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141 related items for PubMed ID: 22348828

  • 1. Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors.
    Rubio-Ruíz B, Conejo-García A, Ríos-Marco P, Carrasco-Jiménez MP, Segovia J, Marco C, Gallo MA, Espinosa A, Entrena A.
    Eur J Med Chem; 2012 Apr; 50():154-62. PubMed ID: 22348828
    [Abstract] [Full Text] [Related]

  • 2. New non-symmetrical choline kinase inhibitors.
    Schiaffino-Ortega S, López-Cara LC, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Espinosa A, Marco C, Entrena A.
    Bioorg Med Chem; 2013 Nov 15; 21(22):7146-54. PubMed ID: 24080101
    [Abstract] [Full Text] [Related]

  • 3. Towards a model for the inhibition of choline kinase by a new type of inhibitor.
    Conejo-García A, Entrena A, Campos JM, Sánchez-Martín RM, Gallo MA, Espinosa A.
    Eur J Med Chem; 2005 Mar 15; 40(3):315-9. PubMed ID: 15725501
    [Abstract] [Full Text] [Related]

  • 4. Choline kinase inhibitors as a novel approach for antiproliferative drug design.
    Hernández-Alcoceba R, Saniger L, Campos J, Núñez MC, Khaless F, Gallo MA, Espinosa A, Lacal JC.
    Oncogene; 1997 Nov 06; 15(19):2289-301. PubMed ID: 9393874
    [Abstract] [Full Text] [Related]

  • 5. Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line.
    Gómez-Pérez V, McSorley T, See Too WC, Konrad M, Campos JM.
    ChemMedChem; 2012 Apr 06; 7(4):663-9. PubMed ID: 22278967
    [Abstract] [Full Text] [Related]

  • 6. Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.
    Sánchez-Martín R, Campos JM, Conejo-García A, Cruz-López O, Báñez-Coronel M, Rodríguez-González A, Gallo MA, Lacal JC, Espinosa A.
    J Med Chem; 2005 May 05; 48(9):3354-63. PubMed ID: 15857141
    [Abstract] [Full Text] [Related]

  • 7. Potential choline kinase inhibitors: a molecular modeling study of bis-quinolinium compounds.
    Srivani P, Sastry GN.
    J Mol Graph Model; 2009 Feb 05; 27(6):676-88. PubMed ID: 19147382
    [Abstract] [Full Text] [Related]

  • 8. New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.
    Castro-Navas FF, Schiaffino-Ortega S, Carrasco-Jimenez MP, Ríos-Marco P, Marco C, Espinosa A, Gallo MA, Mariotto E, Basso G, Viola G, Entrena-Guadix A, López-Cara LC.
    Future Med Chem; 2015 Feb 05; 7(4):417-36. PubMed ID: 25875870
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).
    Schiaffino-Ortega S, Baglioni E, Mariotto E, Bortolozzi R, Serrán-Aguilera L, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Hurtado-Guerrero R, Marco C, Basso G, Viola G, Entrena A, López-Cara LC.
    Sci Rep; 2016 Mar 31; 6():23793. PubMed ID: 27029499
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of ChoK is an efficient antitumor strategy for Harvey-, Kirsten-, and N-ras-transformed cells.
    Ramírez de Molina A, Rodríguez-González A, Penalva V, Lucas L, Lacal JC.
    Biochem Biophys Res Commun; 2001 Jul 27; 285(4):873-9. PubMed ID: 11467831
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological activity of new bispyridinium salts of 4,4'-bispyridyl-5,5'-perfluoroalkyl-2,2'-bisoxazoles.
    Martín-Cantalejo Y, Sáez B, Monterde MI, Murillo MT, Braña MF.
    Eur J Med Chem; 2011 Nov 27; 46(11):5662-7. PubMed ID: 21996467
    [Abstract] [Full Text] [Related]

  • 12. LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase.
    Campos J, del Carmen Núñez M, Rodríguez V, Entrena A, Hernández-Alcoceba R, Fernández F, Lacal JC, Gallo MA, Espinosa A.
    Eur J Med Chem; 2001 Mar 27; 36(3):215-25. PubMed ID: 11337100
    [Abstract] [Full Text] [Related]

  • 13. Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors.
    Conejo-García A, Campos JM, Sánchez-Martín RM, Gallo MA, Espinosa A.
    J Med Chem; 2003 Aug 14; 46(17):3754-7. PubMed ID: 12904080
    [Abstract] [Full Text] [Related]

  • 14. QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?
    Campos J, Núñez MC, Conejo-García A, Sánchez-Martín RM, Hernández-Alcoceba R, Rodríguez-González A, Lacal JC, Gallo MA, Espinosa A.
    Curr Med Chem; 2003 Jul 14; 10(13):1095-112. PubMed ID: 12678804
    [Abstract] [Full Text] [Related]

  • 15. (Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs.
    Campos JM, Sánchez-Martín RM, Conejo-García A, Entrena A, Gallo MA, Espinosa A.
    Curr Med Chem; 2006 Jul 14; 13(11):1231-48. PubMed ID: 16712467
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents.
    Zhang XM, Qiu M, Sun J, Zhang YB, Yang YS, Wang XL, Tang JF, Zhu HL.
    Bioorg Med Chem; 2011 Nov 01; 19(21):6518-24. PubMed ID: 21962523
    [Abstract] [Full Text] [Related]

  • 17. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase.
    Conejo-García A, Báñez-Coronel M, Sánchez-Martín RM, Rodríguez-González A, Ramos A, Ramírez de Molina A, Espinosa A, Gallo MA, Campos JM, Lacal JC.
    J Med Chem; 2004 Oct 21; 47(22):5433-40. PubMed ID: 15481981
    [Abstract] [Full Text] [Related]

  • 18. Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.
    Ramírez de Molina A, Báñez-Coronel M, Gutiérrez R, Rodríguez-González A, Olmeda D, Megías D, Lacal JC.
    Cancer Res; 2004 Sep 15; 64(18):6732-9. PubMed ID: 15374991
    [Abstract] [Full Text] [Related]

  • 19. Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.
    Felczak K, Chen L, Wilson D, Williams J, Vince R, Petrelli R, Jayaram HN, Kusumanchi P, Kumar M, Pankiewicz KW.
    Bioorg Med Chem; 2011 Mar 01; 19(5):1594-605. PubMed ID: 21324702
    [Abstract] [Full Text] [Related]

  • 20. Antiplasmodial activity and mechanism of action of RSM-932A, a promising synergistic inhibitor of Plasmodium falciparum choline kinase.
    Zimmerman T, Moneriz C, Diez A, Bautista JM, Gómez Del Pulgar T, Cebrián A, Lacal JC.
    Antimicrob Agents Chemother; 2013 Dec 01; 57(12):5878-88. PubMed ID: 24041883
    [Abstract] [Full Text] [Related]

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