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Journal Abstract Search

250 related items for PubMed ID: 22404396

  • 1. Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity.
    Yamakawa N, Suemasu S, Okamoto Y, Tanaka K, Ishihara T, Asano T, Miyata K, Otsuka M, Mizushima T.
    J Med Chem; 2012 Jun 14; 55(11):5143-50. PubMed ID: 22404396
    [Abstract] [Full Text] [Related]

  • 2. Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities.
    Yamakawa N, Suemasu S, Matoyama M, Kimoto A, Takeda M, Tanaka K, Ishihara T, Katsu T, Okamoto Y, Otsuka M, Mizushima T.
    J Med Chem; 2010 Nov 11; 53(21):7879-82. PubMed ID: 20954731
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of loxoprofen derivatives.
    Yamakawa N, Suemasu S, Matoyama M, Tanaka K, Katsu T, Miyata K, Okamoto Y, Otsuka M, Mizushima T.
    Bioorg Med Chem; 2011 Jun 01; 19(11):3299-311. PubMed ID: 21570308
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1-phenylpyrazolo[3,4-d]pyrimidine derivatives.
    Bakr RB, Azouz AA, Abdellatif KR.
    J Enzyme Inhib Med Chem; 2016 Jun 01; 31(sup2):6-12. PubMed ID: 27210522
    [Abstract] [Full Text] [Related]

  • 5. Analogue-based design, synthesis and molecular docking analysis of 2,3-diaryl quinazolinones as non-ulcerogenic anti-inflammatory agents.
    Manivannan E, Chaturvedi SC.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4520-8. PubMed ID: 21724403
    [Abstract] [Full Text] [Related]

  • 6. 1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity.
    Abdel-Aziz M, Beshr EA, Abdel-Rahman IM, Ozadali K, Tan OU, Aly OM.
    Eur J Med Chem; 2014 Apr 22; 77():155-65. PubMed ID: 24631895
    [Abstract] [Full Text] [Related]

  • 7. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez C, Praveen Rao PN, Knaus EE.
    J Med Chem; 2005 Jun 16; 48(12):4061-7. PubMed ID: 15943479
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
    Banerjee AG, Das N, Shengule SA, Srivastava RS, Shrivastava SK.
    Eur J Med Chem; 2015 Aug 28; 101():81-95. PubMed ID: 26117820
    [Abstract] [Full Text] [Related]

  • 9. Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.
    Huang Z, Velázquez CA, Abdellatif KR, Chowdhury MA, Reisz JA, DuMond JF, King SB, Knaus EE.
    J Med Chem; 2011 Mar 10; 54(5):1356-64. PubMed ID: 21280601
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
    Song Y, Connor DT, Doubleday R, Sorenson RJ, Sercel AD, Unangst PC, Roth BD, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD.
    J Med Chem; 1999 Apr 08; 42(7):1151-60. PubMed ID: 10197959
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of new pyrazolone-pyridazine conjugates as anti-inflammatory and analgesic agents.
    Khalil NA, Ahmed EM, Mohamed KO, Nissan YM, Zaitone SA.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2080-9. PubMed ID: 24631365
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidines as anti-inflammatory agents.
    Tageldin GN, Fahmy SM, Ashour HM, Khalil MA, Nassra RA, Labouta IM.
    Bioorg Chem; 2018 Aug 01; 78():358-371. PubMed ID: 29627656
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents.
    Palkar MB, Singhai AS, Ronad PM, Vishwanathswamy AH, Boreddy TS, Veerapur VP, Shaikh MS, Rane RA, Karpoormath R.
    Bioorg Med Chem; 2014 May 15; 22(10):2855-66. PubMed ID: 24751552
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and anti-inflammatory assessment of certain substituted 1,2,4-triazoles bearing tetrahydroisoquinoline scaffold as COX 1/2-inhibitors.
    Abo-Elmagd MI, Hassan RM, Aboutabl ME, Amin KM, El-Azzouny AA, Aboul-Enein MN.
    Bioorg Chem; 2024 Sep 15; 150():107577. PubMed ID: 38941697
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and crystallographic analysis of benzophenone derivatives--the potential anti-inflammatory agents.
    Venu TD, Shashikanth S, Khanum SA, Naveen S, Firdouse A, Sridhar MA, Shashidhara Prasad J.
    Bioorg Med Chem; 2007 May 15; 15(10):3505-14. PubMed ID: 17376692
    [Abstract] [Full Text] [Related]

  • 16. Amide derivatives of [5-chloro-6-(2-chloro/fluorobenzoyl)-2-benzoxazolinone-3-yl]acetic acids as potential analgesic and anti-inflammatory compounds.
    Banoglu E, Okçelik B, Kupeli E, Unlü S, Yeşilada E, Amat M, Caturla JF, Sahin MF.
    Arch Pharm (Weinheim); 2003 Jul 15; 336(4-5):251-7. PubMed ID: 12916060
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK, Singh VP, Yadav P, Gupta G, Singh A, Goel RK, Shinde P, Mohan CG.
    Bioorg Chem; 2014 Oct 15; 56():8-15. PubMed ID: 24893208
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
    Song Y, Connor DT, Sercel AD, Sorenson RJ, Doubleday R, Unangst PC, Roth BD, Beylin VG, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD.
    J Med Chem; 1999 Apr 08; 42(7):1161-9. PubMed ID: 10197960
    [Abstract] [Full Text] [Related]

  • 19. [Synthesis and anti-inflammatory activity of alpha-substituted p-(methanesulfonyl)phenylpropenamides].
    Ao GZ, Zhang YH, Ji H, Deng G.
    Yao Xue Xue Bao; 2003 Sep 08; 38(9):671-6. PubMed ID: 14730916
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, Anti-Inflammatory Activity, and COX-1/2 Inhibition Profile of Some Novel Non-Acidic Polysubstituted Pyrazoles and Pyrano[2,3-c]pyrazoles.
    Faidallah HM, Rostom SAF.
    Arch Pharm (Weinheim); 2017 May 08; 350(5):. PubMed ID: 28370254
    [Abstract] [Full Text] [Related]

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