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Journal Abstract Search

181 related items for PubMed ID: 22267166

  • 21. A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site.
    Mamais M, Degli Esposti A, Kouloumoundra V, Gustavsson T, Monti F, Venturini A, Chrysina ED, Markovitsi D, Gimisis T.
    Chemistry; 2017 Jul 03; 23(37):8800-8805. PubMed ID: 28493496
    [Abstract] [Full Text] [Related]

  • 22. The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: synthesis, biochemical and biological assessment.
    Kantsadi AL, Manta S, Psarra AM, Dimopoulou A, Kiritsis C, Parmenopoulou V, Skamnaki VT, Zoumpoulakis P, Zographos SE, Leonidas DD, Komiotis D.
    Eur J Med Chem; 2012 Aug 03; 54():740-9. PubMed ID: 22770609
    [Abstract] [Full Text] [Related]

  • 23. Halogen bonding--a novel interaction for rational drug design?
    Lu Y, Shi T, Wang Y, Yang H, Yan X, Luo X, Jiang H, Zhu W.
    J Med Chem; 2009 May 14; 52(9):2854-62. PubMed ID: 19358610
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  • 24. The role of molecular electrostatic potentials in the formation of a halogen bond in furan⋅⋅⋅XY and thiophene⋅⋅⋅XY complexes.
    Zeng Y, Zhang X, Li X, Meng L, Zheng S.
    Chemphyschem; 2011 Apr 18; 12(6):1080-7. PubMed ID: 21432980
    [Abstract] [Full Text] [Related]

  • 25. Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase.
    Anagnostou E, Kosmopoulou MN, Chrysina ED, Leonidas DD, Hadjiloi T, Tiraidis C, Zographos SE, Györgydeák Z, Somsák L, Docsa T, Gergely P, Kolisis FN, Oikonomakos NG.
    Bioorg Med Chem; 2006 Jan 01; 14(1):181-9. PubMed ID: 16213146
    [Abstract] [Full Text] [Related]

  • 26. Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors.
    Chetter BA, Kyriakis E, Barr D, Karra AG, Katsidou E, Koulas SM, Skamnaki VT, Snape TJ, Psarra AG, Leonidas DD, Hayes JM.
    Bioorg Chem; 2020 Sep 01; 102():104003. PubMed ID: 32771768
    [Abstract] [Full Text] [Related]

  • 27. Synthesis, screening and docking of small heterocycles as glycogen phosphorylase inhibitors.
    Schweiker SS, Loughlin WA, Lohning AS, Petersson MJ, Jenkins ID.
    Eur J Med Chem; 2014 Sep 12; 84():584-94. PubMed ID: 25062009
    [Abstract] [Full Text] [Related]

  • 28. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
    Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L.
    J Med Chem; 2006 Sep 21; 49(19):5687-701. PubMed ID: 16970395
    [Abstract] [Full Text] [Related]

  • 29. Synthesis of substituted 2-(β-D-glucopyranosyl)-benzimidazoles and their evaluation as inhibitors of glycogen phosphorylase.
    Bokor É, Szilágyi E, Docsa T, Gergely P, Somsák L.
    Carbohydr Res; 2013 Nov 15; 381():179-86. PubMed ID: 23419607
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  • 30. Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads.
    Habash M, Taha MO.
    Bioorg Med Chem; 2011 Aug 15; 19(16):4746-71. PubMed ID: 21788139
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  • 31. Synthesis of N-glucopyranosidic derivatives as potential inhibitors that bind at the catalytic site of glycogen phosphorylase.
    Gimisis T.
    Mini Rev Med Chem; 2010 Oct 15; 10(12):1127-38. PubMed ID: 20716054
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  • 32. Halogen bonding in ligand-receptor systems in the framework of classical force fields.
    Rendine S, Pieraccini S, Forni A, Sironi M.
    Phys Chem Chem Phys; 2011 Nov 21; 13(43):19508-16. PubMed ID: 21964576
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  • 33. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG, Somsák L.
    Curr Opin Investig Drugs; 2008 Apr 21; 9(4):379-95. PubMed ID: 18393105
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  • 34. Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies.
    Chrysina ED, Kosmopoulou MN, Kardakaris R, Bischler N, Leonidas DD, Kannan T, Loganathan D, Oikonomakos NG.
    Bioorg Med Chem; 2005 Feb 01; 13(3):765-72. PubMed ID: 15653344
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  • 35. Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N´-(β-D-glucopyranosyl) urea inhibitors.
    Kantsadi AL, Parmenopoulou V, Bakalov DN, Snelgrove L, Stravodimos GA, Chatzileontiadou DS, Manta S, Panagiotopoulou A, Hayes JM, Komiotis D, Leonidas DD.
    Curr Top Med Chem; 2015 Feb 01; 15(23):2373-89. PubMed ID: 26088352
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  • 36. Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines.
    Parmenopoulou V, Kantsadi AL, Tsirkone VG, Chatzileontiadou DS, Manta S, Zographos SE, Molfeta C, Archontis G, Agius L, Hayes JM, Leonidas DD, Komiotis D.
    Bioorg Med Chem; 2014 Sep 01; 22(17):4810-25. PubMed ID: 25092521
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  • 37. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M, Andersen B, Iversen LF, Westergaard N.
    J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781
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  • 38. Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.
    Watson KA, Mitchell EP, Johnson LN, Cruciani G, Son JC, Bichard CJ, Fleet GW, Oikonomakos NG, Kontou M, Zographos SE.
    Acta Crystallogr D Biol Crystallogr; 1995 Jul 01; 51(Pt 4):458-72. PubMed ID: 15299833
    [Abstract] [Full Text] [Related]

  • 39. Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
    Mitchell EP, Withers SG, Ermert P, Vasella AT, Garman EF, Oikonomakos NG, Johnson LN.
    Biochemistry; 1996 Jun 11; 35(23):7341-55. PubMed ID: 8652510
    [Abstract] [Full Text] [Related]

  • 40. Synthesis, In Silico and Kinetics Evaluation of N-(β-d-glucopyranosyl)-2-arylimidazole-4(5)-carboxamides and N-(β-d-glucopyranosyl)-4(5)-arylimidazole-2-carboxamides as Glycogen Phosphorylase Inhibitors.
    Homolya L, Mathomes RT, Varga L, Docsa T, Juhász L, Hayes JM, Somsák L.
    Int J Mol Sci; 2024 Apr 23; 25(9):. PubMed ID: 38731811
    [Abstract] [Full Text] [Related]

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