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Journal Abstract Search

379 related items for PubMed ID: 22266842

  • 1. Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist.
    Usmani KA, Chen WG, Sadeque AJ.
    Drug Metab Dispos; 2012 Apr; 40(4):761-71. PubMed ID: 22266842
    [Abstract] [Full Text] [Related]

  • 2. Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin.
    Sadeque AJ, Usmani KA, Palamar S, Cerny MA, Chen WG.
    Drug Metab Dispos; 2012 Apr; 40(4):772-8. PubMed ID: 22259019
    [Abstract] [Full Text] [Related]

  • 3. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Gallagher EP, Wienkers LC, Stapleton PL, Kunze KL, Eaton DL.
    Cancer Res; 1994 Jan 01; 54(1):101-8. PubMed ID: 8261428
    [Abstract] [Full Text] [Related]

  • 4. Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation.
    Engel G, Hofmann U, Heidemann H, Cosme J, Eichelbaum M.
    Clin Pharmacol Ther; 1996 Jun 01; 59(6):613-23. PubMed ID: 8681486
    [Abstract] [Full Text] [Related]

  • 5. In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism.
    Yu J, Brown DG, Burdette D.
    Drug Metab Dispos; 2010 Oct 01; 38(10):1767-78. PubMed ID: 20595377
    [Abstract] [Full Text] [Related]

  • 6. Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes.
    Guo Z, Raeissi S, White RB, Stevens JC.
    Drug Metab Dispos; 1997 Mar 01; 25(3):390-3. PubMed ID: 9172960
    [Abstract] [Full Text] [Related]

  • 7. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
    Botsch S, Gautier JC, Beaune P, Eichelbaum M, Kroemer HK.
    Mol Pharmacol; 1993 Jan 01; 43(1):120-6. PubMed ID: 8423765
    [Abstract] [Full Text] [Related]

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  • 9. In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol.
    Usmani KA, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Dec 07; 150(3):221-32. PubMed ID: 15560889
    [Abstract] [Full Text] [Related]

  • 10. In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450.
    Koga N, Ohta C, Kato Y, Haraguchi K, Endo T, Ogawa K, Ohta H, Yano M.
    Xenobiotica; 2011 Nov 07; 41(11):927-33. PubMed ID: 21726170
    [Abstract] [Full Text] [Related]

  • 11. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C, Benyamina A, Llorca PM, Baylé F, Bromet N, Massiere F, Garay RP, Hameg A.
    Eur J Pharm Sci; 2007 Dec 07; 32(4-5):357-66. PubMed ID: 17951033
    [Abstract] [Full Text] [Related]

  • 12. Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.
    Parte P, Kupfer D.
    Drug Metab Dispos; 2005 Oct 07; 33(10):1446-52. PubMed ID: 15987777
    [Abstract] [Full Text] [Related]

  • 13. In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine.
    Luo JP, Vashishtha SC, Hawes EM, McKay G, Midha KK, Fang J.
    Biopharm Drug Dispos; 2011 Oct 07; 32(7):398-407. PubMed ID: 21826677
    [Abstract] [Full Text] [Related]

  • 14. In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
    Fang J, McKay G, Song J, Remillrd A, Li X, Midha K.
    Drug Metab Dispos; 2001 Dec 07; 29(12):1638-43. PubMed ID: 11717183
    [Abstract] [Full Text] [Related]

  • 15. Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine.
    Fang J, Coutts RT, McKenna KF, Baker GB.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Nov 07; 358(5):592-9. PubMed ID: 9840430
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
    Bakken GV, Molden E, Knutsen K, Lunder N, Hermann M.
    Drug Metab Dispos; 2012 Sep 07; 40(9):1778-84. PubMed ID: 22688609
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028.
    Kim H, Yoon YJ, Kim H, Kang S, Cheon HG, Yoo SE, Shin JG, Liu KH.
    Toxicol Lett; 2006 Oct 10; 166(2):105-14. PubMed ID: 16857327
    [Abstract] [Full Text] [Related]

  • 18. Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
    Filppula AM, Laitila J, Neuvonen PJ, Backman JT.
    Drug Metab Dispos; 2011 May 10; 39(5):904-11. PubMed ID: 21289076
    [Abstract] [Full Text] [Related]

  • 19. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4--implications for susceptibility to Parkinson's disease.
    Coleman T, Ellis SW, Martin IJ, Lennard MS, Tucker GT.
    J Pharmacol Exp Ther; 1996 May 10; 277(2):685-90. PubMed ID: 8627546
    [Abstract] [Full Text] [Related]

  • 20. Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N.
    Biochem Pharmacol; 2006 Apr 28; 71(9):1377-85. PubMed ID: 16510126
    [Abstract] [Full Text] [Related]

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