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175 related items for PubMed ID: 22384273

  • 1. γ-Aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate, the creatine biosynthetic precursor, in rats.
    Tachikawa M, Ikeda S, Fujinawa J, Hirose S, Akanuma S, Hosoya K.
    PLoS One; 2012; 7(2):e32557. PubMed ID: 22384273
    [Abstract] [Full Text] [Related]

  • 2. Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain.
    Tachikawa M, Yashiki A, Akanuma SI, Matsukawa H, Ide S, Minami M, Hosoya KI.
    Neurochem Int; 2018 Feb; 113():1-7. PubMed ID: 29175673
    [Abstract] [Full Text] [Related]

  • 3. Involvement of γ-aminobutyric acid transporter 2 in the hepatic uptake of taurine in rats.
    Ikeda S, Tachikawa M, Akanuma S, Fujinawa J, Hosoya K.
    Am J Physiol Gastrointest Liver Physiol; 2012 Aug 01; 303(3):G291-7. PubMed ID: 22678999
    [Abstract] [Full Text] [Related]

  • 4. Hepatic uptake of gamma-butyrobetaine, a precursor of carnitine biosynthesis, in rats.
    Fujita M, Nakanishi T, Shibue Y, Kobayashi D, Moseley RH, Shirasaka Y, Tamai I.
    Am J Physiol Gastrointest Liver Physiol; 2009 Oct 01; 297(4):G681-6. PubMed ID: 19679820
    [Abstract] [Full Text] [Related]

  • 5. Monocarboxylate transporter 12 as a guanidinoacetate efflux transporter in renal proximal tubular epithelial cells.
    Jomura R, Tanno Y, Akanuma SI, Kubo Y, Tachikawa M, Hosoya KI.
    Biochim Biophys Acta Biomembr; 2020 Nov 01; 1862(11):183434. PubMed ID: 32781157
    [Abstract] [Full Text] [Related]

  • 6. Creatine synthesis: hepatic metabolism of guanidinoacetate and creatine in the rat in vitro and in vivo.
    da Silva RP, Nissim I, Brosnan ME, Brosnan JT.
    Am J Physiol Endocrinol Metab; 2009 Feb 01; 296(2):E256-61. PubMed ID: 19017728
    [Abstract] [Full Text] [Related]

  • 7. The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters.
    Tachikawa M, Kasai Y, Yokoyama R, Fujinawa J, Ganapathy V, Terasaki T, Hosoya K.
    J Neurochem; 2009 Oct 01; 111(2):499-509. PubMed ID: 19682207
    [Abstract] [Full Text] [Related]

  • 8. Expression and possible role of creatine transporter in the brain and at the blood-cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant.
    Tachikawa M, Fujinawa J, Takahashi M, Kasai Y, Fukaya M, Sakai K, Yamazaki M, Tomi M, Watanabe M, Sakimura K, Terasaki T, Hosoya K.
    J Neurochem; 2008 Nov 01; 107(3):768-78. PubMed ID: 18761709
    [Abstract] [Full Text] [Related]

  • 9. Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents.
    Zhou Y, Holmseth S, Guo C, Hassel B, Höfner G, Huitfeldt HS, Wanner KT, Danbolt NC.
    J Biol Chem; 2012 Oct 12; 287(42):35733-35746. PubMed ID: 22896705
    [Abstract] [Full Text] [Related]

  • 10. Alcohol consumption decreases rat hepatic creatine biosynthesis via altered guanidinoacetate methyltransferase activity.
    Kharbanda KK, Todero SL, Moats JC, Harris RM, Osna NA, Thomes PG, Tuma DJ.
    Alcohol Clin Exp Res; 2014 Mar 12; 38(3):641-8. PubMed ID: 24256608
    [Abstract] [Full Text] [Related]

  • 11. SLC6A and SLC16A family of transporters: Contribution to transport of creatine and creatine precursors in creatine biosynthesis and distribution.
    Jomura R, Akanuma SI, Tachikawa M, Hosoya KI.
    Biochim Biophys Acta Biomembr; 2022 Mar 01; 1864(3):183840. PubMed ID: 34921896
    [Abstract] [Full Text] [Related]

  • 12. Carnitine precursor γ-butyrobetaine is a novel substrate of the Na(+)- and Cl(-)-dependent GABA transporter Gat2.
    Nakanishi T, Fukuyama Y, Fujita M, Shirasaka Y, Tamai I.
    Drug Metab Pharmacokinet; 2011 Mar 01; 26(6):632-6. PubMed ID: 21997971
    [Abstract] [Full Text] [Related]

  • 13. Creatine synthesis: production of guanidinoacetate by the rat and human kidney in vivo.
    Edison EE, Brosnan ME, Meyer C, Brosnan JT.
    Am J Physiol Renal Physiol; 2007 Dec 01; 293(6):F1799-804. PubMed ID: 17928413
    [Abstract] [Full Text] [Related]

  • 14. Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF.
    Jomura R, Akanuma SI, Kubo Y, Tachikawa M, Hosoya KI.
    Fluids Barriers CNS; 2022 Jun 03; 19(1):42. PubMed ID: 35658878
    [Abstract] [Full Text] [Related]

  • 15. Contribution of monocarboxylate transporter 12 to blood supply of creatine on the sinusoidal membrane of the hepatocytes.
    Jomura R, Tanno Y, Akanuma SI, Kubo Y, Tachikawa M, Hosoya KI.
    Am J Physiol Gastrointest Liver Physiol; 2021 Aug 01; 321(2):G113-G122. PubMed ID: 34075817
    [Abstract] [Full Text] [Related]

  • 16. GAT2/BGT-1 as a system responsible for the transport of gamma-aminobutyric acid at the mouse blood-brain barrier.
    Takanaga H, Ohtsuki S, Hosoya Ki, Terasaki T.
    J Cereb Blood Flow Metab; 2001 Oct 01; 21(10):1232-9. PubMed ID: 11598501
    [Abstract] [Full Text] [Related]

  • 17. Evidence that the inhibitory effects of guanidinoacetate on the activities of the respiratory chain, Na+,K+-ATPase and creatine kinase can be differentially prevented by taurine and vitamins E and C administration in rat striatum in vivo.
    Zugno AI, Scherer EB, Mattos C, Ribeiro CA, Wannmacher CM, Wajner M, Wyse AT.
    Biochim Biophys Acta; 2007 May 01; 1772(5):563-9. PubMed ID: 17407807
    [Abstract] [Full Text] [Related]

  • 18. Solute carrier SLC16A12 is critical for creatine and guanidinoacetate handling in the kidney.
    Verouti SN, Lambert D, Mathis D, Pathare G, Escher G, Vogt B, Fuster DG.
    Am J Physiol Renal Physiol; 2021 Mar 01; 320(3):F351-F358. PubMed ID: 33459166
    [Abstract] [Full Text] [Related]

  • 19. Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism.
    Neu A, Neuhoff H, Trube G, Fehr S, Ullrich K, Roeper J, Isbrandt D.
    Neurobiol Dis; 2002 Nov 01; 11(2):298-307. PubMed ID: 12505422
    [Abstract] [Full Text] [Related]

  • 20. Functional characterization of Zn2(+)-sensitive GABA transporter expressed in primary cultures of astrocytes from rat cerebral cortex.
    Wu Q, Wada M, Shimada A, Yamamoto A, Fujita T.
    Brain Res; 2006 Feb 23; 1075(1):100-9. PubMed ID: 16466645
    [Abstract] [Full Text] [Related]

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