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376 related items for PubMed ID: 22351759

  • 1. Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
    Lee SH, Che X, Jeong JH, Choi JY, Lee YJ, Lee YH, Bae SC, Lee YM.
    J Biol Chem; 2012 Apr 27; 287(18):14760-71. PubMed ID: 22351759
    [Abstract] [Full Text] [Related]

  • 2. Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
    Fu C, Tyagi R, Chin AC, Rojas T, Li RJ, Guha P, Bernstein IA, Rao F, Xu R, Cha JY, Xu J, Snowman AM, Semenza GL, Snyder SH.
    Circ Res; 2018 Feb 02; 122(3):457-472. PubMed ID: 29279301
    [Abstract] [Full Text] [Related]

  • 3. ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.
    Zhu K, Jiao H, Li S, Cao H, Galson DL, Zhao Z, Zhao X, Lai Y, Fan J, Im HJ, Chen D, Xiao G.
    J Bone Miner Res; 2013 Sep 02; 28(9):1870-1884. PubMed ID: 23649506
    [Abstract] [Full Text] [Related]

  • 4. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 5. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X, Yao J, Wang F, Zhou M, Zhou Y, Wang H, Wei L, Zhao L, Li Z, Lu N, Guo Q.
    Toxicol Appl Pharmacol; 2013 Sep 01; 271(2):144-55. PubMed ID: 23707765
    [Abstract] [Full Text] [Related]

  • 6. Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.
    Jung DB, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Kim YC, Ahn KS, Chen CY, Kim SH.
    Biol Pharm Bull; 2011 Sep 01; 34(6):850-5. PubMed ID: 21628883
    [Abstract] [Full Text] [Related]

  • 7. STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.
    Jung JE, Kim HS, Lee CS, Shin YJ, Kim YN, Kang GH, Kim TY, Juhnn YS, Kim SJ, Park JW, Ye SK, Chung MH.
    Exp Mol Med; 2008 Oct 31; 40(5):479-85. PubMed ID: 18985005
    [Abstract] [Full Text] [Related]

  • 8. Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression.
    Kwon TG, Zhao X, Yang Q, Li Y, Ge C, Zhao G, Franceschi RT.
    J Cell Biochem; 2011 Dec 31; 112(12):3582-93. PubMed ID: 21793044
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  • 14. Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway.
    Yoo YG, Oh SH, Park ES, Cho H, Lee N, Park H, Kim DK, Yu DY, Seong JK, Lee MO.
    J Biol Chem; 2003 Oct 03; 278(40):39076-84. PubMed ID: 12855680
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  • 15. Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
    Aro E, Khatri R, Gerard-O'Riley R, Mangiavini L, Myllyharju J, Schipani E.
    J Biol Chem; 2012 Oct 26; 287(44):37134-44. PubMed ID: 22930750
    [Abstract] [Full Text] [Related]

  • 16. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
    Chintala S, Najrana T, Toth K, Cao S, Durrani FA, Pili R, Rustum YM.
    BMC Cancer; 2012 Jul 17; 12():293. PubMed ID: 22804960
    [Abstract] [Full Text] [Related]

  • 17. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ.
    Cell Cycle; 2012 Dec 01; 11(23):4462-73. PubMed ID: 23159849
    [Abstract] [Full Text] [Related]

  • 18. Inhibitor of DNA binding 1 activates vascular endothelial growth factor through enhancing the stability and activity of hypoxia-inducible factor-1alpha.
    Kim HJ, Chung H, Yoo YG, Kim H, Lee JY, Lee MO, Kong G.
    Mol Cancer Res; 2007 Apr 01; 5(4):321-9. PubMed ID: 17426247
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  • 19. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
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  • 20. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.
    Hum Pathol; 2007 Sep 16; 38(9):1310-20. PubMed ID: 17555795
    [Abstract] [Full Text] [Related]

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