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Journal Abstract Search

167 related items for PubMed ID: 2242301

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  • 2. Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
    Dolan ME, Moschel RC, Pegg AE.
    Proc Natl Acad Sci U S A; 1990 Jul; 87(14):5368-72. PubMed ID: 2164681
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  • 4. Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.
    Dolan ME, Pegg AE, Dumenco LL, Moschel RC, Gerson SL.
    Carcinogenesis; 1991 Dec; 12(12):2305-9. PubMed ID: 1747932
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  • 5. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
    Dolan ME, Mitchell RB, Mummert C, Moschel RC, Pegg AE.
    Cancer Res; 1991 Jul 01; 51(13):3367-72. PubMed ID: 1647266
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  • 8. Effect of O6-benzylguanine on the response to 1,3-bis(2-chloroethyl)-1-nitrosourea in the Dunning R3327G model of prostatic cancer.
    Dolan ME, Pegg AE, Biser ND, Moschel RC, English HF.
    Cancer Chemother Pharmacol; 1993 Jul 01; 32(3):221-5. PubMed ID: 8500228
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  • 9. Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.
    Friedman HS, Dolan ME, Moschel RC, Pegg AE, Felker GM, Rich J, Bigner DD, Schold SC.
    J Natl Cancer Inst; 1992 Dec 16; 84(24):1926-31. PubMed ID: 1334154
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  • 10. Metabolism of O6-benzylguanine, an inactivator of O6-alkylguanine-DNA alkyltransferase.
    Dolan ME, Chae MY, Pegg AE, Mullen JH, Friedman HS, Moschel RC.
    Cancer Res; 1994 Oct 01; 54(19):5123-30. PubMed ID: 7923129
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  • 11. Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to 1,3-bis(2-chloroethyl)-1-nitrosourea and on DNA interstrand cross-link formation.
    Mitchell RB, Moschel RC, Dolan ME.
    Cancer Res; 1992 Mar 01; 52(5):1171-5. PubMed ID: 1737376
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  • 13. Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
    Dolan ME, Larkin GL, English HF, Pegg AE.
    Cancer Chemother Pharmacol; 1989 Mar 01; 25(2):103-8. PubMed ID: 2557168
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  • 15. Phase I clinical trial of O6-benzylguanine and topical carmustine in the treatment of cutaneous T-cell lymphoma, mycosis fungoides type.
    Apisarnthanarax N, Wood GS, Stevens SR, Carlson S, Chan DV, Liu L, Szabo SK, Fu P, Gilliam AC, Gerson SL, Remick SC, Cooper KD.
    Arch Dermatol; 2012 May 01; 148(5):613-20. PubMed ID: 22250189
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  • 16. Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N'-bis (2-chloroethyl)-N-nitrosourea.
    Loktionova NA, Pegg AE.
    Cancer Res; 1996 Apr 01; 56(7):1578-83. PubMed ID: 8603405
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  • 17. Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.
    Pegg AE, Boosalis M, Samson L, Moschel RC, Byers TL, Swenn K, Dolan ME.
    Biochemistry; 1993 Nov 16; 32(45):11998-2006. PubMed ID: 8218276
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  • 18. O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
    Brent TP, Houghton PJ, Houghton JA.
    Proc Natl Acad Sci U S A; 1985 May 16; 82(9):2985-9. PubMed ID: 3857628
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  • 19. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
    Chen JM, Zhang YP, Sui JL, Moschel RC, Ikenaga M.
    Anticancer Res; 1993 May 16; 13(3):801-5. PubMed ID: 8317915
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  • 20. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
    Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME.
    J Pharmacol Exp Ther; 2005 Dec 16; 315(3):1247-55. PubMed ID: 16126841
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