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714 related items for PubMed ID: 22383097

  • 1. Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.
    Delima RD, Chua AC, Tirnitz-Parker JE, Gan EK, Croft KD, Graham RM, Olynyk JK, Trinder D.
    Hepatology; 2012 Aug; 56(2):585-93. PubMed ID: 22383097
    [Abstract] [Full Text] [Related]

  • 2. Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.
    Wallace DF, Summerville L, Crampton EM, Frazer DM, Anderson GJ, Subramaniam VN.
    Hepatology; 2009 Dec; 50(6):1992-2000. PubMed ID: 19824072
    [Abstract] [Full Text] [Related]

  • 3. Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
    Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE.
    Gastroenterology; 2011 Nov; 141(5):1907-14. PubMed ID: 21745449
    [Abstract] [Full Text] [Related]

  • 4. Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.
    Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
    Hepatology; 2016 Jan; 63(1):126-37. PubMed ID: 26406355
    [Abstract] [Full Text] [Related]

  • 5. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice.
    Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T.
    Hepatology; 2011 Apr; 53(4):1333-41. PubMed ID: 21480335
    [Abstract] [Full Text] [Related]

  • 6. Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2.
    Wallace DF, McDonald CJ, Ostini L, Subramaniam VN.
    Blood; 2011 Mar 10; 117(10):2960-6. PubMed ID: 21245482
    [Abstract] [Full Text] [Related]

  • 7. Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.
    Gao J, Chen J, Kramer M, Tsukamoto H, Zhang AS, Enns CA.
    Cell Metab; 2009 Mar 10; 9(3):217-27. PubMed ID: 19254567
    [Abstract] [Full Text] [Related]

  • 8. Hepatic iron deposition does not predict extrahepatic iron loading in mouse models of hereditary hemochromatosis.
    Subramaniam VN, McDonald CJ, Ostini L, Lusby PE, Wockner LF, Ramm GA, Wallace DF.
    Am J Pathol; 2012 Oct 10; 181(4):1173-9. PubMed ID: 22858058
    [Abstract] [Full Text] [Related]

  • 9. Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.
    Schmidt PJ, Fleming MD.
    Am J Hematol; 2012 Jun 10; 87(6):588-95. PubMed ID: 22460705
    [Abstract] [Full Text] [Related]

  • 10. Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway.
    Gehrke SG, Herrmann T, Kulaksiz H, Merle U, Bents K, Kaiser I, Riedel HD, Stremmel W.
    Digestion; 2005 Jun 10; 72(1):25-32. PubMed ID: 16103673
    [Abstract] [Full Text] [Related]

  • 11. [Pathophysiology and genetics of classic HFE (type 1) hemochromatosis].
    Loréal O, Ropert M, Mosser A, Déhais V, Deugnier Y, David V, Brissot P, Jouanolle AM.
    Presse Med; 2007 Sep 10; 36(9 Pt 2):1271-7. PubMed ID: 17521857
    [Abstract] [Full Text] [Related]

  • 12. Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
    Gao J, Chen J, De Domenico I, Koeller DM, Harding CO, Fleming RE, Koeberl DD, Enns CA.
    Blood; 2010 Apr 22; 115(16):3374-81. PubMed ID: 20177050
    [Abstract] [Full Text] [Related]

  • 13. Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice.
    McDonald CJ, Wallace DF, Ostini L, Subramaniam VN.
    Am J Physiol Gastrointest Liver Physiol; 2014 Jan 22; 306(2):G132-9. PubMed ID: 24284962
    [Abstract] [Full Text] [Related]

  • 14. Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.
    Neves JV, Olsson IA, Porto G, Rodrigues PN.
    Am J Physiol Gastrointest Liver Physiol; 2010 Apr 22; 298(4):G525-9. PubMed ID: 20110460
    [Abstract] [Full Text] [Related]

  • 15. The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.
    Schmidt PJ, Toran PT, Giannetti AM, Bjorkman PJ, Andrews NC.
    Cell Metab; 2008 Mar 22; 7(3):205-14. PubMed ID: 18316026
    [Abstract] [Full Text] [Related]

  • 16. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis.
    Nicolas G, Viatte L, Lou DQ, Bennoun M, Beaumont C, Kahn A, Andrews NC, Vaulont S.
    Nat Genet; 2003 May 22; 34(1):97-101. PubMed ID: 12704388
    [Abstract] [Full Text] [Related]

  • 17. Hepatic iron metabolism gene expression profiles in HFE associated hereditary hemochromatosis.
    Gleeson F, Ryan E, Barrett S, Russell J, Crowe J.
    Blood Cells Mol Dis; 2007 May 22; 38(1):37-44. PubMed ID: 17098454
    [Abstract] [Full Text] [Related]

  • 18. The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation.
    D'Alessio F, Hentze MW, Muckenthaler MU.
    J Hepatol; 2012 Nov 22; 57(5):1052-60. PubMed ID: 22728873
    [Abstract] [Full Text] [Related]

  • 19. Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.
    Wallace DF, Summerville L, Subramaniam VN.
    Gastroenterology; 2007 Jan 22; 132(1):301-10. PubMed ID: 17241880
    [Abstract] [Full Text] [Related]

  • 20. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis.
    Fleming RE, Ahmann JR, Migas MC, Waheed A, Koeffler HP, Kawabata H, Britton RS, Bacon BR, Sly WS.
    Proc Natl Acad Sci U S A; 2002 Aug 06; 99(16):10653-8. PubMed ID: 12134060
    [Abstract] [Full Text] [Related]

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