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769 related items for PubMed ID: 22415077

  • 1. Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.
    Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M.
    Cell Physiol Biochem; 2012; 29(1-2):75-86. PubMed ID: 22415077
    [Abstract] [Full Text] [Related]

  • 2. Activation of the AMP-activated protein kinase enhances glucose-stimulated insulin secretion in mouse β-cells.
    Düfer M, Noack K, Krippeit-Drews P, Drews G.
    Islets; 2010; 2(3):156-63. PubMed ID: 21099309
    [Abstract] [Full Text] [Related]

  • 3. AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic β-cell Apoptosis via Differential Downstream Mechanisms.
    Dai YL, Huang SL, Leng Y.
    Int J Biol Sci; 2015; 11(11):1272-80. PubMed ID: 26435693
    [Abstract] [Full Text] [Related]

  • 4. Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the K(ATP) channel and insulin secretion in rats.
    Chang TJ, Chen WP, Yang C, Lu PH, Liang YC, Su MJ, Lee SC, Chuang LM.
    Diabetologia; 2009 Jun; 52(6):1112-21. PubMed ID: 19357830
    [Abstract] [Full Text] [Related]

  • 5. The H+/K+ ATPase Inhibitor SCH-28080 Inhibits Insulin Secretion and Induces Cell Death in INS-1E Rat Insulinoma Cells.
    Jakab M, Ketterl N, Fürst J, Beyreis M, Kittl M, Kiesslich T, Hauser-Kronberger C, Gaisberger M, Ritter M.
    Cell Physiol Biochem; 2017 Jun; 43(3):1037-1051. PubMed ID: 28968600
    [Abstract] [Full Text] [Related]

  • 6. Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells.
    Guo H, Zhang XJ, Wang F, Wang Y, Shen Y, Zhao JJ, Gao L.
    J Endocrinol Invest; 2010 Jun; 33(7):465-71. PubMed ID: 20101096
    [Abstract] [Full Text] [Related]

  • 7. Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells.
    ElAzzouny MA, Evans CR, Burant CF, Kennedy RT.
    PLoS One; 2015 Jun; 10(6):e0129029. PubMed ID: 26107620
    [Abstract] [Full Text] [Related]

  • 8. AMP-activated protein kinase agonist dose dependently improves function and reduces apoptosis in glucotoxic beta-cells without changing triglyceride levels.
    Nyblom HK, Sargsyan E, Bergsten P.
    J Mol Endocrinol; 2008 Sep; 41(3):187-94. PubMed ID: 18579684
    [Abstract] [Full Text] [Related]

  • 9. 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-induced AMP-activated protein kinase phosphorylation inhibits basal and insulin-stimulated glucose uptake, lipid synthesis, and fatty acid oxidation in isolated rat adipocytes.
    Gaidhu MP, Fediuc S, Ceddia RB.
    J Biol Chem; 2006 Sep 08; 281(36):25956-64. PubMed ID: 16816404
    [Abstract] [Full Text] [Related]

  • 10. Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation.
    Anthony NM, Gaidhu MP, Ceddia RB.
    Obesity (Silver Spring); 2009 Jul 08; 17(7):1312-7. PubMed ID: 19214174
    [Abstract] [Full Text] [Related]

  • 11. 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.
    Ségalen C, Longnus SL, Baetz D, Counillon L, Van Obberghen E.
    Endocrinology; 2008 Apr 08; 149(4):1490-8. PubMed ID: 18187546
    [Abstract] [Full Text] [Related]

  • 12. AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D.
    Zang Y, Yu LF, Nan FJ, Feng LY, Li J.
    J Biol Chem; 2009 Mar 06; 284(10):6175-84. PubMed ID: 19144636
    [Abstract] [Full Text] [Related]

  • 13. 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
    Wang CZ, Wang Y, Di A, Magnuson MA, Ye H, Roe MW, Nelson DJ, Bell GI, Philipson LH.
    Biochem Biophys Res Commun; 2005 May 20; 330(4):1073-9. PubMed ID: 15823553
    [Abstract] [Full Text] [Related]

  • 14. Regulation of glucose-dependent insulin secretion by insulin: possible role of AMP-activated protein kinase.
    Park SH, Kim SY, Baek WK, Lim B, Park JH, Sung HY, Kim YK, Bae KC, Bae JH, Song DK.
    Life Sci; 2009 Jul 17; 85(3-4):178-83. PubMed ID: 19481554
    [Abstract] [Full Text] [Related]

  • 15. Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity.
    Mountjoy PD, Bailey SJ, Rutter GA.
    Diabetologia; 2007 Jan 17; 50(1):168-77. PubMed ID: 17093945
    [Abstract] [Full Text] [Related]

  • 16. Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms.
    Yang W, Yang G, Jia X, Wu L, Wang R.
    J Physiol; 2005 Dec 01; 569(Pt 2):519-31. PubMed ID: 16179362
    [Abstract] [Full Text] [Related]

  • 17. AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C.
    Vucicevic L, Misirkic M, Janjetovic K, Harhaji-Trajkovic L, Prica M, Stevanovic D, Isenovic E, Sudar E, Sumarac-Dumanovic M, Micic D, Trajkovic V.
    Biochem Pharmacol; 2009 Jun 01; 77(11):1684-93. PubMed ID: 19428322
    [Abstract] [Full Text] [Related]

  • 18. Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells.
    Woollhead AM, Sivagnanasundaram J, Kalsi KK, Pucovsky V, Pellatt LJ, Scott JW, Mustard KJ, Hardie DG, Baines DL.
    Br J Pharmacol; 2007 Aug 01; 151(8):1204-15. PubMed ID: 17603555
    [Abstract] [Full Text] [Related]

  • 19. 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.
    Salt IP, Connell JM, Gould GW.
    Diabetes; 2000 Oct 01; 49(10):1649-56. PubMed ID: 11016448
    [Abstract] [Full Text] [Related]

  • 20. Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells.
    Turban S, Stretton C, Drouin O, Green CJ, Watson ML, Gray A, Ross F, Lantier L, Viollet B, Hardie DG, Marette A, Hundal HS.
    J Biol Chem; 2012 Jun 08; 287(24):20088-99. PubMed ID: 22511782
    [Abstract] [Full Text] [Related]

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