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Journal Abstract Search

291 related items for PubMed ID: 22280146

  • 1. A hexane fraction of guava Leaves (Psidium guajava L.) induces anticancer activity by suppressing AKT/mammalian target of rapamycin/ribosomal p70 S6 kinase in human prostate cancer cells.
    Ryu NH, Park KR, Kim SM, Yun HM, Nam D, Lee SG, Jang HJ, Ahn KS, Kim SH, Shim BS, Choi SH, Mosaddik A, Cho SK, Ahn KS.
    J Med Food; 2012 Mar; 15(3):231-41. PubMed ID: 22280146
    [Abstract] [Full Text] [Related]

  • 2. β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation.
    Park KR, Nam D, Yun HM, Lee SG, Jang HJ, Sethi G, Cho SK, Ahn KS.
    Cancer Lett; 2011 Dec 22; 312(2):178-88. PubMed ID: 21924548
    [Abstract] [Full Text] [Related]

  • 3. Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.
    Kim SW, Kim SM, Bae H, Nam D, Lee JH, Lee SG, Shim BS, Kim SH, Ahn KS, Choi SH, Sethi G, Ahn KS.
    Prostate; 2013 Feb 15; 73(3):296-305. PubMed ID: 22887478
    [Abstract] [Full Text] [Related]

  • 4. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.
    Kim SM, Park JH, Kim KD, Nam D, Shim BS, Kim SH, Ahn KS, Choi SH, Ahn KS.
    Phytother Res; 2014 Mar 15; 28(3):423-31. PubMed ID: 23686889
    [Abstract] [Full Text] [Related]

  • 5. The mammalian target of rapamycin-p70 ribosomal S6 kinase but not phosphatidylinositol 3-kinase-Akt signaling is responsible for fibroblast growth factor-9-induced cell proliferation.
    Wing LY, Chen HM, Chuang PC, Wu MH, Tsai SJ.
    J Biol Chem; 2005 May 20; 280(20):19937-47. PubMed ID: 15760907
    [Abstract] [Full Text] [Related]

  • 6. Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.
    Wu JC, Lai CS, Badmaev V, Nagabhushanam K, Ho CT, Pan MH.
    Mol Nutr Food Res; 2011 Nov 20; 55(11):1646-54. PubMed ID: 21928294
    [Abstract] [Full Text] [Related]

  • 7. Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells.
    Zhao G, Han X, Zheng S, Li Z, Sha Y, Ni J, Sun Z, Qiao S, Song Z.
    Oncol Rep; 2016 Feb 20; 35(2):1065-74. PubMed ID: 26573768
    [Abstract] [Full Text] [Related]

  • 8. Quercetin-6-C-β-D-glucopyranoside, natural analog of quercetin exhibits anti-prostate cancer activity by inhibiting Akt-mTOR pathway via aryl hydrocarbon receptor.
    Hamidullah, Kumar R, Saini KS, Kumar A, Kumar S, Ramakrishna E, Maurya R, Konwar R, Chattopadhyay N.
    Biochimie; 2015 Dec 20; 119():68-79. PubMed ID: 26476001
    [Abstract] [Full Text] [Related]

  • 9. A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells.
    Morad SA, Schmid M, Büchele B, Siehl HU, El Gafaary M, Lunov O, Syrovets T, Simmet T.
    Mol Pharmacol; 2013 Feb 20; 83(2):531-41. PubMed ID: 23208958
    [Abstract] [Full Text] [Related]

  • 10. Vascular tumors have increased p70 S6-kinase activation and are inhibited by topical rapamycin.
    Du W, Gerald D, Perruzzi CA, Rodriguez-Waitkus P, Enayati L, Krishnan B, Edmonds J, Hochman ML, Lev DC, Phung TL.
    Lab Invest; 2013 Oct 20; 93(10):1115-27. PubMed ID: 23938603
    [Abstract] [Full Text] [Related]

  • 11. Fenofibrate inhibits mTOR-p70S6K signaling and simultaneously induces cell death in human prostate cancer cells.
    Lian X, Gu J, Gao B, Li Y, Damodaran C, Wei W, Fu Y, Cai L.
    Biochem Biophys Res Commun; 2018 Jan 29; 496(1):70-75. PubMed ID: 29305864
    [Abstract] [Full Text] [Related]

  • 12. Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
    Ghosh PM, Malik SN, Bedolla RG, Wang Y, Mikhailova M, Prihoda TJ, Troyer DA, Kreisberg JI.
    Endocr Relat Cancer; 2005 Mar 29; 12(1):119-34. PubMed ID: 15788644
    [Abstract] [Full Text] [Related]

  • 13. Action mechanism and signal pathways of Psidium guajava L. aqueous extract in killing prostate cancer LNCaP cells.
    Chen KC, Peng CC, Chiu WT, Cheng YT, Huang GT, Hsieh CL, Peng RY.
    Nutr Cancer; 2010 Mar 29; 62(2):260-70. PubMed ID: 20099201
    [Abstract] [Full Text] [Related]

  • 14. Silencing the FOLR2 Gene Inhibits Cell Proliferation and Increases Apoptosis in the NCI-H1650 Non-Small Cell Lung Cancer Cell Line via Inhibition of AKT/Mammalian Target of Rapamycin (mTOR)/Ribosomal Protein S6 Kinase 1 (S6K1) Signaling.
    Xu X, Jiang J, Yao L, Ji B.
    Med Sci Monit; 2018 Nov 11; 24():8064-8073. PubMed ID: 30415267
    [Abstract] [Full Text] [Related]

  • 15. Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation.
    Lee SJ, Yang EK, Kim SG.
    Mol Pharmacol; 2006 Jul 11; 70(1):415-25. PubMed ID: 16611854
    [Abstract] [Full Text] [Related]

  • 16. The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.
    Sheng YH, Leu WJ, Chen CN, Hsu JL, Liu YT, Hsu LC, Hou DR, Guh JH.
    Molecules; 2020 Jun 25; 25(12):. PubMed ID: 32630532
    [Abstract] [Full Text] [Related]

  • 17. Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1.
    Liu Y, Fanburg BL.
    Am J Respir Cell Mol Biol; 2006 Feb 25; 34(2):182-91. PubMed ID: 16195541
    [Abstract] [Full Text] [Related]

  • 18. Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway.
    Pang X, Yi Z, Zhang J, Lu B, Sung B, Qu W, Aggarwal BB, Liu M.
    Cancer Res; 2010 Mar 01; 70(5):1951-9. PubMed ID: 20160026
    [Abstract] [Full Text] [Related]

  • 19. S6K Promotes Dopaminergic Neuronal Differentiation Through PI3K/Akt/mTOR-Dependent Signaling Pathways in Human Neural Stem Cells.
    Lee JE, Lim MS, Park JH, Park CH, Koh HC.
    Mol Neurobiol; 2016 Aug 01; 53(6):3771-3782. PubMed ID: 26143260
    [Abstract] [Full Text] [Related]

  • 20. PRAS40 is an integral regulatory component of erythropoietin mTOR signaling and cytoprotection.
    Chong ZZ, Shang YC, Wang S, Maiese K.
    PLoS One; 2012 Aug 01; 7(9):e45456. PubMed ID: 23029019
    [Abstract] [Full Text] [Related]

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