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Journal Abstract Search

180 related items for PubMed ID: 22402139

  • 1. Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis.
    Horn A, Kireva T, Palumbo-Zerr K, Dees C, Tomcik M, Cordazzo C, Zerr P, Akhmetshina A, Ruat M, Distler O, Beyer C, Schett G, Distler JH.
    Ann Rheum Dis; 2012 May; 71(5):785-9. PubMed ID: 22402139
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  • 2. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Liang R, Šumová B, Cordazzo C, Mallano T, Zhang Y, Wohlfahrt T, Dees C, Ramming A, Krasowska D, Michalska-Jakubus M, Distler O, Schett G, Šenolt L, Distler JH.
    Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
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  • 4. Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.
    Tomcik M, Zerr P, Pitkowski J, Palumbo-Zerr K, Avouac J, Distler O, Becvar R, Senolt L, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1215-22. PubMed ID: 23661493
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  • 5. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 May; 74(5):936-43. PubMed ID: 24431397
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  • 7. Vitamin D receptor regulates TGF-β signalling in systemic sclerosis.
    Zerr P, Vollath S, Palumbo-Zerr K, Tomcik M, Huang J, Distler A, Beyer C, Dees C, Gela K, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 Mar; 74(3):e20. PubMed ID: 24448349
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  • 12. Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.
    Huang J, Beyer C, Palumbo-Zerr K, Zhang Y, Ramming A, Distler A, Gelse K, Distler O, Schett G, Wollin L, Distler JH.
    Ann Rheum Dis; 2016 May; 75(5):883-90. PubMed ID: 25858641
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  • 13. Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
    Chen CW, Beyer C, Liu J, Maier C, Li C, Trinh-Minh T, Xu X, Cole SH, Hsieh MH, Ng N, Althage A, Meeusen S, Pan S, Svensson EC, Seidel HM, Schett G, Gergely P, Harris JL, Distler JH.
    Ann Rheum Dis; 2017 Apr; 76(4):773-778. PubMed ID: 28153829
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  • 15. Inhibition of the hedgehog pathway leads to antifibrotic effects in dermal fibrosis.
    Cao HL, Zhou J, Chen XB, Landeck L, Yang JQ, Chen JQ, Li W, Cai SQ, Zheng M, Man XY.
    Discov Med; 2016 Nov; 22(122):311-318. PubMed ID: 28009972
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  • 17. Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.
    Distler A, Lang V, Del Vecchio T, Huang J, Zhang Y, Beyer C, Lin NY, Palumbo-Zerr K, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1264-8. PubMed ID: 24445254
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  • 18. JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.
    Dees C, Tomcik M, Palumbo-Zerr K, Distler A, Beyer C, Lang V, Horn A, Zerr P, Zwerina J, Gelse K, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2012 Sep; 64(9):3006-15. PubMed ID: 22549363
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  • 19. Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.
    Horn A, Palumbo K, Cordazzo C, Dees C, Akhmetshina A, Tomcik M, Zerr P, Avouac J, Gusinde J, Zwerina J, Roudaut H, Traiffort E, Ruat M, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2012 Aug; 64(8):2724-33. PubMed ID: 22354771
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  • 20. Activation of pregnane X receptor inhibits experimental dermal fibrosis.
    Beyer C, Skapenko A, Distler A, Dees C, Reichert H, Munoz L, Leipe J, Schulze-Koops H, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2013 Apr; 72(4):621-5. PubMed ID: 23291432
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