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273 related items for PubMed ID: 22342571

  • 1. CIP2A-mediated Akt activation plays a role in bortezomib-induced apoptosis in head and neck squamous cell carcinoma cells.
    Lin YC, Chen KC, Chen CC, Cheng AL, Chen KF.
    Oral Oncol; 2012 Jul; 48(7):585-93. PubMed ID: 22342571
    [Abstract] [Full Text] [Related]

  • 2. CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells.
    Chen KF, Liu CY, Lin YC, Yu HC, Liu TH, Hou DR, Chen PJ, Cheng AL.
    Oncogene; 2010 Nov 25; 29(47):6257-66. PubMed ID: 20729919
    [Abstract] [Full Text] [Related]

  • 3. Synergistic interactions between sorafenib and bortezomib in hepatocellular carcinoma involve PP2A-dependent Akt inactivation.
    Chen KF, Yu HC, Liu TH, Lee SS, Chen PJ, Cheng AL.
    J Hepatol; 2010 Jan 25; 52(1):88-95. PubMed ID: 19913321
    [Abstract] [Full Text] [Related]

  • 4. CIP2A is a target of bortezomib in human triple negative breast cancer cells.
    Tseng LM, Liu CY, Chang KC, Chu PY, Shiau CW, Chen KF.
    Breast Cancer Res; 2012 Apr 26; 14(2):R68. PubMed ID: 22537901
    [Abstract] [Full Text] [Related]

  • 5. Bortezomib sensitizes HCC cells to CS-1008, an antihuman death receptor 5 antibody, through the inhibition of CIP2A.
    Chen KF, Yu HC, Liu CY, Chen HJ, Chen YC, Hou DR, Chen PJ, Cheng AL.
    Mol Cancer Ther; 2011 May 26; 10(5):892-901. PubMed ID: 21393428
    [Abstract] [Full Text] [Related]

  • 6. Down-regulation of phospho-Akt is a major molecular determinant of bortezomib-induced apoptosis in hepatocellular carcinoma cells.
    Chen KF, Yeh PY, Yeh KH, Lu YS, Huang SY, Cheng AL.
    Cancer Res; 2008 Aug 15; 68(16):6698-707. PubMed ID: 18701494
    [Abstract] [Full Text] [Related]

  • 7. Cancerous inhibitor of protein phosphatase 2A determines bortezomib-induced apoptosis in leukemia cells.
    Liu CY, Shiau CW, Kuo HY, Huang HP, Chen MH, Tzeng CH, Chen KF.
    Haematologica; 2013 May 15; 98(5):729-38. PubMed ID: 22983581
    [Abstract] [Full Text] [Related]

  • 8. Bortezomib-induced apoptosis with limited clinical response is accompanied by inhibition of canonical but not alternative nuclear factor-{kappa}B subunits in head and neck cancer.
    Allen C, Saigal K, Nottingham L, Arun P, Chen Z, Van Waes C.
    Clin Cancer Res; 2008 Jul 01; 14(13):4175-85. PubMed ID: 18593997
    [Abstract] [Full Text] [Related]

  • 9. Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome.
    Yu HC, Hou DR, Liu CY, Lin CS, Shiau CW, Cheng AL, Chen KF.
    PLoS One; 2013 Jul 01; 8(2):e55705. PubMed ID: 23383345
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of CIP2A determines erlotinib-induced apoptosis in hepatocellular carcinoma.
    Yu HC, Chen HJ, Chang YL, Liu CY, Shiau CW, Cheng AL, Chen KF.
    Biochem Pharmacol; 2013 Feb 01; 85(3):356-66. PubMed ID: 23178652
    [Abstract] [Full Text] [Related]

  • 11. Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells.
    Liu CY, Hu MH, Hsu CJ, Huang CT, Wang DS, Tsai WC, Chen YT, Lee CH, Chu PY, Hsu CC, Chen MH, Shiau CW, Tseng LM, Chen KF.
    Oncotarget; 2016 Feb 23; 7(8):9135-49. PubMed ID: 26824320
    [Abstract] [Full Text] [Related]

  • 12. Bortezomib enhances radiation-induced apoptosis in solid tumors by inhibiting CIP2A.
    Huang CY, Wei CC, Chen KC, Chen HJ, Cheng AL, Chen KF.
    Cancer Lett; 2012 Apr 01; 317(1):9-15. PubMed ID: 22085493
    [Abstract] [Full Text] [Related]

  • 13. Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells.
    Fribley A, Zeng Q, Wang CY.
    Mol Cell Biol; 2004 Nov 01; 24(22):9695-704. PubMed ID: 15509775
    [Abstract] [Full Text] [Related]

  • 14. Nuclear factor-kappaB pathway as a therapeutic target in head and neck squamous cell carcinoma: pharmaceutical and molecular validation in human cell lines using Velcade and siRNA/NF-kappaB.
    Lun M, Zhang PL, Pellitteri PK, Law A, Kennedy TL, Brown RE.
    Ann Clin Lab Sci; 2005 Nov 01; 35(3):251-8. PubMed ID: 16081580
    [Abstract] [Full Text] [Related]

  • 15. Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Chen KF, Yeh PY, Hsu C, Hsu CH, Lu YS, Hsieh HP, Chen PJ, Cheng AL.
    J Biol Chem; 2009 Apr 24; 284(17):11121-33. PubMed ID: 19261616
    [Abstract] [Full Text] [Related]

  • 16. PS-341 and histone deacetylase inhibitor synergistically induce apoptosis in head and neck squamous cell carcinoma cells.
    Kim J, Guan J, Chang I, Chen X, Han D, Wang CY.
    Mol Cancer Ther; 2010 Jul 24; 9(7):1977-84. PubMed ID: 20571067
    [Abstract] [Full Text] [Related]

  • 17. Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells.
    Liu CY, Hung MH, Wang DS, Chu PY, Su JC, Teng TH, Huang CT, Chao TT, Wang CY, Shiau CW, Tseng LM, Chen KF.
    Breast Cancer Res; 2014 Sep 17; 16(5):431. PubMed ID: 25228280
    [Abstract] [Full Text] [Related]

  • 18. Erlotinib derivative inhibits hepatocellular carcinoma by targeting CIP2A to reactivate protein phosphatase 2A.
    Yu HC, Hung MH, Chen YL, Chu PY, Wang CY, Chao TT, Liu CY, Shiau CW, Chen KF.
    Cell Death Dis; 2014 Jul 31; 5(7):e1359. PubMed ID: 25077545
    [Abstract] [Full Text] [Related]

  • 19. Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells.
    Li C, Li R, Grandis JR, Johnson DE.
    Mol Cancer Ther; 2008 Jun 31; 7(6):1647-55. PubMed ID: 18566236
    [Abstract] [Full Text] [Related]

  • 20. Role of CIP2A in the antitumor effect of bortezomib in colon cancer.
    Ding Y, Wang Y, Ju S, Wu X, Zhu W, Shi F, Mao L.
    Mol Med Rep; 2014 Jul 31; 10(1):387-92. PubMed ID: 24789441
    [Abstract] [Full Text] [Related]

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