, Shimizu K, Asano Y, Hasegawa M, Fujimoto M, Sato S.
    Arthritis Rheum; 2010 Aug; 62(8):2476-87. PubMed ID: 20506342
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  • 17. Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis.
    Akhmetshina A, Venalis P, Dees C, Busch N, Zwerina J, Schett G, Distler O, Distler JH.
    Arthritis Rheum; 2009 Jan; 60(1):219-24. PubMed ID: 19116940
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  • 19. Activation of pregnane X receptor inhibits experimental dermal fibrosis.
    Beyer C, Skapenko A, Distler A, Dees C, Reichert H, Munoz L, Leipe J, Schulze-Koops H, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2013 Apr; 72(4):621-5. PubMed ID: 23291432
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