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PUBMED FOR HANDHELDS

Journal Abstract Search


225 related items for PubMed ID: 22278975

  • 1. Diarylheterocycle core ring features effect in selective COX-1 inhibition.
    Perrone MG, Vitale P, Malerba P, Altomare A, Rizzi R, Lavecchia A, Di Giovanni C, Novellino E, Scilimati A.
    ChemMedChem; 2012 Apr; 7(4):629-41. PubMed ID: 22278975
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  • 5. Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6).
    Cingolani G, Panella A, Perrone MG, Vitale P, Di Mauro G, Fortuna CG, Armen RS, Ferorelli S, Smith WL, Scilimati A.
    Eur J Med Chem; 2017 Sep 29; 138():661-668. PubMed ID: 28710965
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  • 7. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
    Praveen Rao PN, Amini M, Li H, Habeeb AG, Knaus EE.
    J Med Chem; 2003 Nov 06; 46(23):4872-82. PubMed ID: 14584938
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  • 8. Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs).
    Perrone MG, Vitale P, Panella A, Ferorelli S, Contino M, Lavecchia A, Scilimati A.
    ChemMedChem; 2016 Jun 06; 11(11):1172-87. PubMed ID: 27136372
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  • 9. Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors.
    Zarghi A, Zebardast T, Hakimion F, Shirazi FH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2006 Oct 15; 14(20):7044-50. PubMed ID: 16798002
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  • 11. Trimethyl-4-oxo-4,5,6,7-tetrahydroindazole-1-acetic acid: a new lead compound with selective COX-2 inhibitory activity.
    Abdel-Rahman HM, Ozadali K.
    Arch Pharm (Weinheim); 2012 Nov 15; 345(11):878-83. PubMed ID: 22907715
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  • 15. Design of novel N-phenylnicotinamides as selective cyclooxygenase-1 inhibitors.
    Shi L, Li ZL, Yang Y, Zhu ZW, Zhu HL.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):121-4. PubMed ID: 21144750
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  • 16. Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal.
    Di Nunno L, Vitale P, Scilimati A, Tacconelli S, Patrignani P.
    J Med Chem; 2004 Sep 23; 47(20):4881-90. PubMed ID: 15369392
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  • 17. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2005 Dec 01; 13(23):6425-34. PubMed ID: 16099663
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  • 18. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
    Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):437-42. PubMed ID: 16290146
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  • 19. Cyclooxygenase-1 and cyclooxygenase-2 inhibition of novel 1,2-disubstituted imidazoles.
    Handler N, Jaeger W, Kuen-Krismer B, Erker T.
    Arch Pharm (Weinheim); 2005 Dec 15; 338(12):602-4. PubMed ID: 16353278
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  • 20. Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors.
    Zanatta SD, Manallack DT, Jarrott B, Williams SJ.
    Bioorg Med Chem Lett; 2009 Jan 15; 19(2):459-61. PubMed ID: 19056264
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