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Journal Abstract Search


176 related items for PubMed ID: 22286559

  • 1. Synthesis of N-substituted ε-hexonolactams as pharmacological chaperones for the treatment of N370S mutant Gaucher disease.
    Wang GN, Twigg G, Butters TD, Zhang S, Zhang L, Zhang LH, Ye XS.
    Org Biomol Chem; 2012 Apr 21; 10(15):2923-7. PubMed ID: 22286559
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  • 2. Rational design and synthesis of highly potent pharmacological chaperones for treatment of N370S mutant Gaucher disease.
    Wang GN, Reinkensmeier G, Zhang SW, Zhou J, Zhang LR, Zhang LH, Butters TD, Ye XS.
    J Med Chem; 2009 May 28; 52(10):3146-9. PubMed ID: 19397268
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  • 4. Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.
    Yu L, Ikeda K, Kato A, Adachi I, Godin G, Compain P, Martin O, Asano N.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7736-44. PubMed ID: 16919960
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  • 5. Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)deoxynojirimycin.
    Luan Z, Higaki K, Aguilar-Moncayo M, Ninomiya H, Ohno K, García-Moreno MI, Ortiz Mellet C, García Fernández JM, Suzuki Y.
    Chembiochem; 2009 Nov 23; 10(17):2780-92. PubMed ID: 19830760
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  • 11. A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.
    Thirumal Kumar D, Iyer S, Christy JP, Siva R, Tayubi IA, George Priya Doss C, Zayed H.
    Adv Protein Chem Struct Biol; 2019 Nov 23; 114():315-339. PubMed ID: 30635084
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  • 14. Glucocerebrosidase inhibitors for the treatment of Gaucher disease.
    Trapero A, Llebaria A.
    Future Med Chem; 2013 Apr 23; 5(5):573-90. PubMed ID: 23573974
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  • 15. Human Acid β-Glucosidase Inhibition by Carbohydrate Derived Iminosugars: Towards New Pharmacological Chaperones for Gaucher Disease.
    Parmeggiani C, Catarzi S, Matassini C, D'Adamio G, Morrone A, Goti A, Paoli P, Cardona F.
    Chembiochem; 2015 Sep 21; 16(14):2054-64. PubMed ID: 26376302
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  • 16. Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease.
    Sawkar AR, Cheng WC, Beutler E, Wong CH, Balch WE, Kelly JW.
    Proc Natl Acad Sci U S A; 2002 Nov 26; 99(24):15428-33. PubMed ID: 12434014
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  • 18. Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease.
    Kato A, Nakagome I, Sato K, Yamamoto A, Adachi I, Nash RJ, Fleet GW, Natori Y, Watanabe Y, Imahori T, Yoshimura Y, Takahata H, Hirono S.
    Org Biomol Chem; 2016 Jan 21; 14(3):1039-48. PubMed ID: 26633162
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  • 19. A Fluorescent sp2-iminosugar with pharmacological chaperone activity for gaucher disease: synthesis and intracellular distribution studies.
    Luan Z, Higaki K, Aguilar-Moncayo M, Li L, Ninomiya H, Nanba E, Ohno K, García-Moreno MI, Ortiz Mellet C, García Fernández JM, Suzuki Y.
    Chembiochem; 2010 Nov 22; 11(17):2453-64. PubMed ID: 21064079
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  • 20. Aminocyclitols as pharmacological chaperones for glucocerebrosidase, a defective enzyme in Gaucher disease.
    Egido-Gabás M, Canals D, Casas J, Llebaria A, Delgado A.
    ChemMedChem; 2007 Jul 22; 2(7):992-4. PubMed ID: 17479993
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