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Journal Abstract Search

166 related items for PubMed ID: 22280812

  • 1. Novel pharmacological TRPC inhibitors block hypoxia-induced vasoconstriction.
    Urban N, Hill K, Wang L, Kuebler WM, Schaefer M.
    Cell Calcium; 2012 Feb; 51(2):194-206. PubMed ID: 22280812
    [Abstract] [Full Text] [Related]

  • 2. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.
    Urban N, Wang L, Kwiek S, Rademann J, Kuebler WM, Schaefer M.
    Mol Pharmacol; 2016 Jan; 89(1):197-213. PubMed ID: 26500253
    [Abstract] [Full Text] [Related]

  • 3. Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
    Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX.
    Am J Respir Cell Mol Biol; 2015 Sep; 53(3):355-67. PubMed ID: 25569851
    [Abstract] [Full Text] [Related]

  • 4. Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6.
    Fuchs B, Rupp M, Ghofrani HA, Schermuly RT, Seeger W, Grimminger F, Gudermann T, Dietrich A, Weissmann N.
    Respir Res; 2011 Feb 04; 12(1):20. PubMed ID: 21294865
    [Abstract] [Full Text] [Related]

  • 5. Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
    Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Storch U, Mederos y Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann T.
    Proc Natl Acad Sci U S A; 2006 Dec 12; 103(50):19093-8. PubMed ID: 17142322
    [Abstract] [Full Text] [Related]

  • 6. Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels.
    Maier T, Follmann M, Hessler G, Kleemann HW, Hachtel S, Fuchs B, Weissmann N, Linz W, Schmidt T, Löhn M, Schroeter K, Wang L, Rütten H, Strübing C.
    Br J Pharmacol; 2015 Jul 12; 172(14):3650-60. PubMed ID: 25847402
    [Abstract] [Full Text] [Related]

  • 7. CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.
    Tabeling C, Yu H, Wang L, Ranke H, Goldenberg NM, Zabini D, Noe E, Krauszman A, Gutbier B, Yin J, Schaefer M, Arenz C, Hocke AC, Suttorp N, Proia RL, Witzenrath M, Kuebler WM.
    Proc Natl Acad Sci U S A; 2015 Mar 31; 112(13):E1614-23. PubMed ID: 25829545
    [Abstract] [Full Text] [Related]

  • 8. Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel.
    Nishioka K, Nishida M, Ariyoshi M, Jian Z, Saiki S, Hirano M, Nakaya M, Sato Y, Kita S, Iwamoto T, Hirano K, Inoue R, Kurose H.
    Arterioscler Thromb Vasc Biol; 2011 Oct 31; 31(10):2278-86. PubMed ID: 21799177
    [Abstract] [Full Text] [Related]

  • 9. Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds.
    Sawamura S, Hatano M, Takada Y, Hino K, Kawamura T, Tanikawa J, Nakagawa H, Hase H, Nakao A, Hirano M, Rotrattanadumrong R, Kiyonaka S, Mori MX, Nishida M, Hu Y, Inoue R, Nagata R, Mori Y.
    Mol Pharmacol; 2016 Mar 31; 89(3):348-63. PubMed ID: 26733543
    [Abstract] [Full Text] [Related]

  • 10. Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension.
    Lin MJ, Leung GP, Zhang WM, Yang XR, Yip KP, Tse CM, Sham JS.
    Circ Res; 2004 Sep 03; 95(5):496-505. PubMed ID: 15256480
    [Abstract] [Full Text] [Related]

  • 11. Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension.
    Álvarez-Miguel I, Cidad P, Pérez-García MT, López-López JR.
    J Physiol; 2017 Mar 01; 595(5):1497-1513. PubMed ID: 27861908
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological inhibition of focal segmental glomerulosclerosis-related, gain of function mutants of TRPC6 channels by semi-synthetic derivatives of larixol.
    Urban N, Neuser S, Hentschel A, Köhling S, Rademann J, Schaefer M.
    Br J Pharmacol; 2017 Nov 01; 174(22):4099-4122. PubMed ID: 28800680
    [Abstract] [Full Text] [Related]

  • 13. TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction.
    Goldenberg NM, Wang L, Ranke H, Liedtke W, Tabuchi A, Kuebler WM.
    Anesthesiology; 2015 Jun 01; 122(6):1338-48. PubMed ID: 25815455
    [Abstract] [Full Text] [Related]

  • 14. Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells.
    Wang J, Weigand L, Lu W, Sylvester JT, Semenza GL, Shimoda LA.
    Circ Res; 2006 Jun 23; 98(12):1528-37. PubMed ID: 16709899
    [Abstract] [Full Text] [Related]

  • 15. Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions.
    Xia Y, Yang XR, Fu Z, Paudel O, Abramowitz J, Birnbaumer L, Sham JS.
    Hypertension; 2014 Jan 23; 63(1):173-80. PubMed ID: 24144647
    [Abstract] [Full Text] [Related]

  • 16. Calcium sensing receptor modulates extracellular calcium entry and proliferation via TRPC3/6 channels in cultured human mesangial cells.
    Meng K, Xu J, Zhang C, Zhang R, Yang H, Liao C, Jiao J.
    PLoS One; 2014 Jan 23; 9(6):e98777. PubMed ID: 24905090
    [Abstract] [Full Text] [Related]

  • 17. TRPC6 is required for hypoxia-induced basal intracellular calcium concentration elevation, and for the proliferation and migration of rat distal pulmonary venous smooth muscle cells.
    Wang Q, Wang D, Yan G, Sun L, Tang C.
    Mol Med Rep; 2016 Feb 23; 13(2):1577-85. PubMed ID: 26718737
    [Abstract] [Full Text] [Related]

  • 18. Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
    Guo W, Tang Q, Wei M, Kang Y, Wu JX, Chen L.
    Neuron; 2022 Mar 16; 110(6):1023-1035.e5. PubMed ID: 35051376
    [Abstract] [Full Text] [Related]

  • 19. Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels.
    Häfner S, Urban N, Schaefer M.
    Cell Calcium; 2019 Mar 16; 78():26-34. PubMed ID: 30594060
    [Abstract] [Full Text] [Related]

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