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1985 related items for PubMed ID: 22343943

  • 1. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
    Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Erdin S, Huynh T, Ferron M, Karsenty G, Vellard MC, Facchinetti V, Sabatini DM, Ballabio A.
    EMBO J; 2012 Mar 07; 31(5):1095-108. PubMed ID: 22343943
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  • 3. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S, Ni HM, Chao X, Wang H, Bridges B, Kumer S, Schmitt T, Mareninova O, Gukovskaya A, De Lisle RC, Ballabio A, Pacher P, Ding WX.
    Autophagy; 2019 Nov 07; 15(11):1954-1969. PubMed ID: 30894069
    [Abstract] [Full Text] [Related]

  • 4. Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.
    Tanaka Y, Matsuwaki T, Yamanouchi K, Nishihara M.
    Neuroscience; 2013 Oct 10; 250():8-19. PubMed ID: 23830905
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  • 5. Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation.
    Lin J, Shi SS, Zhang JQ, Zhang YJ, Zhang L, Liu Y, Jin PP, Wei PF, Shi RH, Zhou W, Wen LP.
    Small; 2016 Nov 10; 12(41):5759-5768. PubMed ID: 27593892
    [Abstract] [Full Text] [Related]

  • 6. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.
    Martina JA, Chen Y, Gucek M, Puertollano R.
    Autophagy; 2012 Jun 10; 8(6):903-14. PubMed ID: 22576015
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  • 7. Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes.
    Martina JA, Puertollano R.
    J Cell Biol; 2013 Feb 18; 200(4):475-91. PubMed ID: 23401004
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  • 8. Multistep regulation of TFEB by MTORC1.
    Vega-Rubin-de-Celis S, Peña-Llopis S, Konda M, Brugarolas J.
    Autophagy; 2017 Mar 04; 13(3):464-472. PubMed ID: 28055300
    [Abstract] [Full Text] [Related]

  • 9. Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response.
    Jeong SJ, Stitham J, Evans TD, Zhang X, Rodriguez-Velez A, Yeh YS, Tao J, Takabatake K, Epelman S, Lodhi IJ, Schilling JD, DeBosch BJ, Diwan A, Razani B.
    Autophagy; 2021 Nov 04; 17(11):3740-3752. PubMed ID: 33706671
    [Abstract] [Full Text] [Related]

  • 10. Curcumin targets the TFEB-lysosome pathway for induction of autophagy.
    Zhang J, Wang J, Xu J, Lu Y, Jiang J, Wang L, Shen HM, Xia D.
    Oncotarget; 2016 Nov 15; 7(46):75659-75671. PubMed ID: 27689333
    [Abstract] [Full Text] [Related]

  • 11. The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis.
    Krishan S, Sahni S, Richardson DR.
    Biochim Biophys Acta Mol Basis Dis; 2020 Dec 01; 1866(12):165970. PubMed ID: 32950675
    [Abstract] [Full Text] [Related]

  • 12. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity.
    Zhitomirsky B, Yunaev A, Kreiserman R, Kaplan A, Stark M, Assaraf YG.
    Cell Death Dis; 2018 Dec 13; 9(12):1191. PubMed ID: 30546014
    [Abstract] [Full Text] [Related]

  • 13. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation.
    Wu M, Lao YZ, Tan HS, Lu G, Ren Y, Zheng ZQ, Yi J, Fu WW, Shen HM, Xu HX.
    Acta Pharmacol Sin; 2019 Jul 13; 40(7):929-937. PubMed ID: 30333555
    [Abstract] [Full Text] [Related]

  • 14. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.
    Wang W, Xia Z, Farré JC, Subramani S.
    Autophagy; 2018 Jul 13; 14(9):1574-1585. PubMed ID: 29940807
    [Abstract] [Full Text] [Related]

  • 15. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
    Zhou J, Tan SH, Nicolas V, Bauvy C, Yang ND, Zhang J, Xue Y, Codogno P, Shen HM.
    Cell Res; 2013 Apr 13; 23(4):508-23. PubMed ID: 23337583
    [Abstract] [Full Text] [Related]

  • 16. SMURF1 controls the PPP3/calcineurin complex and TFEB at a regulatory node for lysosomal biogenesis.
    Xia Q, Zheng H, Li Y, Xu W, Wu C, Xu J, Li S, Zhang L, Dong L.
    Autophagy; 2024 Apr 13; 20(4):735-751. PubMed ID: 37909662
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  • 20. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity.
    Pi H, Li M, Tian L, Yang Z, Yu Z, Zhou Z.
    Sci Rep; 2017 Feb 27; 7():43466. PubMed ID: 28240313
    [Abstract] [Full Text] [Related]

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