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404 related items for PubMed ID: 22343031

  • 1. Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.
    Holopainen T, Saharinen P, D'Amico G, Lampinen A, Eklund L, Sormunen R, Anisimov A, Zarkada G, Lohela M, Heloterä H, Tammela T, Benjamin LE, Ylä-Herttuala S, Leow CC, Koh GY, Alitalo K.
    J Natl Cancer Inst; 2012 Mar 21; 104(6):461-75. PubMed ID: 22343031
    [Abstract] [Full Text] [Related]

  • 2. Angiopoietin2 and tie2: tied to lymphangiogenesis and lung metastasis. New perspectives in antimetastatic antiangiogenic therapy.
    Albini A, Noonan DM.
    J Natl Cancer Inst; 2012 Mar 21; 104(6):429-31. PubMed ID: 22343030
    [No Abstract] [Full Text] [Related]

  • 3. MEDI3617, a human anti-angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models.
    Leow CC, Coffman K, Inigo I, Breen S, Czapiga M, Soukharev S, Gingles N, Peterson N, Fazenbaker C, Woods R, Jallal B, Ricketts SA, Lavallee T, Coats S, Chang Y.
    Int J Oncol; 2012 May 21; 40(5):1321-30. PubMed ID: 22327175
    [Abstract] [Full Text] [Related]

  • 4. Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions.
    Zheng W, Nurmi H, Appak S, Sabine A, Bovay E, Korhonen EA, Orsenigo F, Lohela M, D'Amico G, Holopainen T, Leow CC, Dejana E, Petrova TV, Augustin HG, Alitalo K.
    Genes Dev; 2014 Jul 15; 28(14):1592-603. PubMed ID: 25030698
    [Abstract] [Full Text] [Related]

  • 5. Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.
    Falcón BL, Hashizume H, Koumoutsakos P, Chou J, Bready JV, Coxon A, Oliner JD, McDonald DM.
    Am J Pathol; 2009 Nov 15; 175(5):2159-70. PubMed ID: 19815705
    [Abstract] [Full Text] [Related]

  • 6. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.
    He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, Alitalo K.
    J Natl Cancer Inst; 2002 Jun 05; 94(11):819-25. PubMed ID: 12048269
    [Abstract] [Full Text] [Related]

  • 7. Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition.
    Daly C, Eichten A, Castanaro C, Pasnikowski E, Adler A, Lalani AS, Papadopoulos N, Kyle AH, Minchinton AI, Yancopoulos GD, Thurston G.
    Cancer Res; 2013 Jan 01; 73(1):108-18. PubMed ID: 23149917
    [Abstract] [Full Text] [Related]

  • 8. Angiopoietin-2 TIEs up macrophages in tumor angiogenesis.
    De Palma M, Naldini L.
    Clin Cancer Res; 2011 Aug 15; 17(16):5226-32. PubMed ID: 21576085
    [Abstract] [Full Text] [Related]

  • 9. Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth.
    Huang H, Lai JY, Do J, Liu D, Li L, Del Rosario J, Doppalapudi VR, Pirie-Shepherd S, Levin N, Bradshaw C, Woodnutt G, Lappe R, Bhat A.
    Clin Cancer Res; 2011 Mar 01; 17(5):1001-11. PubMed ID: 21233403
    [Abstract] [Full Text] [Related]

  • 10. A collagen IV-derived peptide disrupts α5β1 integrin and potentiates Ang2/Tie2 signaling.
    Mirando AC, Shen J, Silva RLE, Chu Z, Sass NC, Lorenc VE, Green JJ, Campochiaro PA, Popel AS, Pandey NB.
    JCI Insight; 2019 Feb 21; 4(4):. PubMed ID: 30668550
    [Abstract] [Full Text] [Related]

  • 11. Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
    Hakanpaa L, Sipila T, Leppanen VM, Gautam P, Nurmi H, Jacquemet G, Eklund L, Ivaska J, Alitalo K, Saharinen P.
    Nat Commun; 2015 Jan 30; 6():5962. PubMed ID: 25635707
    [Abstract] [Full Text] [Related]

  • 12. Crosstalk between TEMs and endothelial cells modulates angiogenesis and metastasis via IGF1-IGF1R signalling in epithelial ovarian cancer.
    Wang X, Zhu Q, Lin Y, Wu L, Wu X, Wang K, He Q, Xu C, Wan X, Wang X.
    Br J Cancer; 2017 Oct 24; 117(9):1371-1382. PubMed ID: 28898232
    [Abstract] [Full Text] [Related]

  • 13. Blocking Angiopoietin-2 Promotes Vascular Damage and Growth Inhibition in Mouse Tumors Treated with Small Doses of Radiation.
    Kallio P, Jokinen E, Högström J, Das S, Heino S, Lähde M, Brodkin J, Korhonen EA, Alitalo K.
    Cancer Res; 2020 Jun 15; 80(12):2639-2650. PubMed ID: 32312835
    [Abstract] [Full Text] [Related]

  • 14. Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization.
    Takagi H, Koyama S, Seike H, Oh H, Otani A, Matsumura M, Honda Y.
    Invest Ophthalmol Vis Sci; 2003 Jan 15; 44(1):393-402. PubMed ID: 12506101
    [Abstract] [Full Text] [Related]

  • 15. Tie1 regulates the Tie2 agonistic role of angiopoietin-2 in human lymphatic endothelial cells.
    Song SH, Kim KL, Lee KA, Suh W.
    Biochem Biophys Res Commun; 2012 Mar 09; 419(2):281-6. PubMed ID: 22342979
    [Abstract] [Full Text] [Related]

  • 16. Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology.
    Akwii RG, Sajib MS, Zahra FT, Mikelis CM.
    Cells; 2019 May 17; 8(5):. PubMed ID: 31108880
    [Abstract] [Full Text] [Related]

  • 17. Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis.
    Gengenbacher N, Singhal M, Mogler C, Hai L, Milde L, Pari AAA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG.
    Cancer Discov; 2021 Feb 17; 11(2):424-445. PubMed ID: 33106316
    [Abstract] [Full Text] [Related]

  • 18. Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis.
    Chang CC, Lin MT, Lin BR, Jeng YM, Chen ST, Chu CY, Chen RJ, Chang KJ, Yang PC, Kuo ML.
    J Natl Cancer Inst; 2006 Jul 19; 98(14):984-95. PubMed ID: 16849681
    [Abstract] [Full Text] [Related]

  • 19. Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.
    Kim M, Allen B, Korhonen EA, Nitschké M, Yang HW, Baluk P, Saharinen P, Alitalo K, Daly C, Thurston G, McDonald DM.
    J Clin Invest; 2016 Sep 01; 126(9):3511-25. PubMed ID: 27548529
    [Abstract] [Full Text] [Related]

  • 20. LncRNA EPIC1 promotes tumor angiogenesis via activating the Ang2/Tie2 axis in non-small cell lung cancer.
    Hou Y, Jia H, Cao Y, Zhang S, Zhang X, Wei P, Xie J, Dong W, Wang B.
    Life Sci; 2021 Feb 15; 267():118933. PubMed ID: 33359744
    [Abstract] [Full Text] [Related]

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