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Journal Abstract Search

391 related items for PubMed ID: 22383166

  • 1. From preclinical to human--prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example.
    Sinha VK, Snoeys J, Osselaer NV, Peer AV, Mackie C, Heald D.
    Biopharm Drug Dispos; 2012 Mar; 33(2):111-21. PubMed ID: 22383166
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  • 2. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.
    Chen Y, Jin JY, Mukadam S, Malhi V, Kenny JR.
    Biopharm Drug Dispos; 2012 Mar; 33(2):85-98. PubMed ID: 22228214
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  • 5. Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates - an evaluation and case study using GastroPlus.
    Heikkinen AT, Baneyx G, Caruso A, Parrott N.
    Eur J Pharm Sci; 2012 Sep 29; 47(2):375-86. PubMed ID: 22759901
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  • 6. Integration of dissolution into physiologically-based pharmacokinetic models III: PK-Sim®.
    Willmann S, Thelen K, Lippert J.
    J Pharm Pharmacol; 2012 Jul 29; 64(7):997-1007. PubMed ID: 22686345
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  • 7. Mechanism-based inhibition of cytochrome P450 enzymes: an evaluation of early decision making in vitro approaches and drug-drug interaction prediction methods.
    Grime KH, Bird J, Ferguson D, Riley RJ.
    Eur J Pharm Sci; 2009 Feb 15; 36(2-3):175-91. PubMed ID: 19013237
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  • 8. Prediction of drug-drug interaction potential using physiologically based pharmacokinetic modeling.
    Min JS, Bae SK.
    Arch Pharm Res; 2017 Dec 15; 40(12):1356-1379. PubMed ID: 29079968
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  • 9. PBPK models for the prediction of in vivo performance of oral dosage forms.
    Kostewicz ES, Aarons L, Bergstrand M, Bolger MB, Galetin A, Hatley O, Jamei M, Lloyd R, Pepin X, Rostami-Hodjegan A, Sjögren E, Tannergren C, Turner DB, Wagner C, Weitschies W, Dressman J.
    Eur J Pharm Sci; 2014 Jun 16; 57():300-21. PubMed ID: 24060672
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  • 10. Predictions of metabolic drug-drug interactions using physiologically based modelling: Two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil.
    Perdaems N, Blasco H, Vinson C, Chenel M, Whalley S, Cazade F, Bouzom F.
    Clin Pharmacokinet; 2010 Apr 16; 49(4):239-58. PubMed ID: 20214408
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  • 11. Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic model.
    Wagner C, Jantratid E, Kesisoglou F, Vertzoni M, Reppas C, B Dressman J.
    Eur J Pharm Biopharm; 2012 Sep 16; 82(1):127-38. PubMed ID: 22652546
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  • 12. IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
    Ahmad A, Pepin X, Aarons L, Wang Y, Darwich AS, Wood JM, Tannergren C, Karlsson E, Patterson C, Thörn H, Ruston L, Mattinson A, Carlert S, Berg S, Murphy D, Engman H, Laru J, Barker R, Flanagan T, Abrahamsson B, Budhdeo S, Franek F, Moir A, Hanisch G, Pathak SM, Turner D, Jamei M, Brown J, Good D, Vaidhyanathan S, Jackson C, Nicolas O, Beilles S, Nguefack JF, Louit G, Henrion L, Ollier C, Boulu L, Xu C, Heimbach T, Ren X, Lin W, Nguyen-Trung AT, Zhang J, He H, Wu F, Bolger MB, Mullin JM, van Osdol B, Szeto K, Korjamo T, Pappinen S, Tuunainen J, Zhu W, Xia B, Daublain P, Wong S, Varma MVS, Modi S, Schäfer KJ, Schmid K, Lloyd R, Patel A, Tistaert C, Bevernage J, Nguyen MA, Lindley D, Carr R, Rostami-Hodjegan A.
    Eur J Pharm Biopharm; 2020 Nov 16; 156():50-63. PubMed ID: 32805361
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  • 13. Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice.
    Johnson TN, Rostami-Hodjegan A.
    Paediatr Anaesth; 2011 Mar 16; 21(3):291-301. PubMed ID: 20497354
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  • 15. In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.
    Sjögren E, Thörn H, Tannergren C.
    Mol Pharm; 2016 Jun 06; 13(6):1763-78. PubMed ID: 26926043
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  • 18. Measurement and prediction of oral absorption.
    Keldenich J.
    Chem Biodivers; 2009 Nov 06; 6(11):2000-13. PubMed ID: 19937837
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  • 19. PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach.
    Poulin P, Jones RD, Jones HM, Gibson CR, Rowland M, Chien JY, Ring BJ, Adkison KK, Ku MS, He H, Vuppugalla R, Marathe P, Fischer V, Dutta S, Sinha VK, Björnsson T, Lavé T, Yates JW.
    J Pharm Sci; 2011 Oct 06; 100(10):4127-57. PubMed ID: 21541937
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  • 20. Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?
    Bouzom F, Ball K, Perdaems N, Walther B.
    Biopharm Drug Dispos; 2012 Mar 06; 33(2):55-71. PubMed ID: 22228149
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