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996 related items for PubMed ID: 22281388

  • 1. Embryonic stem cell trials for macular degeneration: a preliminary report.
    Schwartz SD, Hubschman JP, Heilwell G, Franco-Cardenas V, Pan CK, Ostrick RM, Mickunas E, Gay R, Klimanskaya I, Lanza R.
    Lancet; 2012 Feb 25; 379(9817):713-20. PubMed ID: 22281388
    [Abstract] [Full Text] [Related]

  • 2. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies.
    Schwartz SD, Regillo CD, Lam BL, Eliott D, Rosenfeld PJ, Gregori NZ, Hubschman JP, Davis JL, Heilwell G, Spirn M, Maguire J, Gay R, Bateman J, Ostrick RM, Morris D, Vincent M, Anglade E, Del Priore LV, Lanza R.
    Lancet; 2015 Feb 07; 385(9967):509-16. PubMed ID: 25458728
    [Abstract] [Full Text] [Related]

  • 3. Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration.
    Mehat MS, Sundaram V, Ripamonti C, Robson AG, Smith AJ, Borooah S, Robinson M, Rosenthal AN, Innes W, Weleber RG, Lee RWJ, Crossland M, Rubin GS, Dhillon B, Steel DHW, Anglade E, Lanza RP, Ali RR, Michaelides M, Bainbridge JWB.
    Ophthalmology; 2018 Nov 07; 125(11):1765-1775. PubMed ID: 29884405
    [Abstract] [Full Text] [Related]

  • 4. Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration.
    Lu B, Malcuit C, Wang S, Girman S, Francis P, Lemieux L, Lanza R, Lund R.
    Stem Cells; 2009 Sep 07; 27(9):2126-35. PubMed ID: 19521979
    [Abstract] [Full Text] [Related]

  • 5. Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration.
    da Cruz L, Fynes K, Georgiadis O, Kerby J, Luo YH, Ahmado A, Vernon A, Daniels JT, Nommiste B, Hasan SM, Gooljar SB, Carr AF, Vugler A, Ramsden CM, Bictash M, Fenster M, Steer J, Harbinson T, Wilbrey A, Tufail A, Feng G, Whitlock M, Robson AG, Holder GE, Sagoo MS, Loudon PT, Whiting P, Coffey PJ.
    Nat Biotechnol; 2018 Apr 07; 36(4):328-337. PubMed ID: 29553577
    [Abstract] [Full Text] [Related]

  • 6. Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation.
    Vugler A, Carr AJ, Lawrence J, Chen LL, Burrell K, Wright A, Lundh P, Semo M, Ahmado A, Gias C, da Cruz L, Moore H, Andrews P, Walsh J, Coffey P.
    Exp Neurol; 2008 Dec 07; 214(2):347-61. PubMed ID: 18926821
    [Abstract] [Full Text] [Related]

  • 7. Long-term safety and tolerability of subretinal transplantation of embryonic stem cell-derived retinal pigment epithelium in Asian Stargardt disease patients.
    Sung Y, Lee MJ, Choi J, Jung SY, Chong SY, Sung JH, Shim SH, Song WK.
    Br J Ophthalmol; 2021 Jun 07; 105(6):829-837. PubMed ID: 32727729
    [Abstract] [Full Text] [Related]

  • 8. Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients.
    Song WK, Park KM, Kim HJ, Lee JH, Choi J, Chong SY, Shim SH, Del Priore LV, Lanza R.
    Stem Cell Reports; 2015 May 12; 4(5):860-72. PubMed ID: 25937371
    [Abstract] [Full Text] [Related]

  • 9. Stem cell based therapies for age-related macular degeneration: The promises and the challenges.
    Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS.
    Prog Retin Eye Res; 2015 Sep 12; 48():1-39. PubMed ID: 26113213
    [Abstract] [Full Text] [Related]

  • 10. Stem Cell-Based Therapy for Diseases of the Retinal Pigment Epithelium: From Bench to Bedside.
    Sachdeva MM, Eliott D.
    Semin Ophthalmol; 2016 Sep 12; 31(1-2):25-9. PubMed ID: 26959126
    [Abstract] [Full Text] [Related]

  • 11. Subretinal Transplantation of Embryonic Stem Cell-Derived Retinal Pigment Epithelium for the Treatment of Macular Degeneration: An Assessment at 4 Years.
    Schwartz SD, Tan G, Hosseini H, Nagiel A.
    Invest Ophthalmol Vis Sci; 2016 Apr 01; 57(5):ORSFc1-9. PubMed ID: 27116660
    [Abstract] [Full Text] [Related]

  • 12. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.
    Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS.
    Sci Transl Med; 2018 Apr 04; 10(435):. PubMed ID: 29618560
    [Abstract] [Full Text] [Related]

  • 13. A phase I clinical trial of human embryonic stem cell-derived retinal pigment epithelial cells for early-stage Stargardt macular degeneration: 5-years' follow-up.
    Li SY, Liu Y, Wang L, Wang F, Zhao TT, Li QY, Xu HW, Meng XH, Hao J, Zhou Q, Wang L, Yin ZQ.
    Cell Prolif; 2021 Sep 04; 54(9):e13100. PubMed ID: 34347352
    [Abstract] [Full Text] [Related]

  • 14. The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue.
    Davis RJ, Alam NM, Zhao C, Müller C, Saini JS, Blenkinsop TA, Mazzoni F, Campbell M, Borden SM, Charniga CJ, Lederman PL, Aguilar V, Naimark M, Fiske M, Boles N, Temple S, Finnemann SC, Prusky GT, Stern JH.
    Stem Cell Reports; 2017 Jul 11; 9(1):42-49. PubMed ID: 28625537
    [Abstract] [Full Text] [Related]

  • 15. Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer.
    Diniz B, Thomas P, Thomas B, Ribeiro R, Hu Y, Brant R, Ahuja A, Zhu D, Liu L, Koss M, Maia M, Chader G, Hinton DR, Humayun MS.
    Invest Ophthalmol Vis Sci; 2013 Jul 26; 54(7):5087-96. PubMed ID: 23833067
    [Abstract] [Full Text] [Related]

  • 16. Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium.
    Choudhary P, Gutteridge A, Impey E, Storer RI, Owen RM, Whiting PJ, Bictash M, Benn CL.
    Stem Cells Transl Med; 2016 Jul 26; 5(7):925-37. PubMed ID: 27112176
    [Abstract] [Full Text] [Related]

  • 17. Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate.
    Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.
    Stem Cells Transl Med; 2015 Feb 26; 4(2):165-77. PubMed ID: 25593208
    [Abstract] [Full Text] [Related]

  • 18. Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy.
    Petrus-Reurer S, Bartuma H, Aronsson M, Westman S, Lanner F, Kvanta A.
    J Vis Exp; 2018 Jan 22; (131):. PubMed ID: 29443034
    [Abstract] [Full Text] [Related]

  • 19. Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins.
    Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.
    J Tissue Eng Regen Med; 2013 Aug 22; 7(8):642-53. PubMed ID: 22514096
    [Abstract] [Full Text] [Related]

  • 20. Survival and functionality of xeno-free human embryonic stem cell-derived retinal pigment epithelial cells on polyester substrate after transplantation in rabbits.
    Ilmarinen T, Thieltges F, Hongisto H, Juuti-Uusitalo K, Koistinen A, Kaarniranta K, Brinken R, Braun N, Holz FG, Skottman H, Stanzel BV.
    Acta Ophthalmol; 2019 Aug 22; 97(5):e688-e699. PubMed ID: 30593729
    [Abstract] [Full Text] [Related]

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