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140 related items for PubMed ID: 22264868

  • 1. Characterization of the neuropsychological phenotype of glycine N-methyltransferase-/- mice and evaluation of its responses to clozapine and sarcosine treatments.
    Yang CP, Wang HA, Tsai TH, Fan A, Hsu CL, Chen CJ, Hong CJ, Chen YM.
    Eur Neuropsychopharmacol; 2012 Aug; 22(8):596-606. PubMed ID: 22264868
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  • 5. Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
    Huang Y, Komoto J, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F.
    J Mol Biol; 2000 Apr 21; 298(1):149-62. PubMed ID: 10756111
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  • 6. Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
    Wang YC, Tang FY, Chen SY, Chen YM, Chiang EP.
    J Nutr; 2011 May 21; 141(5):777-82. PubMed ID: 21411609
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  • 7. Glycine N-methyltransferase affects the metabolism of aflatoxin B1 and blocks its carcinogenic effect.
    Yen CH, Hung JH, Ueng YF, Liu SP, Chen SY, Liu HH, Chou TY, Tsai TF, Darbha R, Hsieh LL, Chen YM.
    Toxicol Appl Pharmacol; 2009 Mar 15; 235(3):296-304. PubMed ID: 19146867
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  • 8. Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia.
    Lane HY, Huang CL, Wu PL, Liu YC, Chang YC, Lin PY, Chen PW, Tsai G.
    Biol Psychiatry; 2006 Sep 15; 60(6):645-9. PubMed ID: 16780811
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  • 9. GNMT expression increases hepatic folate contents and folate-dependent methionine synthase-mediated homocysteine remethylation.
    Wang YC, Chen YM, Lin YJ, Liu SP, Chiang EP.
    Mol Med; 2011 Sep 15; 17(5-6):486-94. PubMed ID: 21210071
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  • 10. Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver.
    Liao YJ, Chen KH, Huang SF, Chen TL, Wang CK, Chien CH, Tsai TF, Liu SP, Chen YM.
    Proteomics Clin Appl; 2010 Apr 15; 4(4):394-406. PubMed ID: 21137059
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  • 11. Benzo[a]pyrene effects on glycine N-methyltransferase mRNA expression and enzyme activity in Fundulus heteroclitus embryos.
    Fang X, Dong W, Thornton C, Willett KL.
    Aquat Toxicol; 2010 Jun 10; 98(2):130-8. PubMed ID: 20185185
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  • 12. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.
    Liao YJ, Liu SP, Lee CM, Yen CH, Chuang PC, Chen CY, Tsai TF, Huang SF, Lee YH, Chen YM.
    Int J Cancer; 2009 Feb 15; 124(4):816-26. PubMed ID: 19035462
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  • 13. Role of glycine N-methyltransferase in experimental ulcerative colitis.
    Chou WY, Zhao JF, Chen YM, Lee KI, Su KH, Shyue SK, Lee TS.
    J Gastroenterol Hepatol; 2014 Mar 15; 29(3):494-501. PubMed ID: 24219143
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  • 14. Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes.
    Møller MT, Samari HR, Fengsrud M, Strømhaug PE, øStvold AC, Seglen PO.
    Biochem J; 2003 Jul 15; 373(Pt 2):505-13. PubMed ID: 12697024
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  • 15. Benzo(a)pyrene induced glycine N-methyltransferase messenger RNA expression in Fundulus heteroclitus embryos.
    Fang X, Dong W, Thornton C, Scheffler B, Willett KL.
    Mar Environ Res; 2010 Jul 15; 69 Suppl():S74-6. PubMed ID: 19892394
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  • 16. The effects of glycine transporter I inhibitor, N-methylglycine (sarcosine), on ketamine-induced alterations in sensorimotor gating and regional brain c-Fos expression in rats.
    Yang SY, Hong CJ, Huang YH, Tsai SJ.
    Neurosci Lett; 2010 Jan 18; 469(1):127-30. PubMed ID: 19944746
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  • 17. Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
    Martínez-Chantar ML, Vázquez-Chantada M, Ariz U, Martínez N, Varela M, Luka Z, Capdevila A, Rodríguez J, Aransay AM, Matthiesen R, Yang H, Calvisi DF, Esteller M, Fraga M, Lu SC, Wagner C, Mato JM.
    Hepatology; 2008 Apr 18; 47(4):1191-9. PubMed ID: 18318442
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  • 18. A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization.
    DebRoy S, Kramarenko II, Ghose S, Oleinik NV, Krupenko SA, Krupenko NI.
    PLoS One; 2013 Apr 18; 8(7):e70062. PubMed ID: 23936142
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  • 19. Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates.
    Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH.
    J Biol Chem; 2018 Jul 27; 293(30):11944-11954. PubMed ID: 29891549
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  • 20. Mutations in human glycine N-methyltransferase give insights into its role in methionine metabolism.
    Luka Z, Cerone R, Phillips JA, Mudd HS, Wagner C.
    Hum Genet; 2002 Jan 27; 110(1):68-74. PubMed ID: 11810299
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